Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Jiří, Šponer"'
Autor:
Judit E. Šponer, Rémi Coulon, Michal Otyepka, Jiří Šponer, Alexander F. Siegle, Oliver Trapp, Katarzyna Ślepokura, Zbyněk Zdráhal, Ondrej Šedo
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Because of their unique proton-conductivity, chains of phosphoric acid molecules are excellent proton-transfer catalysts. Here we demonstrate that this property could have been exploited for the prebiotic synthesis of the first oligopeptide
Externí odkaz:
https://doaj.org/article/f6c7926ac9304936817c365f3fcf9b70
Autor:
Judit E. Šponer, Jiří Šponer, Jakub Výravský, Roman Matyášek, Aleš Kovařík, Wojciech Dudziak, Katarzyna Ślepokura
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107600- (2023)
Summary: Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet. In the current work we propose that guanosine 3′,5′ cyclic monophosphate could selectively
Externí odkaz:
https://doaj.org/article/d354cccee2204ddd89f10ef7be4b0a46
Autor:
Chad R. Simmons, Tara MacCulloch, Miroslav Krepl, Michael Matthies, Alex Buchberger, Ilyssa Crawford, Jiří Šponer, Petr Šulc, Nicholas Stephanopoulos, Hao Yan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Engineered crystal architectures from DNA have become a foundational goal for nanotechnological precise arrangement. Here, the authors systematically investigate the structures of 36 immobile Holliday junction sequences and identify the features allo
Externí odkaz:
https://doaj.org/article/cd7ac15173d44a0ea3bc7db8f340602d
Autor:
Rafał Szabla, Magdalena Zdrowowicz, Paulina Spisz, Nicholas J. Green, Petr Stadlbauer, Holger Kruse, Jiří Šponer, Janusz Rak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
UV-induced photodamage that likely occurred during the prebiotic synthesis of DNA and RNA is still an untackled issue for their origin on early Earth. Here, the authors show that substitution of 2,6-diaminopurine for adenine enables repair of cyclobu
Externí odkaz:
https://doaj.org/article/347696f7b33c4b0fa6bc7bc725ea0853
Autor:
Martin Ferus, Giuseppe Cassone, Vladimír Táborský, Alan Heays, Lukáš Petera, Antonín Knížek, Tadeáš Kalvoda, Milan Bouša, Jiří Šponer, Judit E. Šponer, Petr Kubelík, Jan Drápal, Jan Stehlík, Svatopluk Civiš
Publikováno v:
ACS Omega, Vol 6, Iss 22, Pp 14447-14457 (2021)
Externí odkaz:
https://doaj.org/article/077a1bff84a7493cbf4f28c601659d43
Autor:
Martin Ferus, Antonín Knížek, Lukáš Petera, Adam Pastorek, Jana Hrnčířová, Luboš Jankovič, Ondřej Ivanek, Jiří Šponer, Anna Křivková, Homa Saeidfirozeh, Svatopluk Civiš, Elias Chatzitheodoridis, Klaudia Mráziková, Lukáš Nejdl, Franz Saija, Judit E. Šponer, Giuseppe Cassone
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 9 (2022)
Influx of matter from impacting meteoroids and hydrothermal crater weathering are important factors modifying the rock and mineral inventory of young planets undergoing heavy bombardment. These processes may have influenced not only the geochemical e
Externí odkaz:
https://doaj.org/article/79660086ea8d49d19f4da59653d367b1
Autor:
Krishna C. Suddala, Ian R. Price, Shiba S. Dandpat, Michal Janeček, Petra Kührová, Jiří Šponer, Pavel Banáš, Ailong Ke, Nils G. Walter
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion
Externí odkaz:
https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
Autor:
Karolina Maria Górecka, Miroslav Krepl, Aleksandra Szlachcic, Jarosław Poznański, Jiří Šponer, Marcin Nowotny
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completio
Externí odkaz:
https://doaj.org/article/ee4f387405724f7facf85dd79c1e37a1
Publikováno v:
Journal of Chemical Information and Modeling. 63:2133-2146
Publikováno v:
The Journal of Physical Chemistry B. 126:9207-9221
RNA-protein complexes use diverse binding strategies, ranging from structurally well-defined interfaces to completely disordered regions. Experimental characterization of flexible segments is challenging and can be aided by atomistic molecular dynami