Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jhon Alexander Marin Soto"'
Autor:
Ravi S. Narayan, Piet Molenaar, Jian Teng, Fleur M. G. Cornelissen, Irene Roelofs, Renee Menezes, Rogier Dik, Tonny Lagerweij, Yoran Broersma, Naomi Petersen, Jhon Alexander Marin Soto, Eelke Brands, Philip van Kuiken, Maria C. Lecca, Kristiaan J. Lenos, Sjors G. J. G. In ‘t Veld, Wessel van Wieringen, Frederick F. Lang, Erik Sulman, Roel Verhaak, Brigitta G. Baumert, Lucas J. A. Stalpers, Louis Vermeulen, Colin Watts, David Bailey, Ben J. Slotman, Rogier Versteeg, David Noske, Peter Sminia, Bakhos A. Tannous, Tom Wurdinger, Jan Koster, Bart A. Westerman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Drug synergies impact the efficacy of combination therapies but are difficult to identify. Here Narayan et al. describe the drug atlas, a method to predict effective drug combinations from common exclusive drug effects providing a resource for explor
Externí odkaz:
https://doaj.org/article/379bf84492484b43b2eac920159ae273
Autor:
Brigitta G. Baumert, Erik P. Sulman, Jan Koster, Rogier Dik, Yoran Broersma, Tonny Lagerweij, Rogier Versteeg, Lucas J A Stalpers, D. P. Noske, Irene Roelofs, Jhon Alexander Marin Soto, Sjors G J G In 't Veld, Peter Sminia, Naomi Petersen, Louis Vermeulen, Maria C. Lecca, Eelke Brands, Ravi S. Narayan, Bakhos A. Tannous, Renée X. de Menezes, David Bailey, Jian Teng, Bart A Westerman, Ben J. Slotman, Thomas Wurdinger, Piet Molenaar, Fleur M G Cornelissen, Roel G.W. Verhaak, Colin Watts, Frederick F. Lang, Kristiaan J. Lenos, Wessel N. van Wieringen, Philip van Kuiken
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2935. Nature Publishing Group
Nature Communications, 11(1):2935
Narayan, R S, Molenaar, P, Teng, J, Cornelissen, F M G, Roelofs, I, Menezes, R, Dik, R, Lagerweij, T, Broersma, Y, Petersen, N, Marin Soto, J A, Brands, E, van Kuiken, P, Lecca, M C, Lenos, K J, Int Veld, S G J G, van Wieringen, W, Lang, F F, Sulman, E, Verhaak, R, Baumert, B G, Stalpers, L J A, Vermeulen, L, Watts, C, Bailey, D, Slotman, B J, Versteeg, R, Noske, D, Sminia, P, Tannous, B A, Wurdinger, T, Koster, J & Westerman, B A 2020, ' A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities ', Nature Communications, vol. 11, no. 1, 2935 . https://doi.org/10.1038/s41467-020-16735-2, https://doi.org/10.1038/s41467-020-16735-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2935. Nature Publishing Group
Nature Communications, 11(1):2935
Narayan, R S, Molenaar, P, Teng, J, Cornelissen, F M G, Roelofs, I, Menezes, R, Dik, R, Lagerweij, T, Broersma, Y, Petersen, N, Marin Soto, J A, Brands, E, van Kuiken, P, Lecca, M C, Lenos, K J, Int Veld, S G J G, van Wieringen, W, Lang, F F, Sulman, E, Verhaak, R, Baumert, B G, Stalpers, L J A, Vermeulen, L, Watts, C, Bailey, D, Slotman, B J, Versteeg, R, Noske, D, Sminia, P, Tannous, B A, Wurdinger, T, Koster, J & Westerman, B A 2020, ' A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities ', Nature Communications, vol. 11, no. 1, 2935 . https://doi.org/10.1038/s41467-020-16735-2, https://doi.org/10.1038/s41467-020-16735-2
Personalized cancer treatments using combinations of drugs with a synergistic effect is attractive but proves to be highly challenging. Here we present an approach to uncover the efficacy of drug combinations based on the analysis of mono-drug effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45881133c5d8ff689a4a73ac06a72035
http://europepmc.org/articles/PMC7287046
http://europepmc.org/articles/PMC7287046