Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jhih-Hang Jiang"'
Autor:
Xiangfeng Lai, Mei-Ling Han, Yue Ding, Seong Hoong Chow, Anton P. Le Brun, Chun-Ming Wu, Phillip J. Bergen, Jhih-hang Jiang, Hsien-Yi Hsu, Benjamin W. Muir, Jacinta White, Jiangning Song, Jian Li, Hsin-Hui Shen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
An increasing prevalence of Gram-negative bacteria increases the interest in nanotherapies to treat antibiotic resistance. Here, the authors examine the antimicrobial activity of polymyxin-loaded cubosomes and explore a polytherapy treatment of patho
Externí odkaz:
https://doaj.org/article/d8e96a05c7f74f2abf5c77c18c5a49db
Autor:
Maoge Zang, Hugo MacDermott-Opeskin, Felise G. Adams, Varsha Naidu, Jack K. Waters, Ashley B. Carey, Alex Ashenden, Kimberley T. McLean, Erin B. Brazel, Jhih-Hang Jiang, Alessandra Panizza, Claudia Trappetti, James C. Paton, Anton Y. Peleg, Ingo Köper, Ian T. Paulsen, Karl A. Hassan, Megan L. O’Mara, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Antimicrobial resistance is an emerging global health crisis. Consequently, we have a critical need to prolong our current arsenal of antibiotics, in addition to the development of novel treatment options.
Externí odkaz:
https://doaj.org/article/6d0881cf57d441f7bee271a358bfc5d7
Autor:
Joshua D. Ooi, Jhih-Hang Jiang, Peter J. Eggenhuizen, Ling L. Chua, Mirjan van Timmeren, Khai L. Loh, Kim M. O’Sullivan, Poh Y. Gan, Yong Zhong, Kirill Tsyganov, Lani R. Shochet, Jessica Ryan, Coen A. Stegeman, Lars Fugger, Hugh H. Reid, Jamie Rossjohn, Peter Heeringa, Stephen R. Holdsworth, Anton Y. Peleg, A. Richard Kitching
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Autoreactivity to myeloperoxidase (MPO) causes autoimmune vasculitis and severe glomerulonephritis. Here, Ooi et al. show that a Staphylococcus aureus plasmid encodes a peptide that is homologous to an immunodominant MPO epitope and induces anti-MPO
Externí odkaz:
https://doaj.org/article/ec5422e66a47466790d6d136a48ebe74
Autor:
Jhih-Hang Jiang, Karl A. Hassan, Stephanie L. Begg, Thusitha W. T. Rupasinghe, Varsha Naidu, Victoria G. Pederick, Marjan Khorvash, Jonathan J. Whittall, James C. Paton, Ian T. Paulsen, Christopher A. McDevitt, Anton Y. Peleg, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Free fatty acids hold important immune-modulatory roles during infection. However, the host’s long-chain polyunsaturated fatty acids, not commonly found in the membranes of bacterial pathogens, also have significant broad-spectrum antibact
Externí odkaz:
https://doaj.org/article/9d970be129be462eb8daae5917e68e67
Autor:
Md Saruar Bhuiyan, Jhih-Hang Jiang, Xenia Kostoulias, Ravali Theegala, Graham J. Lieschke, Anton Y. Peleg
Publikováno v:
Antibiotics, Vol 10, Iss 2, p 96 (2021)
Daptomycin is an important antibiotic for the treatment of infections caused by Staphylococcus aureus. The emergence of daptomycin resistance in S. aureus is associated with treatment failure and persistent infections with poor clinical outcomes. Her
Externí odkaz:
https://doaj.org/article/7f0cbfa4d73843aea0fffb1beb9e8475
Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.
Autor:
Pankaj Deo, Seong H Chow, Iain D Hay, Oded Kleifeld, Adam Costin, Kirstin D Elgass, Jhih-Hang Jiang, Georg Ramm, Kipros Gabriel, Gordon Dougan, Trevor Lithgow, Eva Heinz, Thomas Naderer
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006945 (2018)
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake.
Externí odkaz:
https://doaj.org/article/19a370dd541c457a8aeece8ff5d25289
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 7, Pp 8038-8050 (2012)
β-barrel proteins are the highly abundant in the outer membranes of Gram-negative bacteria and the mitochondria in eukaryotes. The assembly of β-barrels is mediated by two evolutionary conserved machineries; the β-barrel Assembly Machinery (BAM) i
Externí odkaz:
https://doaj.org/article/1a6a364cf93c46abbd5e2c27a600132b
Autor:
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002459 (2012)
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to
Externí odkaz:
https://doaj.org/article/0f5d265e5d654a888748be2592c79cc4
Autor:
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M. T. Marobbio, Sau fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L. Hartland, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/e0f508f5424540a6bdf51e8a6cccb35c
Autor:
Jhih-Hang Jiang, 江志航
95
Na+/Ca2+ exchanger (NCX) catalyzes the countertransport of three Na+ for one Ca2+ and is present in the plasma membrane of most cells, especially in cardiac muscle and brain which require extracellular Ca2+ for their physiological activities.
Na+/Ca2+ exchanger (NCX) catalyzes the countertransport of three Na+ for one Ca2+ and is present in the plasma membrane of most cells, especially in cardiac muscle and brain which require extracellular Ca2+ for their physiological activities.
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/33932012429367220361