Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jhih Rong Lin"'
Autor:
Bhaskar Jyoti Borah, Yao-Chen Tseng, Kuo-Chuan Wang, Huan-Chih Wang, Hsin-Yi Huang, Koping Chang, Jhih Rong Lin, Yi-Hua Liao, Chi-Kuang Sun
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-16 (2023)
Abstract Background Hematoxylin and Eosin (H&E)-based frozen section (FS) pathology is presently the global standard for intraoperative tumor assessment (ITA). Preparation of frozen section is labor intensive, which might consume up-to 30 minutes, an
Externí odkaz:
https://doaj.org/article/10da6747e69b4f36915e74965ea95116
Autor:
Zhen Wang, Quanwei Zhang, Jhih-Rong Lin, M. Reza Jabalameli, Joydeep Mitra, Nha Nguyen, Zhengdong D. Zhang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is a genetically complex, multifactorial neurodegenerative disease. It affects more than 45 million people worldwide and currently remains untreatable. Although genome-wide association studies (GWAS) have identifie
Externí odkaz:
https://doaj.org/article/d240b06944584aa79ba071b19c689ac5
Autor:
Koping Chang, Wei-Kang Yang, Wan-Ting Li, Ti-Yen Yeh, Chia-Hsuan Jao, Jhih Rong Lin, Cheng Chen Lin, Yung-Ming Jeng, Chi-Chao Chao, Sung-Tsang Hsieh
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 81:363-376
Hereditary transthyretin (ATTRv) amyloidosis is a systemic disease with amyloid deposition in the peripheral and autonomic nervous systems caused by mutation of transthyretin (TTR) gene. The mutant TTR S77Y is the second prevalent mutation in many co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828aa36f5502274213e004034454e669
https://doi.org/10.1093/jnen/nlac022
https://doi.org/10.1093/jnen/nlac022
Autor:
Cheng-Chen, Chang, Po See, Chen, Jhih-Rong, Lin, Yi-An, Chen, Chin-San, Liu, Ta-Tsung, Lin, Hui Hua, Chang
Publikováno v:
International Journal of Neuropsychopharmacology. 25:525-533
Background Bipolar disorder (BD) is associated with cognitive impairment and mitochondrial dysfunction. However, the associations among mitochondrial DNA copy number (MCN), treatment response, and cognitive function remain elusive in BD patients. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1454eea60dcaa659d28249960c0d0b9
https://doi.org/10.1093/ijnp/pyab095
https://doi.org/10.1093/ijnp/pyab095
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007142 (2017)
Rare variants of major effect play an important role in human complex diseases and can be discovered by sequencing-based genome-wide association studies. Here, we introduce an integrated approach that combines the rare variant association test with g
Externí odkaz:
https://doaj.org/article/2a97883dc59a454f8e44fe214afb992e
Autor:
Vera Gorbunova, Joydeep Mitra, Tina Gao, M. Reza Jabalameli, Almut Nebel, Matthias Laudes, Paul D. Robbins, Siegfried Görg, Quanwei Zhang, Alan R. Shuldiner, Valerio Napolioni, Kenny Ye, Nir Barzilai, Gil Atzmon, Warren C. Ladiges, Sofiya Milman, Yousin Suh, Guillermo G. Torres, Nha Nguyen, Zhengdong Zhang, Michael D. Greicius, Zhen Wang, Jhih Rong Lin, Jan Vijg, Patrick Sin-Chan, Andre Franke, Laura J. Niedernhofer
Publikováno v:
Nature Aging. 1:783-794
Extreme longevity in humans has a strong genetic component, but whether this involves genetic variation in the same longevity pathways as found in model organisms is unclear. Using whole-exome sequences of a large cohort of Ashkenazi Jewish centenari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88639d6837851dd07cacaf6f9b0cb4be
https://doi.org/10.1038/s43587-021-00108-5
https://doi.org/10.1038/s43587-021-00108-5
Autor:
Jhih Rong Lin, Zhen Wang, Quanwei Zhang, M. Reza Jabalameli, Joydeep Mitra, Nha Nguyen, Zhengdong D. Zhang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Alzheimer’s disease (AD) is a genetically complex, multifactorial neurodegenerative disease. It affects more than 45 million people worldwide and currently remains untreatable. Although genome-wide association studies (GWAS) have identified many AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026c928515aa4f29df3493dcb1770ce0
https://doi.org/10.1038/s41598-021-99352-3
https://doi.org/10.1038/s41598-021-99352-3
Autor:
Jhih-rong Lin, Jianjun Hu
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76864 (2013)
Nuclear localization signals (NLSs) are stretches of residues in proteins mediating their importing into the nucleus. NLSs are known to have diverse patterns, of which only a limited number are covered by currently known NLS motifs. Here we propose a
Externí odkaz:
https://doaj.org/article/63683769ffc442f59846f45000b5e4b0
Autor:
Andrei Seluanov, Nha Nguyen, Zhengdong D. Zhang, Vera Gorbunova, Jhih Rong Lin, Lei Zhang, Quanwei Zhang, Zachary J. Smith, Joydeep Mitra, Jan Vijg, Gregory Tombline, Vadim N. Gladyshev, Julia Ablaeva, Xuming Zhou, M. Reza Jabalameli, Alus M. Xiaoli, Zhen Wang
The North American beaver (Castor canadensis) is an exceptionally long-lived and cancer-resistant rodent species, and thus an excellent model organism for comparative genomic studies of longevity. Here, we utilize a significantly improved beaver geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27af2fc397cb28480c45fc8cfae4b39
https://doi.org/10.1101/2020.06.25.171322
https://doi.org/10.1101/2020.06.25.171322
Autor:
ZHEN WANG, Quanwei Zhang, Jhih-Rong Lin, M.Reza Jabalamel, Joydeep Mitra, Nha Nguyen, Zhengdong Zhang
Background: Alzheimer’s disease (AD) is a genetically complex, multifactorial neurodegenerative disease. It affects more than 45 million people worldwide and currently remains untreatable. Although genome-wide association studies (GWAS) have identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ea30f52a313c855f8f0c8025f4c12f
https://doi.org/10.21203/rs.3.rs-31864/v1
https://doi.org/10.21203/rs.3.rs-31864/v1