Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jhe-Hao Li"'
Publikováno v:
J Nat Prod
The entomopathogenic bacterium Xenorhabdus bovienii exists in a mutualistic relationship with nematodes of the genus Steinernema. Free-living infective juveniles (IJs) of Steinernema prey on insect larvae and regurgitate X. bovienii within the hemoco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730a3c81d6ea9cf7acdc066446496be6
https://doi.org/10.1021/acs.jnatprod.1c00573
https://doi.org/10.1021/acs.jnatprod.1c00573
Autor:
Jason M. Crawford, Nam Y. Kim, David Clarke, Ellen L. Zechner, Joonseok Oh, Sabine Kienesberger, Jhe-Hao Li
Publikováno v:
Angewandte Chemie. 132:18028-18036
Leupeptin is a bacterial small molecule that is used worldwide as a protease inhibitor. However, its biosynthesis and genetic distribution remain unknown. We identified a family of leupeptins in gammaproteobacterial pathogens, including Photorhabdus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d1a9042a29eedbacf550fed843995c
https://doi.org/10.1002/ange.202005506
https://doi.org/10.1002/ange.202005506
Autor:
Richard P. Cheng, Ting-Hsuan Chen, Chin-Yi Chen, Jin-Kai Lin, Jhe-Hao Li, Shing-Jong Huang, Po-Yi Wu, Shou-Ling Huang
Publikováno v:
ChemBioChem. 20:2118-2124
Post-translational modifications expand the chemical functionality of peptides and proteins beyond that originating from the encoded amino acids, but studies on the structural effects of these modifications have been limited. Arginine undergoes deimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95ff63e03026aec541557ae754de9db
https://doi.org/10.1002/cbic.201900231
https://doi.org/10.1002/cbic.201900231
Autor:
Thomas P. Wyche, Ashiti Damania, Jhe-Hao Li, Hyun Bong Park, Jason M. Crawford, Nicole K. Clay, Alexandra Gatsios, Grazia Piizzi, Brenden Barco, Rurun Wang, Chung Sub Kim
Publikováno v:
Cell Chemical Biology. 27:698-707.e7
Summary Escherichia coli broadly colonize the intestinal tract of humans and produce a variety of small molecule signals. However, many of these small molecules remain unknown. Here, we describe a family of widely distributed bacterial metabolites te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::269f7d03e5836bfaabb9bd98420fda0d
https://doi.org/10.1016/j.chembiol.2020.03.003
https://doi.org/10.1016/j.chembiol.2020.03.003
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:2281-2286
Arginine (Arg) methylation is a common post-translational modification that regulates gene expression and viral infection. The HIV-1 Tat protein is an essential regulatory protein for HIV proliferation, and is methylated in the cell. The basic region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974e957a1e720bd09d5c84a93a07ae78
https://doi.org/10.1016/j.bmc.2015.01.051
https://doi.org/10.1016/j.bmc.2015.01.051
Autor:
Li-Hung Kuo, Hsin-Yun Tsai, Hsiou-Ting Kuo, Shou-Ling Huang, Tong Wai Wong, Shing-Jong Huang, Cheng Hsun Wu, Cheng-Yun Hung, Wen-Chieh Chiu, Po-An Yang, Jhe-Hao Li, Richard P. Cheng, Wei-Ren Wang, Yun Chiao Yao
Publikováno v:
Biochemistry. 52:7785-7797
β-Sheets have been implicated in various neurological disorders, and ∼20% of protein residues adopt a sheet conformation. Therefore, studies on the structural origin of sheet stability can provide fundamental knowledge with potential biomedical ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532cf692b115dfecd7f596bb9309b9d1
https://doi.org/10.1021/bi400911p
https://doi.org/10.1021/bi400911p
Autor:
Richard P. Cheng, Shou-Ling Huang, Hsiou-Ting Kuo, Wei-Ren Wang, Shing-Lung Liu, Po-An Yang, Hsien-Chen Chang, Jhe-Hao Li, Shing-Jong Huang, Chun-Jen Fang, Wen-Chieh Chiu
Publikováno v:
Amino acids. 47(5)
β-Sheet is one of the major protein secondary structures. Oppositely charged residues are frequently observed across neighboring strands in antiparallel sheets, suggesting the importance of cross-strand ion pairing interactions. The charged amino ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdceb6c138e946f7a65a42e095dfef3
https://pubmed.ncbi.nlm.nih.gov/25646959
https://pubmed.ncbi.nlm.nih.gov/25646959
Publikováno v:
Bioorganicmedicinal chemistry. 22(11)
The six arginine (Arg) residues in the human immunodeficiency virus transactivator of transcription protein (HIV Tat protein) basic region (residues 47–57) are crucial for two bioactivities: RNA recognition and cellular uptake. Herein, we report a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c346508fe4fff15817bf3f3def97b89
https://pubmed.ncbi.nlm.nih.gov/24767816
https://pubmed.ncbi.nlm.nih.gov/24767816
Autor:
Richard P. Cheng, Wei-Ren Wang, Prashant Girinath, Po-An Yang, Raheel Ahmad, Jhe-Hao Li, Pier Hart, Bashkim Kokona, Robert Fairman, Casey Kilpatrick, Annmarie Argiros
Publikováno v:
Biochemistry. 51(36)
Ion pairing interactions between oppositely charged amino acids are important for protein structure stability. Despite the apparent electrostatic nature of these interactions, the charged amino acids Lys, Arg, Glu, and Asp have a different number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b9615bf6ba9ce7378485fb193b2551
https://pubmed.ncbi.nlm.nih.gov/22931137
https://pubmed.ncbi.nlm.nih.gov/22931137
Autor:
Cheng, Richard P., Wei-Ren Wang, Girinath, Prashant, Po-An Yang, Ahmad, Raheel, Jhe-Hao Li, Hart, Pier, Kokona, Bashkim, Fairman, Robert, Kilpatrick, Casey, Argiros, Annmarie
Publikováno v:
Biochemistry; 9/11/2012, Vol. 51 Issue 36, p7157-7172, 16p