Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jharna Mishra"'
Autor:
Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Jharna Mishra, Atul Samaiya, Sanjeev Shukla
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114367- (2024)
Summary: Cancer cells experiencing hypoxic stress employ epithelial-mesenchymal transition (EMT) to undergo metastasis through rewiring of the chromatin landscape, epigenetics, and importantly, gene expression. Here, we showed that hypoxia modulates
Externí odkaz:
https://doaj.org/article/e837af850e4345549f7f1208aee67737
Autor:
Pooja Yadav, Anchala Pandey, Parik Kakani, Srinivas Abhishek Mutnuru, Atul Samaiya, Jharna Mishra, Sanjeev Shukla
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106804- (2023)
Summary: Alternative splicing of vascular endothelial growth factor A (VEGFA) generates numerous isoforms with unique roles in tumor angiogenesis, and investigating the underlying mechanism during hypoxia necessitates diligent pursuance. Our research
Externí odkaz:
https://doaj.org/article/78128716294d4f4cbb5312062688b8fa
Publikováno v:
Oncogenesis, Vol 10, Iss 8, Pp 1-10 (2021)
Abstract Epithelial splicing regulatory protein 1 (ESRP1) is an RNA binding protein that governs the alternative splicing events related to epithelial phenotypes. ESRP1 contributes significantly at different stages of cancer progression. ESRP1 expres
Externí odkaz:
https://doaj.org/article/d1938a6672474734bcbe5fa95f566ca5
Cancer cells experiencing hypoxic stress employ Epithelial-Mesenchymal Transition (EMT) to undergo metastasis through rewiring chromatin landscape, epigenetics, and importantly alternative splicing. Here, we investigated the role of CTCF, chromatin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422f3ed90ce6de92263df90f9fb730b3
https://doi.org/10.1101/2023.05.06.539689
https://doi.org/10.1101/2023.05.06.539689
Autor:
Pooja Yadav, Sanjeev Shukla, Atul Samaiya, Madhura R. Pandkar, Jharna Mishra, Neha Ahuja, Deepak Pant, Anna Cherian, Subhashis Natua, Cheemala Ashok, Narayanan S S Vishnu
Publikováno v:
NAR cancer
Hypoxic microenvironment heralds epithelial–mesenchymal transition (EMT), invasion and metastasis in solid tumors. Deregulation of alternative splicing (AS) of several cancer-associated genes has been instrumental in hypoxia-induced EMT. Our study
Publikováno v:
Journal of Cancer Research and Therapeutics. 18:224
Gliosarcoma (GS) has a low incidence but is aggressively invasive, with poor-survival. Even though GS is recognized as a different subgroup from glioblastoma (GB), there is no molecular panel available to define its clinical outcome. The objective wa
Autor:
Sanjeev Shukla, Rajendra Kumar Panday, Amit Gupta, Jharna Mishra, Atul Samaiya, Archana Pt, Sandhya Yadav
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 100(12)
The deregulation of splicing factors and alternative splicing are increasingly viewed as major contributory factors in tumorigenesis. In this study, we report overexpression of a key splicing factor, heterogeneous nuclear ribonucleoprotein A2B1 (HNRN
Publikováno v:
Journal of Evolution of Medical and Dental Sciences. 3:5190-5195
BACKGROUND AND AIMS: The study was done to know the accuracy of Triple assessment and management strategies for breast cancer patients. MATERIALS AND METHODS: Patients with carcinoma breast were analyzed in a tertiary care hospital of central India f
Publikováno v:
Journal of Evolution of Medical and Dental Sciences. 3:4956-4961
BACKGROUND AND AIMS: The study was done to know the epidemiology, clinicopathological aspects of carcinoma breast patients in our population. MATERIALS AND METHODS: The epidemiological and clinicopathological data pertaining to demography and risk fa