Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jhansi L. Leslie"'
Autor:
Md Jashim Uddin, Brandon Thompson, Jhansi L. Leslie, Casey Fishman, Katia Sol-church, Pankaj Kumar, William A. Petri
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Innate lymphoid cells (ILCs) play a critical role in maintaining intestinal health in homeostatic and diseased conditions. During Clostridium difficile infection (CDI), IL-33 activates ILC2 to protect from colonic damage and mortality. The f
Externí odkaz:
https://doaj.org/article/a9114d612dec4b05b683cdb7d721fb7b
Autor:
Nicholas A. Lesniak, Alyxandria M. Schubert, Kaitlin J. Flynn, Jhansi L. Leslie, Hamide Sinani, Ingrid L. Bergin, Vincent B. Young, Patrick D. Schloss
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The severity of Clostridioides difficile infections (CDI) has increased over the last few decades. Patient age, white blood cell count, and creatinine levels as well as C. difficile ribotype and toxin genes have been associated with disease
Externí odkaz:
https://doaj.org/article/8b8c8c2e674346f7938d7392dab27de3
Autor:
Matthew L. Jenior, Jhansi L. Leslie, Deborah A. Powers, Elizabeth M. Garrett, Kimberly A. Walker, Mary E. Dickenson, William A. Petri, Rita Tamayo, Jason A. Papin
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
ABSTRACT The pathogen Clostridioides difficile causes toxin-mediated diarrhea and is the leading cause of hospital-acquired infection in the United States. Due to growing antibiotic resistance and recurrent infection, targeting C. difficile metabolis
Externí odkaz:
https://doaj.org/article/25faa5a665f74d52badbf28e460eaa14
Autor:
Mayuresh M. Abhyankar, Mark T. Orr, Robert Kinsey, Sandra Sivananthan, Andrew J. Nafziger, David N. Oakland, Mary K. Young, Laura Farr, Md Jashim Uddin, Jhansi L. Leslie, Stacey L. Burgess, Hong Liang, Ines De Lima, Elise Larson, Jeffrey A. Guderian, Susan Lin, Aaron Kahn, Prakash Ghosh, Sierra Reed, Mark A. Tomai, Karl Pedersen, William A. Petri, Christopher B. Fox
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Amebiasis is a neglected tropical disease caused by Entamoeba histolytica. Although the disease burden varies geographically, amebiasis is estimated to account for some 55,000 deaths and millions of infections globally per year. Children and traveler
Externí odkaz:
https://doaj.org/article/27f8546d80654205a8c42df32dd87af3
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Autor:
Alyse L. Frisbee, Mahmoud M. Saleh, Mary K. Young, Jhansi L. Leslie, Morgan E. Simpson, Mayuresh M. Abhyankar, Carrie A. Cowardin, Jennie Z. Ma, Patcharin Pramoonjago, Stephen D. Turner, Alice P. Liou, Erica L. Buonomo, William A. Petri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Here, Frisbee et al. show that hypervirulent Clostridium difficile induces IL-33 expression in the gut and IL-33 reduces mortality and morbidity via group 2 innate lymphoid cells. Furthermore, serum levels of the soluble IL-33 decoy receptor, sST2, a
Externí odkaz:
https://doaj.org/article/8ea0571b5e634edeb6f07d5f54e6abfd
Autor:
Jhansi L. Leslie, Matthew L. Jenior, Kimberly C. Vendrov, Alexandra K. Standke, Madeline R. Barron, Tricia J. O’Brien, Lavinia Unverdorben, Pariyamon Thaprawat, Ingrid L. Bergin, Patrick D. Schloss, Vincent B. Young
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC. difficile
Externí odkaz:
https://doaj.org/article/8604af2ad47b4a479fe9703ad7454e38
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT Clostridium (Clostridioides) difficile, a Gram-positive, anaerobic bacterium, is the leading single cause of nosocomial infections in the United States. A major risk factor for Clostridium difficile infection (CDI) is prior exposure to antib
Externí odkaz:
https://doaj.org/article/d5acd46ecdab471fabdd0ee27a9c43c3
Publikováno v:
mSphere, Vol 3, Iss 3 (2018)
ABSTRACT Susceptibility to Clostridium difficile infection (CDI) is primarily associated with previous exposure to antibiotics, which compromise the structure and function of the gut bacterial community. Specific antibiotic classes correlate more str
Externí odkaz:
https://doaj.org/article/0403f747c60a4011b82638beadbfcd0a
Publikováno v:
mSystems, Vol 2, Iss 4 (2017)
ABSTRACT Clostridium difficile is the largest single cause of hospital-acquired infection in the United States. A major risk factor for Clostridium difficile infection (CDI) is prior exposure to antibiotics, as they disrupt the gut bacterial communit
Externí odkaz:
https://doaj.org/article/9344bc90bbc547699cbf618cb4bcd6ab
Autor:
Julio Revilla, William A. Petri, Noah Oakland, Jashim Uddin, Jhansi L. Leslie, Brandon L. Thompson, Pankaj Kumar, Alyse Frisbee, Stacey L. Burgess, Alexandra N. Donlan, Mayuresh M. Abhyankar
Publikováno v:
Mucosal Immunology
Entamoeba histolytica is a pathogenic protozoan parasite that causes intestinal colitis, diarrhea, and in some cases, liver abscess. Through transcriptomics analysis, we observed that E. histolytica infection was associated with increased expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b976cb432b080174301d1324099709
http://europepmc.org/articles/PMC8732277
http://europepmc.org/articles/PMC8732277