Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Jhang Ho Pak"'
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-16 (2024)
A bstract Background Clonorchis sinensis infection is one of the risk factors that provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis and even cholangiocarcinoma (CCA). Disrupted or aberrant intercellular communication among l
Externí odkaz:
https://doaj.org/article/0dadab177fcd497ab1358ce19d73f5ba
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291780 (2023)
The most common cause of sensorineural hearing loss is damage of auditory hair cells. Tumor necrosis factor-alpha (TNF-α) is closely associated with sensorineural hearing loss. The present study examined the preconditioning effect of dexamethasone (
Externí odkaz:
https://doaj.org/article/df58f02d45294707b6b2abcd95b88aef
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 11, p e0010909 (2022)
BackgroundClonorchis sinensis requires bile acid transporters as this fluke inhabits bile juice-filled biliary ducts, which provide an extreme environment. Clonorchis sinensis sodium-bile acid co-transporter (CsSBAT) is indispensable for the fluke's
Externí odkaz:
https://doaj.org/article/8f40f51a75de474f8aaa1c70fe13acb5
Autor:
Jung-Woong Kim, Junyeong Yi, Jinhong Park, Ji Hoon Jeong, Jinho Kim, Jihee Won, Seok Chung, Tong-Soo Kim, Jhang Ho Pak
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background Biliary tract infection with the carcinogenic human liver fluke, Clonorchis sinensis, provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma. Complications are proportional to the i
Externí odkaz:
https://doaj.org/article/98c3eaa22a1547fb9688377b7b213cea
Autor:
Pyo Yun Cho, Ji-Yun Lee, Tae Im Kim, Jin-Ho Song, Sung-Jong Hong, Won Gi Yoo, Takafumi Tsuboi, Kwon-Soo Ha, Jae-Wan Jung, Satoru Takeo, Eun-Taek Han, Banchob Sripa, Sung-Tae Hong, Jong-Yil Chai, Ho-Woo Nam, Jhang Ho Pak, Tong-Soo Kim
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008998 (2020)
Clonorchiasis caused by Clonorchis sinensis is endemic in East Asia; approximately 15 million people have been infected thus far. To diagnose the infection, serodiagnostic tests with excellent functionality should be performed. First, 607 expressed s
Externí odkaz:
https://doaj.org/article/c1804047a13446c38fbf2bfe20ce988d
Autor:
Fuhong Dai, Won Gi Yoo, Yanyan Lu, Jin-Ho Song, Ji-Yun Lee, Youngro Byun, Jhang Ho Pak, Woon-Mok Sohn, Sung-Jong Hong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008952 (2020)
The liver fluke Clonorchis sinensis inhabits the bile ducts, where bile concentration disparities across the fluke cell membrane can cause bile intoxication. Sodium-bile acid co-transporter (SBAT) plays a crucial role in bile acid recycling. The proc
Externí odkaz:
https://doaj.org/article/320c7254db2d405db997300d36727c87
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-11 (2017)
Abstract Background Multidrug resistance-associated protein 4 (MRP4) is a member of the C subfamily of the ABC family of ATP-binding cassette (ABC) transporters. MRP4 regulates ATP-dependent efflux of various organic anionic substrates and bile acids
Externí odkaz:
https://doaj.org/article/aa7549b4192e48008d8f833e99d2fdf1
Autor:
Jun-Won Chung, Su Young Kim, Hee Jung Park, Chang Su Chung, Hee Woo Lee, Sun Mi Lee, Inki Kim, Jhang Ho Pak, Gin Hyug Lee, Jin-Yong Jeong
Publikováno v:
Gut and Liver, Vol 11, Iss 5, Pp 648-654 (2017)
Background/AimsThe increased resistance of Helicobacter pylori to antibiotics has increased the need to develop new treatments for this bacterium. The aim of our study was to identify new drugs with anti-H. pylori activity.Methods : We screened a sma
Externí odkaz:
https://doaj.org/article/f1d27783b7364cbba52ad51f34f1fdee
Autor:
Jun-Won Chung, Seok Hoo Jeong, Sun Mi Lee, Jhang Ho Pak, Gin Hyug Lee, Jin-Yong Jeong, Jin-Ho Kim
Publikováno v:
Gut and Liver, Vol 11, Iss 3, Pp 392-400 (2017)
Background/AimsMicroRNAs (miRNAs) regulate gene expression. We assess miRNA regulation by Helicobacter pylori infection and elucidate their role in H. pylori-infected gastric epithelial cells.Methods : The relationship between miRNA expression and DN
Externí odkaz:
https://doaj.org/article/6e6fb37a4ee74b198957b5e0c83e3d31
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007818 (2019)
Clonorchis sinensis is a carcinogenic human liver fluke, prolonged infection which provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma (CCA). These effects are driven by direct physical damage cause
Externí odkaz:
https://doaj.org/article/79be62f18e55446eb6a20ab99411ce3a