Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jhana O. Hendrickx"'
Publikováno v:
International Journal of Translational Medicine, Vol 3, Iss 4, Pp 516-526 (2023)
Due to global population growth, age-related disorders like cardiovascular disease and dementia are anticipated to increase. Recent data suggests a connection between cardiovascular disease and neurodegeneration, especially focusing on arterial stiff
Externí odkaz:
https://doaj.org/article/0bdd1fa5e5564203bc17cc51c18f884c
Autor:
Sofie De Moudt, Jhana O. Hendrickx, Cédric Neutel, Dorien De Munck, Arthur Leloup, Guido R. Y. De Meyer, Wim Martinet, Paul Fransen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A 24-month aging study in male C57Bl/6 mice reveals that aortic aging precedes cardiovascular disease and is due to changes in the extracellular matrix and vascular smooth muscle cell signaling.
Externí odkaz:
https://doaj.org/article/a2bb32bb6972419eaf34a34dc3f2ae01
Publikováno v:
Physiological Reports, Vol 10, Iss 18, Pp n/a-n/a (2022)
Abstract In vivo angiotensin II (AngII)‐treatment is a widely used experimental model to induce cardiovascular disease and results in a high likelihood of abdominal aorta aneurysm (AAA) formation. This involves progressive and irreversible focal di
Externí odkaz:
https://doaj.org/article/e1c8f1cf7259472f85ca8f94b760f9dd
Autor:
Sofie De Moudt, Jhana O. Hendrickx, Cédric Neutel, Dorien De Munck, Arthur Leloup, Guido R.Y. De Meyer, Wim Martinet, Paul Fransen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction and Aims: Endothelial dysfunction is recognized as a cardiovascular aging hallmark. Administration of nitric oxide synthase blocker N-Ω-Nitro-L-arginine methyl ester hydrochloride (L-NAME) constitutes a well-known small animal model of
Externí odkaz:
https://doaj.org/article/fd241187897a452a96ebdb98142b7491
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction and Aims: Endothelial nitric oxide synthase (eNOS) knockout mice develop pronounced cardiovascular disease. In the present study, we describe the alterations in aortic physiology and biomechanics of eNOS knockout and C57Bl/6 control mice
Externí odkaz:
https://doaj.org/article/e11496c2222f43f7b9213192cca5d72a
Autor:
Paula Santos-Otte, Hanne Leysen, Jaana van Gastel, Jhana O. Hendrickx, Bronwen Martin, Stuart Maudsley
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1265-1277 (2019)
Aging is a complex biological process that is inevitable for nearly all organisms. Aging is the strongest risk factor for development of multiple neurodegenerative disorders, cancer and cardiovascular disorders. Age-related disease conditions are mai
Externí odkaz:
https://doaj.org/article/b817be3f565c41b19aa597b80d1164c2
Autor:
Jhana O. Hendrickx, Charlotte Adams, Anne Sieben, Kris Laukens, Debby Van Dam, Guido R. Y. De Meyer
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1772 (2022)
Nitric oxide (NO) is a small gaseous signaling molecule responsible for maintaining homeostasis in a myriad of tissues and molecular pathways in neurology and the cardiovasculature. In recent years, there has been increasing interest in the potential
Externí odkaz:
https://doaj.org/article/0c0bac3b60774483bbe457450f2b0b5c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The average age of the world’s elderly population is steadily increasing. This unprecedented rise in the aged world population will increase the prevalence of age-related disorders such as cardiovascular disease (CVD) and neurodegeneration. In rece
Externí odkaz:
https://doaj.org/article/a69b9ce9ea9b440294ad9a7343c51821
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Objective: Alzheimer’s disease (AD) is characterized by noticeable neuropsychiatric symptoms and cognitive decline [1]. In addition, cardiovascular disease (CVD) is a known etiological hallmark of AD pathogenesis [2]. Recent epidemiological evidenc
Externí odkaz:
https://doaj.org/article/1a600e3f06224ffdae05e2ac7064f0e5
Autor:
Sofie De Moudt, Jhana O. Hendrickx, Dorien G. De Munck, Arthur J. Leloup, Wim Martinet, Guido R.Y. De Meyer, Paul Fransen
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Background: Although generally assumed to be an adaptive response to increased blood pressure (BP), arterial stiffness is now recognized as an independent predictor of cardiovascular (CV) events [1]. Moreover it precedes hypertension in at least two
Externí odkaz:
https://doaj.org/article/cfeeade4118549608d02ee2d8eebc899