Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jh, Slingsby"'
Publikováno v:
Europe PubMed Central
Hereditary C1q deficiency is a rare disease and up to now only 41 cases have been reported. Since all but 3 cases developed SLE or SLE-like disease, C1q deficiency represents the most powerful disease susceptibility gene identified for the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d7ed8b773feac96b6b5cb43c65054ddc
https://pubmed.ncbi.nlm.nih.gov/10728448
https://pubmed.ncbi.nlm.nih.gov/10728448
Autor:
Elizabeth Simpson, SJ Rose, MA Maibaum, Michelle E. K. Haywood, MB Hogarth, Kevin A. Davies, Phillip Chandler, PJ Allen, Mark Walport, JH Slingsby, Bernard J Morley, EM Thompson
Publikováno v:
Arthritis and rheumatism. 43(2)
Objective To identify intervals containing systemic lupus erythematosus (SLE) susceptibility alleles in the BXSB strain of mice. Methods We analyzed 286 (B10 × [B10 × BXSB]F1) backcross mice for a range of phenotypic traits associated with the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdc715796613887d0976c7811fb37b2
https://pubmed.ncbi.nlm.nih.gov/10693874
https://pubmed.ncbi.nlm.nih.gov/10693874
Autor:
Glen Pearce, Peter J. Norsworthy, Bernard J Morley, Mark Walport, JH Slingsby, Helen Issler, Akshay K. Vaishnaw
Publikováno v:
Arthritis and rheumatism. 39(4)
Objective. To describe a new kindred with C1q deficiency and to identify the molecular lesions responsible for complete functional C1q deficiency in this and 2 other previously described kindreds. Methods. The A-, B-, and C-chain genes of C1q were am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a1c9228449a19d8db8c8d6c9b8456d
https://pubmed.ncbi.nlm.nih.gov/8630118
https://pubmed.ncbi.nlm.nih.gov/8630118
Publikováno v:
Europe PubMed Central
The C57BL/6 (B6) and C57BL/10 (B10) inbred mouse strains are among the most commonly used in biological research and have provided the genetic background for the construction of many congenic strains. The two substrains were derived from the parental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04128d4b453e17c5b54629d4fdc9cac9
https://doi.org/10.1007/bf00186607
https://doi.org/10.1007/bf00186607
Publikováno v:
Immunogenetics. 46:361-362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96faf9b073e62290d59e3fa274c4616
https://doi.org/10.1007/s002510050287
https://doi.org/10.1007/s002510050287
Publikováno v:
Mammalian Genome. 7:319-320
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ec4e6da4c563c1b62f1a95ab9eeec
https://doi.org/10.1007/s003359900091
https://doi.org/10.1007/s003359900091
Autor:
Umit Saatci, Michael J. Mihatsch, Rezan Topaloglu, JH Slingsby, M. Pascual, Mark Walport, Peter J. Norsworthy, Bernard J Morley, Aysin Bakkaloglu, J A Schifferli
Publikováno v:
Kidney International. (2):635-642
Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family. Two siblings (case 1 and case 2) with homozygous C1q deficiency are described. Both presented with a photosensitive rash, and during follow-up c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb55e46c761350cdbac6d95fbfa8065b
Autor:
Mb, Hogarth, Jh, Slingsby, Pj, Allen, Em, Thompson, Chandler P, Ka, Davies, Simpson E, Bj, Morley, Mark Walport
Publikováno v:
Europe PubMed Central
BXSB mice spontaneously develop a lupus-like syndrome that is accelerated by the Yaa gene (Y-linked autoimmune accelerator). We studied the phenotype of disease in (B10 x BXSB)F1 and (BXSB x (B10 x BXSB)F1) backcross mice and genotyped 224 backcross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a48919e6a00927a2136694025fd00a7e
http://europepmc.org/abstract/med/9743333
http://europepmc.org/abstract/med/9743333
Autor:
Slingsby JH; Oxford BioMedica (UK) Ltd, Medawar Centre., Baban D, Sutton J, Esapa M, Price T, Kingsman SM, Kingsman AJ, Slade A
Publikováno v:
Human gene therapy [Hum Gene Ther] 2000 Jul 01; Vol. 11 (10), pp. 1439-51.
Autor:
Haywood ME; Imperial College School of Medicine, London, UK., Hogarth MB, Slingsby JH, Rose SJ, Allen PJ, Thompson EM, Maibaum MA, Chandler P, Davies KA, Simpson E, Walport MJ, Morley BJ
Publikováno v:
Arthritis and rheumatism [Arthritis Rheum] 2000 Feb; Vol. 43 (2), pp. 349-55.