Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Jf, Apperley"'
Publikováno v:
Expert Review of Hematology. 16:325-332
Autor:
Jf, Apperley, Jones L, Geoff Hale, Waldmann H, Hows J, Rombos Y, Tsatalas C, Re, Marcus, Aw, Goolden, Ec, Gordon-Smith
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Between December 1983 and November 1985 we treated 39 patients with chronic myeloid leukaemia by chemoradiotherapy and transplantation from HLA-identical sibling donors using bone marrow that had been depleted of T cells ex vivo with the rat monoclon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7ed5684bf84873c0b2a392ff7cd6bbbc
https://ora.ox.ac.uk/objects/uuid:761495c9-c3d4-4fa2-ab18-17e0d5ddb0b1
https://ora.ox.ac.uk/objects/uuid:761495c9-c3d4-4fa2-ab18-17e0d5ddb0b1
Publikováno v:
European Journal of Haematology. 39:144-147
5 patients with chronic myeloid leukaemia (CML) have been treated by BMT from identical twin donors. Syngeneity of the twins was established by conventional methods in the first 2 patients. These included the similarity of phenotype, dermatoglyphics
Publikováno v:
Clinical & Laboratory Haematology. 14:127-130
Summary We describe a case of proven invasive pulmonary aspergillosis in a neutropenic patient in whom disease progression occurred during treatment with conventional amphotericin B despite neutrophil recovery. Treatment with liposomal encapsulated a
Publikováno v:
Blood. 86:4468-4473
The use of peripheral blood progenitor cells (PBPC) to reconstitute hematopoiesis after high-dose chemoradiotherapy is now commonplace in the treatment of malignancies. Attempts to characterize these cells have concentrated primarily on their phenoty
Autor:
JF Apperley
Publikováno v:
Baillière's Clinical Haematology. 6:299-325
Bone marrow transplantation (BMT) is the only treatment currently available which can cure thalassaemia and sickle cell anaemia. However, it is not without risk and the complications of graft failure, GVHD, veno-occlusive disease, interstitial pneumo
Autor:
EG Wright, Charles Craddock, Michael A. Evans, CA Bennett, LE Healy, MY Gordon, PG Grimsley, JF Apperley
Publikováno v:
Europe PubMed Central
Chemotherapy has been used clinically to mobilize hematopoietic progenitor cells into the peripheral blood so that they can be harvested for autologous transplantation. In humans, this is demonstrated by the presence of circulating granulocyte-macrop
Publikováno v:
The International Journal of Cell Cloning. 10:2-5
Studies in mice have shown that long-term marrow repopulating cells can be induced to circulate following treatment with cyclophosphamide. These cells can be harvested from the blood of treated mice and used as a transplant to rescue lethally irradia
Publikováno v:
Blood. 78:310-317
Retroviral-mediated gene transfer of human adenosine deaminase (hADA) provides a model system for the development of somatic gene therapy as a therapy for diseases of bone marrow-derived cells. We have previously demonstrated that hADA can be observe
Autor:
David R. Williams, JF Apperley
Publikováno v:
British Journal of Haematology. 75:148-155
The pluripotent stem cell is a rare cell, estimated to be approximately 0•001% of nucleated marrow cells (Harrison et al. 1988). Therefore, any method of introduction of exogenous DNA needs to be extremely efficient. To date recombinant retrovirus