Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel.

Autor: Bokhari RS; Agile Decision Sciences, NRESS, Arlington, VA 22202, United States of America. Electronic address: rbokhari@nasaprs.com., Beheshti A; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, United States of America; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, United States of America., Blutt SE; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, United States of America; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, United States of America., Bowles DE; Division of Surgical Sciences, Department of Surgery, Duke University, Durham NC, United States of America., Brenner D; Columbia University, New York, NY, 10027, United States of America., Britton R; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, United States of America., Bronk L; The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States of America., Cao X; Stanford University School of Medicine, Stanford, CA 94305, United States of America., Chatterjee A; Sachi Bioworks, Louisville, CO 80027, United States of America; University of Colorado Boulder, Boulder, CO 80303, United States of America., Clay DE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States of America., Courtney C; Sachi Bioworks, Louisville, CO 80027, United States of America., Fox DT; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States of America., Gaber MW; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States of America., Gerecht S; Chemical and Biomolecular Engineering and Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218 United States of America; Biomedical Engineering, Duke University, Durham, NC 27708, United States of America., Grabham P; Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 10027 United States of America., Grosshans D; The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States of America., Guan F; The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States of America., Jezuit EA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States of America., Kirsch DG; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States of America., Liu Z; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States of America; Jan and Dan Duncan Neurological Research Institute, 1250 Moursund St. Houston, TX 77030, United States of America., Maletic-Savatic M; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States of America; Jan and Dan Duncan Neurological Research Institute, 1250 Moursund St. Houston, TX 77030, United States of America., Miller KM; Department of Molecular Biosciences, The University of Texas, Austin, TX 78712, United States of America., Montague RA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States of America., Nagpal P; Sachi Bioworks, Louisville, CO 80027, United States of America., Osenberg S; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States of America; Jan and Dan Duncan Neurological Research Institute, 1250 Moursund St. Houston, TX 77030, United States of America., Parkitny L; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States of America; Jan and Dan Duncan Neurological Research Institute, 1250 Moursund St. Houston, TX 77030, United States of America., Pierce NA; Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States of America; Division of Engineering & Applied Science, California Institute of Technology, Pasadena, CA 91125, United States of America; Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom., Porada C; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program Wake Forest School of Medicine, Winston-Salem, NC 27157, United States of America., Rosenberg SM; Department of Molecular and Human Genetics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77303, United States of America; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77303, United States of America; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77303, United States of America; Department of Molecular Virology and Microbiology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77303, United States of America., Sargunas P; Chemical and Biomolecular Engineering and Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218 United States of America., Sharma S; Sachi Bioworks, Louisville, CO 80027, United States of America., Spangler J; Chemical and Biomolecular Engineering and Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218 United States of America., Tavakol DN; Columbia University, New York, NY, 10027, United States of America., Thomas D; Stanford University School of Medicine, Stanford, CA 94305, United States of America., Vunjak-Novakovic G; Columbia University, New York, NY, 10027, United States of America., Wang C; Division of Surgical Sciences, Department of Surgery, Duke University, Durham NC, United States of America., Whitcomb L; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, United States of America., Young DW; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030, United States of America., Donoviel D; Translational Research Institute for Space Health, Houston, TX 77030, United States of America; Center for Space Medicine, Baylor College of Medicine, Houston, TX 77030, United States of America. Electronic address: donoviel@bcm.edu.

Publikováno v: Life sciences in space research [Life Sci Space Res (Amst)] 2022 Nov; Vol. 35, pp. 105-112. Date of Electronic Publication: 2022 Aug 07.

Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation.

Autor: Clay DE; Department of Cell Biology, Duke University School of Medicine, Durham, NC., Bretscher HS; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC., Jezuit EA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC., Bush KB; University Program in Genetics and Genomics, Duke University School of Medicine, Durham, NC., Fox DT; Department of Cell Biology, Duke University School of Medicine, Durham, NC.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC.; University Program in Genetics and Genomics, Duke University School of Medicine, Durham, NC.

Publikováno v: The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Oct 06.