Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jez Huang"'
Autor:
Anna Jezierski, Jez Huang, Arsalan S. Haqqani, Julie Haukenfrers, Ziying Liu, Ewa Baumann, Caroline Sodja, Claudie Charlebois, Christie E. Delaney, Alexandra T. Star, Qing Liu, Danica B. Stanimirovic
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Blood brain barrier (BBB) models in vitro are an important tool to aid in the pre-clinical evaluation and selection of BBB-crossing therapeutics. Stem cell derived BBB models have recently demonstrated a substantial advantage over primary an
Externí odkaz:
https://doaj.org/article/80fa25998cc847f2a3c4935dc2ccbd5b
Autor:
Jez Huang, Ying Betty Li, Claudie Charlebois, Tina Nguyen, Ziying Liu, Darin Bloemberg, Ahmed Zafer, Ewa Baumann, Caroline Sodja, Sonia Leclerc, Gwen Fewell, Qing Liu, Balabhaskar Prabhakarpandian, Scott McComb, Danica B. Stanimirovic, Anna Jezierski
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Human blood brain barrier (BBB) models derived from induced pluripotent stem cells (iPSCs) have become an important tool for the discovery and preclinical evaluation of central nervous system (CNS) targeting cell and gene-based therapies. Ch
Externí odkaz:
https://doaj.org/article/d53305594e694de79d738dc205e52f5f
Autor:
Anna Jezierski, Jez Huang, Betty (Ying) Li, Claudie Charlebois, Tina Nguyen, Ziying Liu, Darin Bloemberg, Ahmed Zafer, Ewa Baumann, Caroline Sodja, Sonia Leclerc, Gwen Fewell, Qing Liu, Balabhaskar Prabhakarpandian, Scott McComb, Danica B. Stanimirovic
Human blood brain barrier (BBB) models derived from induced pluripotent stem cell (iPSC) have become an important tool for discovery and preclinical evaluation of central nervous system (CNS) targeting cell and gene-based therapies. Chimeric antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d930f7fe2945d57d9f3ebb16765cd200
https://doi.org/10.21203/rs.3.rs-1466429/v1
https://doi.org/10.21203/rs.3.rs-1466429/v1
Autor:
Claudie, Charlebois, Jez, Huang, Caroline, Sodja, Maria, Ribecco-Lutkiewicz, Ewa, Baumann, Danica B, Stanimirovic, Anna, Jezierski
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2454
The development of translational and predictive models in vitro for assessing blood-brain barrier (BBB) delivery has become an important requirement in preclinical testing of CNS-targeting therapeutics. Here we describe a directed monolayer different
Autor:
Anna Jezierski, Jez Huang, Caroline Sodja, Danica Stanimirovic, Maria Ribecco-Lutkiewicz, Ewa Baumann, Claudie Charlebois
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621189
The development of translational and predictive models in vitro for assessing blood-brain barrier (BBB) delivery has become an important requirement in preclinical testing of CNS-targeting therapeutics. Here we describe a directed monolayer different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea9380818b716f57171e6a8303e76002
https://doi.org/10.1007/7651_2021_393
https://doi.org/10.1007/7651_2021_393
Autor:
Marguerite Ball, Jez Huang, Anna Jezierski, Danica Stanimirovic, Marzia Martina, Mahmud Bani-Yaghoub, Julie Haukenfrers, Caroline Sodja, Qing Liu, Dao Ly, Maria Ribecco-Lutkiewicz, Peter Zachar, Arsalan S. Haqqani, Marina Rukhlova, Ewa Baumann
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
We have developed a renewable, scalable and transgene free human blood-brain barrier model, composed of brain endothelial cells (BECs), generated from human amniotic fluid derived induced pluripotent stem cells (AF-iPSC), which can also give rise to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3efd5684bf9b096f5f7e9dca85238e6
https://doi.org/10.1038/s41598-018-19522-8
https://doi.org/10.1038/s41598-018-19522-8
Autor:
Mary Taglienti, Glenda M. Wright, Michel G. Arsenault, Carlos Lopez-Mendez, Jonathan Spears, Alfonso Lopez, Dorota W. Wadowska, Martin Kann, David E. Sims, Jez Huang, Monique C. Saleh, Yuan Miao, Sunny Hartwig, Jacqueline Ho
Publikováno v:
Developmental Dynamics. 242:790-799
Background: The DNA-binding transcription factor Wilms' Tumor Suppressor-1 (WT1) plays an essential role in nephron progenitor differentiation during renal development. We previously used Wt1 chromatin-immunoprecipitation coupled to microarray (ChIP-
Autor:
Jez, Huang, Michel, Arsenault, Martin, Kann, Carlos, Lopez-Mendez, Monique, Saleh, Dorota, Wadowska, Mary, Taglienti, Jacqueline, Ho, Yuan, Miao, David, Sims, Jonathan, Spears, Alfonso, Lopez, Glenda, Wright, Sunny, Hartwig
Publikováno v:
Developmental Dynamics. 244:628-628
The DNA-binding transcription factor Wilms' Tumor Suppressor-1 (WT1) plays an essential role in nephron progenitor differentiation during renal development. We previously used Wt1 chromatin-immunoprecipitation coupled to microarray (ChIP-chip) to ide