Zobrazeno 1 - 10
of 459
pro vyhledávání: '"Jeyasekharan A"'
Autor:
Jayagopal, Aishwarya, Xue, Hansheng, He, Ziyang, Walsh, Robert J., Hariprasannan, Krishna Kumar, Tan, David Shao Peng, Tan, Tuan Zea, Pitt, Jason J., Jeyasekharan, Anand D., Rajan, Vaibhav
Cancer remains a global challenge due to its growing clinical and economic burden. Its uniquely personal manifestation, which makes treatment difficult, has fuelled the quest for personalized treatment strategies. Thus, genomic profiling is increasin
Externí odkaz:
http://arxiv.org/abs/2402.10551
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Confocal microscopy has evolved to be a widely adopted imaging technique in molecular biology and is frequently utilized to achieve accurate subcellular localization of proteins. Applying colocalization analysis on image z-stacks obtained from confoc
Externí odkaz:
https://doaj.org/article/fc6763c85852409e8ea369043dd28bb9
Autor:
Min Liu, Giorgio Bertolazzi, Shruti Sridhar, Rui Xue Lee, Patrick Jaynes, Kevin Mulder, Nicholas Syn, Michal Marek Hoppe, Shuangyi Fan, Yanfen Peng, Jocelyn Thng, Reiya Chua, Jayalakshmi, Yogeshini Batumalai, Sanjay De Mel, Limei Poon, Esther Hian Li Chan, Joanne Lee, Susan Swee-Shan Hue, Sheng-Tsung Chang, Shih-Sung Chuang, K. George Chandy, Xiaofei Ye, Qiang Pan-Hammarström, Florent Ginhoux, Yen Lin Chee, Siok-Bian Ng, Claudio Tripodo, Anand D. Jeyasekharan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Macrophages are abundant immune cells in the microenvironment of diffuse large B-cell lymphoma (DLBCL). Macrophage estimation by immunohistochemistry shows varying prognostic significance across studies in DLBCL, and does not provide a compr
Externí odkaz:
https://doaj.org/article/dcc5aed0ca7744c29e4e5d657125614a
Autor:
Wee-Lee Chan, Vanessa Cui Lian Chong, Ian Jun Yan Wee, Li Mei Poon, Esther Hian Lee Chan, Joanne Lee, Yen-Lin Chee, Anand D. Jeyasekharan, Wee-Joo Chng, Miny Samuel, Sanjay de Mel
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rituximab-based chemo-immunotherapy is currently the standard first-line treatment for Waldenstrom macroglobulinaemia (WM), while ibrutinib has emerged as an alternative. In the absence of randomised trials (RCTs) comparing these regimens, t
Externí odkaz:
https://doaj.org/article/ff40f63f9b554a7eb8b5c591b218190b
Autor:
Jason Yongsheng Chan, Nagavalli Somasundaram, Nicholas Grigoropoulos, Francesca Lim, Michelle Limei Poon, Anand Jeyasekharan, Kheng Wei Yeoh, Daryl Tan, Georg Lenz, Choon Kiat Ong, Soon Thye Lim
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Diffuse large B-cell lymphoma (DLBCL) represents the commonest subtype of non-Hodgkin lymphoma and encompasses a group of diverse disease entities, each harboring unique molecular and clinico-pathological features. The understanding of the m
Externí odkaz:
https://doaj.org/article/267c944bf41a4e7c9eaee1dd7f218790
Autor:
Sanjay De Mel, Ainsley Ryan Lee, Joelle Hwee Inn Tan, Rachel Zi Yi Tan, Li Mei Poon, Esther Chan, Joanne Lee, Yen Lin Chee, Satish R. Lakshminarasappa, Patrick William Jaynes, Anand D. Jeyasekharan
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Deregulation of the DNA damage response (DDR) plays a critical role in the pathogenesis and progression of many cancers. The dependency of certain cancers on DDR pathways has enabled exploitation of such through synthetically lethal relationships e.g
Externí odkaz:
https://doaj.org/article/0056804496884dc7b3aedeaea78620e9
Akademický článek
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Autor:
Jianbiao Zhou, Sabrina Hui-Min Toh, Tze King Tan, Kalpnaa Balan, Jing Quan Lim, Tuan Zea Tan, Sinan Xiong, Yunlu Jia, Siok-Bian Ng, Yanfen Peng, Anand D. Jeyasekharan, Shuangyi Fan, Soon Thye Lim, Chin-Ann Johnny Ong, Choon Kiat Ong, Takaomi Sanda, Wee-Joo Chng
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-20 (2023)
Abstract Background Extranodal natural killer/T-cell lymphoma (NKTL) is an aggressive type of non-Hodgkin lymphoma with dismal outcome. A better understanding of disease biology and key oncogenic process is necessary for the development of targeted t
Externí odkaz:
https://doaj.org/article/846e95d9de9a442a8d6a7330386245b8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Bhav Harshad Parikh, Zengping Liu, Paul Blakeley, Qianyu Lin, Malay Singh, Jun Yi Ong, Kim Han Ho, Joel Weijia Lai, Hanumakumar Bogireddi, Kim Chi Tran, Jason Y. C. Lim, Kun Xue, Abdurrahmaan Al-Mubaarak, Binxia Yang, Sowmiya R, Kakkad Regha, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Zhongxing Zhang, Anand D. Jeyasekharan, Veluchamy Amutha Barathi, Weimiao Yu, Kang Hao Cheong, Timothy A. Blenkinsop, Walter Hunziker, Gopal Lingam, Xian Jun Loh, Xinyi Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
One common cause of vision loss after retinal detachment surgery is retinal scarring. Here the authors demonstrate that a bio-functional polymer can prevent retinal scarring by suppression of epithelial-mesenchymal transition and hyper-proliferation
Externí odkaz:
https://doaj.org/article/29658a3e9704480d80f0623a65432050