Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeyarani Regunathan"'
Autor:
Wendy Demos, D.V. Bosenko, Yashu Vashishath, Maryam Yassai, Vivian Zhou, Fong Lee, Jeyarani Regunathan, Jodie Box, Jack Gorski
Publikováno v:
Human Immunology. 74:809-817
The CD8 memory T cell repertoire to the influenza A derived M1(58-66) epitope shows a restricted V genes and CDR3 sequences usage. The repertoire is highly polyclonal and the clonotype distribution has been described as consisting of two components,
Autor:
Snjezana Kutlesa, Renren Wen, Li Bai, Jeyarani Regunathan, Yuhong Chen, Subramaniam Malarkannan, Xuezhi Dai, Demin Wang
Publikováno v:
The Journal of Immunology. 177:5365-5376
NK cells play a central role in mediating innate immune responses. Activation of NK cells results in cytotoxicity, cytokine, and chemokine secretions. In this study, we show that in mice with targeted deletion of phospholipase Cγ (PLCγ)2, one of th
Publikováno v:
Clinical and Applied Immunology Reviews. 5:95-109
Even after matching the alleles for the major histocompatibility complexes (MHC), grafts are rejected in a considerable percentage of transplant recipients by the host immune system. In these patients, the host T cells recognize unique antigenic pept
Publikováno v:
Blood. 105:233-240
Interaction of the activating ligand H60 with NKG2D receptor constitutes a major stimulatory pathway for natural killer (NK) cells. The influence of inhibitory Ly49 receptors on NKG2D-mediated activation is not clearly understood. Here we show that t
Autor:
Snjezana Kutlesa, Renren Wen, Subramaniam Malarkannan, Jeyarani Regunathan, Demin Wang, Hu Zeng, Yuhong Chen, Haiyan Chu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(6)
Activating receptors such as NKG2D and Ly49D mediate a multitude of effector functions including cytotoxicity and cytokine generation in NK cells. However, specific signaling events that are responsible for the divergence of distinct effector functio