Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeyapriya Rajameenakshi Sundaram"'
Autor:
Murni Tio, Rujing Wen, Cai Ning Choo, Jian Bin Tan, Aaron Chua, Bin Xiao, Jeyapriya Rajameenakshi Sundaram, Christine Hui Shan Chan, Eng-King Tan
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-23 (2024)
Abstract Background Mutations in CHCHD2 have been linked to Parkinson’s disease, however, their exact pathophysiologic roles are unclear. The p32 protein has been suggested to interact with CHCHD2, however, the physiological functions of such inter
Externí odkaz:
https://doaj.org/article/6b0c5e5c904f4378a64375f261a25084
Autor:
Shirish Shenolikar, Mahmood Ahmed, Simi Elizabeth George, Jeyapriya Rajameenakshi Sundaram, Sujoy Ghosh, Yilong Wu, Irene Chengjie Lee, Sashi Kesavapany, Monalisa Hota, Eng-King Tan
Publikováno v:
ACS Chemical Neuroscience. 10:3575-3589
Guanabenz (GBZ), an α2-adrenergic agonist, demonstrated off-target effects that restored protein homeostasis and ameliorated pathobiology in experimental models of neurodegenerative disease. However, GBZ did not directly activate the integrated stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b186c494663a8bb70013982a33a24ee
https://doi.org/10.1021/acschemneuro.9b00185
https://doi.org/10.1021/acschemneuro.9b00185
Autor:
Shirish Shenolikar, Simi Elizabeth George, Karen Ka Lam Pang, Xue Yan Ho, Permeen Yusoff, Weiwei Luo, Irene Chengjie Lee, Jeyapriya Rajameenakshi Sundaram, Catherine Wenhui Goh, Newman Siu Kwan Sze
Publikováno v:
Cell Death & Differentiation. 25:255-267
Phosphorylation of the eukaryotic translation initiation factor, eIF2α, by stress-activated protein kinases and dephosphorylation by the growth arrest and DNA damage-inducible protein (GADD34)-containing phosphatase is a central node in the integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c4eeb45edf90d5f691d61a948891bb
https://doi.org/10.1038/cdd.2017.152
https://doi.org/10.1038/cdd.2017.152
Autor:
Jeyapriya Rajameenakshi Sundaram, Yilong Wu, Irene Cheng Jie Lee, Simi Elizabeth George, Monalisa Hota, Sujoy Ghosh, Sashi Kesavapany, Mahmood Ahmed, Shirish Shenolikar
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df57154c174a5deb47a498e3c213ddb4
https://doi.org/10.2139/ssrn.3279414
https://doi.org/10.2139/ssrn.3279414
Autor:
Matthew H. Brush, Newman Siu Kwan Sze, Catherine Wenhui Goh, Irene Chengjie Lee, Permeen Yusoff, Simi Elizabeth George, Jeyapriya Rajameenakshi Sundaram, Shirish Shenolikar
Publikováno v:
The Journal of biological chemistry. 293(1)
Oxidative and endoplasmic reticulum (ER) stresses are hallmarks of the pathophysiology of ALS and other neurodegenerative diseases. In these stresses, different kinases phosphorylate eukaryotic initiation factor eIF2α, enabling the translation of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc71fcc93f810b092211ed88a002422
https://pubmed.ncbi.nlm.nih.gov/29109149
https://pubmed.ncbi.nlm.nih.gov/29109149