Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jeyantt S. Sankaran"'
Publikováno v:
Exp Biol Med (Maywood)
Bone marrow mesenchymal stem cells exist in a multipotential state, where osteogenic and adipogenic genomes are silenced in heterochromatin at the inner nuclear leaflet. Physical force, generated in the marrow space during dynamic exercise exerts con
Autor:
John Simonsen, Stefan Judex, Behzad Farshid, Balaji Sitharaman, Jeyantt S. Sankaran, M. Mohammadi, Gaurav Lalwani, Sunny C. Patel
Publikováno v:
Journal of Biomedical Materials Research Part A. 107:1143-1153
This study investigates the mechanical properties and in vitro cytotoxicity of two-dimensional (2D) graphene oxide nanoribbons and nanoplatelets (GONRs and GONPs) reinforced porous polymeric nanocomposites. Highly porous poly(propylene fumarate) (PPF
Autor:
Kenneth L. Seldeen, Bruce R. Troen, Alexander Jacob, Ramkumar Thiyagarajan, Jeyantt S. Sankaran, Richard J. Quigg, Stefan Judex, Jessy J. Alexander
Publikováno v:
Immunobiology. 223:761-771
Complement system is an important arm of the immune system that promotes inflammation. Complement Factor H (FH) is a critical regulator of the alternative complement pathway. Its absence causes pathology in different organs resulting in diseases such
Autor:
Sarah E. Little-Letsinger, Zhihui Xie, Maya Styner, Cody McGrath, Amel Dudakovic, Janet Rubin, Buer Sen, Andre J. van Wijnen, Jeyantt S. Sankaran
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
Use of the selective estrogen receptor modulator Tamoxifen (TAM) is a mainstay to induce conditional expression of Cre recombinase in transgenic laboratory mice. To excise β‐cateninfl/fl in 28‐day‐old male and female Prrx1‐CreER/β‐catenin
Autor:
Buer Sen, Janet Rubin, Amel Dudakovic, Cody McGrath, Zhihui Xie, Maya Styner, Sarah E. Little-Letsinger, Andre J. Wijnen, Jeyantt S. Sankaran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113879552003d8b8b5b250c94503ebe8
https://doi.org/10.1002/jbm4.10450/v2/response1
https://doi.org/10.1002/jbm4.10450/v2/response1
Autor:
Amel Dudakovic, Buer Sen, Zhihui Xie, Maya Styner, Janet Rubin, Gunes Uzer, Jeyantt S. Sankaran, Christopher R. Paradise, Andre J. van Wijnen, Mark B. Meyer
Publikováno v:
J Bone Miner Res
During bone marrow stromal cell (BMSC) differentiation, both Wnt signaling and the development of a rigid cytoskeleton promote commitment to the osteoblastic over adipogenic lineage. β-catenin plays a critical role in the Wnt signaling pathway to fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6475b29ee64c0d23d1af8104102b6475
https://europepmc.org/articles/PMC7295671/
https://europepmc.org/articles/PMC7295671/
Autor:
Amel Dudakovic, Christopher R. Paradise, Buer Sen, Jeyantt S. Sankaran, Tony D. Perdue, Zhihui Xie, Maya Styner, Cody McGrath, Joshua Newberg, Janet Rubin, Gunes Uzer, Andre J. van Wijnen
Publikováno v:
Stem Cells
Nuclear actin plays a critical role in mediating mesenchymal stem cell (MSC) fate commitment. In marrow-derived MSCs, the principal diaphanous-related formin Diaph3 (mDia2) is present in the nucleus and regulates intranuclear actin polymerization, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6445e3d143f9523b45125071e6d169cf
https://europepmc.org/articles/PMC6993926/
https://europepmc.org/articles/PMC6993926/
Autor:
Jeyantt S. Sankaran, Cody McGrath, Xiaopeng Zong, Negin Misaghian-Xanthos, Janet Rubin, Buer Sen, Zhihui Xie, Maya Styner, Martin Styner
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Marrow adipose tissue (MAT) and its relevance to skeletal health during caloric restriction (CR) is unknown: It remains unclear whether exercise, which is anabolic to bone in a calorie-replete state, alters bone or MAT in CR. We hypothesized that res
Publikováno v:
Mammalian Genome. 27:47-61
Genetic variations mediate skeletal responsiveness to mechanical unloading, with individual space travelers exhibiting large variations in the extent of bone loss. We previously identified genomic regions harboring several hundred genes that can modu
Autor:
Yi-Xian Qin, Gaurav Lalwani, Stefan Judex, Anu Gopalan, Jeyantt S. Sankaran, Balaji Sitharaman, Michael D'Agati
Publikováno v:
Journal of Biomedical Materials Research Part A. 103:3212-3225
Assembly of carbon nanomaterials into three-dimensional (3D) architectures is necessary to harness their unique physiochemical properties for tissue engineering and regenerative medicine applications. Herein, we report the fabrication and comprehensi