Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jewell A Jessup"'
Autor:
Hao Wang, Jewell A Jessup, Zhuo Zhao, Jaqueline Da Silva, Marina Lin, Lindsay M MacNamara, Sarfaraz Ahmad, Mark C Chappell, Carlos M Ferrario, Leanne Groban
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76992 (2013)
The cardioprotective effects of estrogen are well recognized, but the mechanisms remain poorly understood. Accumulating evidence suggests that the local cardiac renin-angiotensin system (RAS) is involved in the development and progression of cardiac
Externí odkaz:
https://doaj.org/article/65e7f4be3740476287dda48d4baafc8d
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15433 (2010)
The G protein-coupled estrogen receptor (GPER) is expressed in various tissues including the heart. Since the mRen2.Lewis strain exhibits salt-dependent hypertension and early diastolic dysfunction, we assessed the effects of the GPER agonist (G-1, 4
Externí odkaz:
https://doaj.org/article/59915d7559204d8883c1de12ade2acc2
Publikováno v:
Therapeutic Advances in Cardiovascular Disease. 3:245-257
Background: Hypertension and left ventricular (LV) hypertrophy often precede diastolic dysfunction and are risk factors for diastolic heart failure. Although pharmacologic inhibition of the renin-angiotensin system (RAS) improves diastolic function a
Publikováno v:
Journal of Molecular Medicine
Accumulation of a large body of evidence during the past two decades testifies to the complexity of the renin–angiotensin system (RAS). The incorporation of novel enzymatic pathways, resulting peptides, and their corresponding receptors into the bi
Autor:
Jewell A. Jessup, K. Bridget Brosnihan, Mark C. Chappell, Patricia E. Gallagher, Carlos M. Ferrario, David B. Averill, Ronald D. Smith, E. Ann Tallant
Publikováno v:
Kidney International. 68(5):2189-2196
Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Background Angiotensin-converting enzyme (ACE)2, a homologue of ACE, which is insensitive to ACE inhibitors and forms angiotensin-(1-7) [Ang-(1-7)]
Autor:
Sherry Vinsant, Jewell A. Jessup, David B. Averill, Patricia E. Gallagher, Susan M. Bosch, Brian M. Westwood, Debra I. Diz
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 29:473-482
1. The present review provides an update on evidence of the neurotransmitter pathways and location of receptors within the nucleus tractus solitarii (NTS) mediating the baroreflex and other haemodynamic actions of angiotensin (Ang) II. 2. A series of
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 306(5)
The prevalence of left ventricular diastolic dysfunction (LVDD) sharply increases in women after menopause and may lead to heart failure. While evidence suggests that estrogens protect the premenopausal heart from hypertension and ventricular remodel
Background: Knowledge of hemodynamic factors accounting for the development of hypertension should help to tailor therapeutic approaches and improve blood pressure control. Few data exist regarding sex differences of hemodynamic factors contributing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0849297a23706434913f0b5c474e7030
https://europepmc.org/articles/PMC4280797/
https://europepmc.org/articles/PMC4280797/
Autor:
Alex F. Chen, Lili Zhang, Jewell A. Jessup, Daniel B. Kim-Shapiro, Leanne Groban, Lindsay M. MacNamara, Hao Wang, Tennille D. Presley
OBJECTIVE mRen2.Lewis rats exhibit exacerbated increases in blood pressure, left ventricular (LV) remodeling, and diastolic impairment after the loss of estrogens. In this same model, depletion of estrogens has marked effects on the cardiac biopterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb46260e1dbf5c41cf588f52ce8e7cb9
https://europepmc.org/articles/PMC3690139/
https://europepmc.org/articles/PMC3690139/
Autor:
Carlos M. Ferrario, Sarfaraz Ahmad, Jaqueline da Silva, Marina Lin, Mark C. Chappell, Jewell A. Jessup, Zhuo Zhao, Leanne Groban, Lindsay M. MacNamara, Hao Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76992 (2013)
PLoS ONE
PLoS ONE
The cardioprotective effects of estrogen are well recognized, but the mechanisms remain poorly understood. Accumulating evidence suggests that the local cardiac renin-angiotensin system (RAS) is involved in the development and progression of cardiac