Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Jevtić Ivana I."'
1
Akademický článek
Synthesis, computational and pharmacological evaluation of novel N-{4-[2-(4-aryl-piperazin-1-yl)ethyl]phenyl}-arylamides
Autor: Andrić Deana B., Dukić-Stefanović Slađana, Krunić Mihajlo J., Jevtić Ivana I., Penjišević Jelena Z., Šukalović Vladimir B., Kostić-Rajačić Slađana
Publikováno v: Journal of the Serbian Chemical Society, Vol 89, Iss 3, Pp 291-303 (2024)
Serotonin, or 5-hydroxytryptamine (5-HT), is a biogenic amine most noted as a neurotransmitter, an activator of the utmost subtype family of G-protein- coupled receptors (GPCR). Drugs targeting 5-HT1A and other 5-HT receptors treat central nervous sy
Externí odkaz: https://doaj.org/article/47afa94e4ac443949c6748901a92f248
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2
Akademický článek
Antidiabetic potential of simple carbamate derivatives: Comparative experimental and computational study
Autor: Suručić Relja V., Jevtić Ivana I., Stanojković Tatjana P., Popović-Đorđević Jelena B.
Publikováno v: Journal of the Serbian Chemical Society, Vol 88, Iss 11, Pp 1089-1102 (2023)
With the increasing global burden of diabetes mellitus type 2, the search for the new drugs, with better pharmacological profile is continued. As a part of this surge, the synthesis, pharmacological in vitro and computational evaluation of five, simp
Externí odkaz: https://doaj.org/article/5d75f104217845ffb0e1b41784c2aef9
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3
Akademický článek
Synthetic route towards 1,2,3,4-tetrahydroquinoxaline/piperidine combined tricyclic ring system
Autor: Krunić Mihajlo J., Jevtić Ivana I., Penjišević Jelena Z., Kostić-Rajačić Slađana V.
Publikováno v: Journal of the Serbian Chemical Society, Vol 87, Iss 2, Pp 169-179 (2022)
The synthetic route toward novel tricyclic, nitrogen-containing system is disclosed. Three novel compounds possessing structural features of 1,2,3,4-tetrahydroquinoxaline and decahydropyrido[3,4-b]pyrazine are synthesized starting from readily availa
Externí odkaz: https://doaj.org/article/73e0c8fddc53408eb5c2b4bdfffbdf1d
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4
Akademický článek
μ-opioid/D2 dopamine receptor pharmacophore containing ligands: Synthesis and pharmacological evaluation
Autor: Jevtić Ivana I., Penjišević Jelena Z., Savić-Vujović Katarina R., Srebro Dragana P., Vučković Sonja M., Ivanović Milovan D., Kostić-Rajačić Slađana V.
Publikováno v: Journal of the Serbian Chemical Society, Vol 85, Iss 6, Pp 711-720 (2020)
Herein, the synthesis and pharmacological evaluation of 13 novel compounds, designed as potential heterobivalent ligands for μ-opioid receptor (MOR) and dopamine D2 receptors (D2DAR), are reported. The compounds consisted of anilido piperidine and N
Externí odkaz: https://doaj.org/article/9a224bd97bb9405aab39da7b126ece23
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5
Akademický článek
Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores
Autor: Jevtić Ivana I., Penjišević Jelena Z., Ivanović Milovan D., Kostić-Rajačić Slađana V.
Publikováno v: Journal of the Serbian Chemical Society, Vol 84, Iss 7, Pp 639-647 (2019)
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene g
Externí odkaz: https://doaj.org/article/1bc32f98f1f44fa199620f2d1c4f97b2
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8
Akademický článek
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10
Structure-activity relationship, docking analysis and ADME properties of newly designed, potent serotonin 5HT1a receptor ligands
Autor: Jevtić, Ivana I., Andrić, Deana, Penjišević, Jelena, Šukalović, Vladimir, Dukić-Stefanović, Slađana, Kostić-Rajačić, Slađana
Publikováno v: Book of abstracts-EFMC-YMCS-Young Medicinal Chemists' Symposium, September 8-9, 2022, Nice, France
EFMC-YMCS Young Medicinal Chemists' Symposium, Nica, France
Serotonin 5HT1a receptors belongs to a class G-protein coupled receptors and it is widely recognized as one of the targets for treating neurological disorders such depression and schizophrenia. N-arylpiperazine structural motif is present in many com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a7be05db756ea396732296b6ba4e9a54
https://cer.ihtm.bg.ac.rs/handle/123456789/5851
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