Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jevgenija Jakubovska"'
Autor:
Justina Medžiūnė, Žana Kapustina, Simona Žeimytė, Jevgenija Jakubovska, Rūta Sindikevičienė, Inga Čikotienė, Arvydas Lubys
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-8 (2022)
Next-generation genome sequencing technologies have revolutionized the life sciences, however all sequencing platforms require nucleic acid pre-processing to generate suitable libraries for sequencing. Here, oligonucleotide-tethered 2′,3′-dideoxy
Externí odkaz:
https://doaj.org/article/09a7f1459d2b4510aad2f930f1d56135
Autor:
Vida Časaitė, Mikas Sadauskas, Justas Vaitekūnas, Renata Gasparavičiūtė, Rita Meškienė, Izabelė Skikaitė, Mantas Sakalauskas, Jevgenija Jakubovska, Daiva Tauraitė, Rolandas Meškys
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 8, Pp n/a-n/a (2019)
Abstract Here, we present a proof‐of‐principle for a new high‐throughput functional screening of metagenomic libraries for the selection of enzymes with different activities, predetermined by the substrate being used. By this approach, a total
Externí odkaz:
https://doaj.org/article/ec7f509282114674ba255b5cbbde38f8
Publikováno v:
ChemBioChem. 20:2504-2512
A set of five N4 -acyl-modified 2'-deoxycytidine 5'-triphosphates were incorporated into modified DNA by using phi29 DNA polymerase, and cleavage by selected restriction endonucleases was studied. Modified DNA containing N4 -acyl functional groups in
Publikováno v:
Nucleic acids research, Oxford : Oxford University Press, 2018, vol. 46, iss. 12, p. 5911-5923
Nucleic Acids Research
Nucleic Acids Research
A huge diversity of modified nucleobases is used as a tool for studying DNA and RNA. Due to practical reasons, the most suitable positions for modifications are C5 of pyrimidines and C7 of purines. Unfortunately, by using these two positions only, on
Autor:
Rolandas Meškys, Daiva Tauraitė, Mikas Sadauskas, Rita Meškienė, Jevgenija Jakubovska, Mantas Sakalauskas, Vida Časaitė, Justas Vaitekūnas, Izabelė Skikaitė, Renata Gasparavičiūtė
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 8, Pp n/a-n/a (2019)
MicrobiologyOpen
MicrobiologyOpen, Hoboken : Wiley, 2019, vol. 8, no. 8, art. no. e795, p. [1-15]
MicrobiologyOpen
MicrobiologyOpen, Hoboken : Wiley, 2019, vol. 8, no. 8, art. no. e795, p. [1-15]
Here, we present a proof‐of‐principle for a new high‐throughput functional screening of metagenomic libraries for the selection of enzymes with different activities, predetermined by the substrate being used. By this approach, a total of 21 enz
Publikováno v:
Chembiochem : a European journal of chemical biology. 20(19)
A set of five N
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific reports, London : Nature Publishing Group, 2018, vol. 8, art. no. 16484, p. [1-10]
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific reports, London : Nature Publishing Group, 2018, vol. 8, art. no. 16484, p. [1-10]
Bioconjugation, biosensing, bioimaging, bionanomaterials, etc., are only a few examples of application of functionalized DNA. Since base-modified nucleic acids contribute not only to a broad range of biotechnological fields but also to the understand
Autor:
Maksim Bratchikov, Julija Dabužinskaitė, Rolandas Meškys, Jevgenija Jakubovska, Daiva Tauraitė
Publikováno v:
Molecules, Basel : MDPIAG, 2017, Vol. 22, no 4, Art. no 672, Art. no 672p. 1-16
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
The synthesis of novel modified nucleotides and their incorporation into DNA sequences opens many possibilities to change the chemical properties of oligonucleotides (ONs), and, therefore, broaden the field of practical applications of modified DNA.