Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Jevgenij A. Raskatov"'
Supplementary Tables 1 and 2 from An HRE-Binding Py-Im Polyamide Impairs Hypoxic Signaling in Tumors
Supplementary Table 1: Primers used in RT-qPCR experiments; Supplementary Table 2: Percent changes in transcript expression of U251 tumors dosed with 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696a7853d2b9fc0bbb22071b26801a86
https://doi.org/10.1158/1535-7163.22508529
https://doi.org/10.1158/1535-7163.22508529
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 43K, Structures of Py-Im polyamides used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9d01537fd73ab03a001cb84685a117
https://doi.org/10.1158/1535-7163.22497396.v1
https://doi.org/10.1158/1535-7163.22497396.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 98K, Supplementary Figure and Table Captions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21af5a5ebf46ea2b5c0581782d41f6e0
https://doi.org/10.1158/1535-7163.22497372.v1
https://doi.org/10.1158/1535-7163.22497372.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 45K, Table of genes up- or down- regulated by 2- and 4- fold by E2 or 1 (1.0 �M), with FPKM > 20.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1c0fa87f0228c7047d832e942a0ec7
https://doi.org/10.1158/1535-7163.22497369.v1
https://doi.org/10.1158/1535-7163.22497369.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 16K, qRT-PCR analysis of Tff1 mRNA reduction after treatment with 1 for 96h is dose responsive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf2b464040df0c61be2f4515b0275bc
https://doi.org/10.1158/1535-7163.22497390
https://doi.org/10.1158/1535-7163.22497390
Supplementary Figure 1: Whole transcriptome analysis of U251 cells dosed with DFO and compounds 1 and 3; Supplementary Figure 2: Preliminary in vivo experiments - quantification of an uptake within of a radiolabeled Py-Im polyamide within tissues and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b492a0761958144e4a0c4c9195a091e5
https://doi.org/10.1158/1535-7163.22508532.v1
https://doi.org/10.1158/1535-7163.22508532.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 31K, Relative mRNA of E2 induced tff1 in the presence of 1 at 2 �M.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982733b01d9199f0546d645d4946877e
https://doi.org/10.1158/1535-7163.22497384.v1
https://doi.org/10.1158/1535-7163.22497384.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 24K, Serum concentrations of 1 after subcutaneous injection (120 nmol) into C57BL/6 mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277bbc3615dc79195d6debee5f3d92e5
https://doi.org/10.1158/1535-7163.22497381
https://doi.org/10.1158/1535-7163.22497381
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 43K, Comparison of cytotoxicity of 1 between T47D-KBLuc and ER-� negative cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f44011e3470d2f5a822eaab4d0fe12
https://doi.org/10.1158/1535-7163.22497387.v1
https://doi.org/10.1158/1535-7163.22497387.v1
Autor:
Peter B. Dervan, Jevgenij A. Raskatov, Benjamin C. Li, Amanda E. Hargrove, Jerzy O. Szablowski, Nicholas G. Nickols
PDF File - 241K, Genes affected at least 2-fold by polyamide (1 �M) and unaffected by E2 addition were analyzed using BP_FAT GO term on the DAVID functional annotation tool.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7b69289e70727b12606fecfbff9271
https://doi.org/10.1158/1535-7163.22497363.v1
https://doi.org/10.1158/1535-7163.22497363.v1