Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jeungphill Hanne"'
Autor:
Jiaquan Liu, Ryanggeun Lee, Brooke M. Britton, James A. London, Keunsang Yang, Jeungphill Hanne, Jong-Bong Lee, Richard Fishel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The mechanics of MMR strand specific excision that begins at a distant ssDNA break are not yet clear. Here the authors have used multiple single molecule imaging techniques to visualize the behavior of MMR components on mismatched DNA substrates and
Externí odkaz:
https://doaj.org/article/903ba956ff58487c9fce0df21e9181e3
Autor:
Nathan D. Jones, Miguel A. Lopez Jr, Jeungphill Hanne, Mitchell B. Peake, Jong-Bong Lee, Richard Fishel, Kristine E. Yoder
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Retroviral Integration into the host DNA is a rare event with evidence suggesting that it relies on DNA topology and sequence. Here the authors present single molecule evidence that shows the retroviral integration machinery vigorously scans the targ
Externí odkaz:
https://doaj.org/article/4c0178fb357c4b6c9e3c7ff0e81765af
Autor:
Geoffrey R Bennett, Ryan Peters, Xiao-hong Wang, Jeungphill Hanne, Robert W Sobol, Ralf Bundschuh, Richard Fishel, Kristine E Yoder
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103164 (2014)
Host base excision repair (BER) proteins that repair oxidative damage enhance HIV infection. These proteins include the oxidative DNA damage glycosylases 8-oxo-guanine DNA glycosylase (OGG1) and mutY homolog (MYH) as well as DNA polymerase beta (Pol
Externí odkaz:
https://doaj.org/article/356ae06ec6874e5ca4223e0fa58c37a7
Autor:
Jeungphill Hanne, Brooke M. Britton, Jonghyun Park, Ralf Bundschuh, Matthew Schoffner, Nathan D. Jones, Jiaquan Liu, Jong-Bong Lee, Richard Fishel, Juana Martin-Lopez, Piotr Klajner
Publikováno v:
Journal of Biological Chemistry. 293:14285-14294
Sliding clamps on DNA consist of evolutionarily conserved enzymes that coordinate DNA replication, repair, and the cellular DNA damage response. MutS homolog (MSH) proteins initiate mismatch repair (MMR) by recognizing mispaired nucleotides and in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225a2fd53a5b7968c115fa31e6d180c5
https://doi.org/10.1074/jbc.ra118.002264
https://doi.org/10.1074/jbc.ra118.002264
Autor:
James A. London, Jiaquan Liu, Jeungphill Hanne, Brooke M. Britton, Jong-Bong Lee, Richard Fishel, Ryanggeun Lee, Keunsang Yang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
A shared paradigm of mismatch repair (MMR) across biology depicts extensive exonuclease-driven strand-specific excision that begins at a distant single-stranded DNA (ssDNA) break and proceeds back past the mismatched nucleotides. Historical reconstit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11c765fcf0a343259ea321d88d2eb10
https://doi.org/10.1038/s41467-019-13191-5
https://doi.org/10.1038/s41467-019-13191-5
Autor:
Jiaquan Liu, Jong-Bong Lee, Richard Fishel, Daehyung Kim, Jared Bennett, Jeungphill Hanne, Brooke M. Britton
Publikováno v:
Nature. 539:583-587
MutS and MutL—the highly conserved core proteins responsible for the repair of mismatched DNA—form sequential stable sliding clamps that together modulate one-dimensional diffusion along the DNA and, with MutH, facilitate the search for a distant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44ec770a4d380f40a27cde6cee3ca2f
https://doi.org/10.1038/nature20562
https://doi.org/10.1038/nature20562
Autor:
Jeungphill Hanne, Nathan D. Jones, Miguel Álvarez López, Jong-Bong Lee, Richard Fishel, Kristine E. Yoder, Mitchell B. Peake
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications
Nature Communications
Retroviruses must integrate their linear viral cDNA into the host genome for a productive infection. Integration is catalysed by the retrovirus-encoded integrase (IN), which forms a tetramer or octamer complex with the viral cDNA long terminal repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fdd92bf0b3ad1c4b5e1d666502ac3c
https://doaj.org/article/4c0178fb357c4b6c9e3c7ff0e81765af
https://doaj.org/article/4c0178fb357c4b6c9e3c7ff0e81765af
Autor:
James A. London, Jong-Bong Lee, Richard Fishel, Ryanggeun Lee, Brooke M. Britton, Jeungphill Hanne, Jiaquan Liu
Publikováno v:
Biophysical Journal. 116:73a-74a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0494a6e4d01c41a573b29a323acf18d
https://doi.org/10.1016/j.bpj.2018.11.439
https://doi.org/10.1016/j.bpj.2018.11.439
Publikováno v:
Nucleic Acids Research
Wrapping of genomic DNA into nucleosomes poses thermodynamic and kinetic barriers to biological processes such as replication, transcription, repair and recombination. Previous biochemical studies have demonstrated that in the presence of adenosine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9250d3a08eda8933687cbc57d39a8057
https://pubmed.ncbi.nlm.nih.gov/27738136
https://pubmed.ncbi.nlm.nih.gov/27738136
Autor:
Jong-Bong Lee, Richard Fishel, Jungsic Oh, Juana Martin-Lopez, Daehyung Kim, Ryanggeun Lee, Yongmoon Jeon, Jeungphill Hanne
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(12)
Mismatch repair (MMR) is activated by evolutionarily conserved MutS homologs (MSH) and MutL homologs (MLH/PMS). MSH recognizes mismatched nucleotides and form extremely stable sliding clamps that may be bound by MLH/PMS to ultimately authorize strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb761e56f7b9654ec7a8a8978a2efa0c
https://pubmed.ncbi.nlm.nih.gov/26951673
https://pubmed.ncbi.nlm.nih.gov/26951673