CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice.

Autor: Nieland L; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Vrijmoet AB; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA., Jetten IW; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA., Rufino-Ramos D; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA, 02115, USA., de Reus AJEM; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA., Breyne K; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA., Kleinstiver BP; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA, 02115, USA., Maguire CA; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02115, USA; Harvard Medical School, Boston, MA, 02116, USA., Broekman MLD; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands; Department of Neurosurgery, Haaglanden Medical Center, The Hague, 2512 VA, The Netherlands; Department of Neurosurgery, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Breakefield XO; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129,USA., Abels ER; Department of Neurosurgery, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands. Electronic address: e.r.abels@lumc.nl.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Nov 19. Date of Electronic Publication: 2024 Nov 19.

Responsiveness and minimal important change of seven PROMIS computerized adaptive tests (CAT) in patients with advanced chronic kidney disease.

Autor: Terwee CB; Department of Epidemiology and Data Science, Amsterdam UMC location Vrije Universiteit, P.O. box 7057, Amsterdam, 1007 MB, the Netherlands. cb.terwee@amsterdamumc.nl.; Amsterdam Public Health research institute, Methodology, Amsterdam, The Netherlands. cb.terwee@amsterdamumc.nl., van der Willik EM; Department of Epidemiology and Data Science, Amsterdam UMC location Vrije Universiteit, P.O. box 7057, Amsterdam, 1007 MB, the Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., van Breda F; Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., van Jaarsveld BC; Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., van de Putte M; Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Jetten IW; Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Dekker FW; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Meuleman Y; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., van Ittersum FJ; Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.

Publikováno v: Journal of patient-reported outcomes [J Patient Rep Outcomes] 2023 Apr 04; Vol. 7 (1), pp. 35. Date of Electronic Publication: 2023 Apr 04.