A Novel Microbial Culture Chamber Co-cultivation System to Study Algal-Bacteria Interactions Using Emiliania huxleyi and Phaeobacter inhibens as Model Organisms

Autor: Mariane S. Thøgersen, Jette Melchiorsen, Colin Ingham, Lone Gram

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Our understanding of microbial natural environments combines in situ experimentation with studies of specific interactions in laboratory-based setups. The purpose of this work was to develop, build and demonstrate the use of a microbial culture chamb

Externí odkaz: https://doaj.org/article/5c9ff6ffea174d2dad486c283ce201be

Global and Phylogenetic Distribution of Quorum Sensing Signals, Acyl Homoserine Lactones, in the Family of Vibrionaceae

Autor: Bastian Barker Rasmussen, Kristian Fog Nielsen, Henrique Machado, Jette Melchiorsen, Lone Gram, Eva C. Sonnenschein

Publikováno v: Marine Drugs, Vol 12, Iss 11, Pp 5527-5546 (2014)

Bacterial quorum sensing (QS) and the corresponding signals, acyl homoserine lactones (AHLs), were first described for a luminescent Vibrio species. Since then, detailed knowledge has been gained on the functional level of QS; however, the abundance

Externí odkaz: https://doaj.org/article/a8c6a5bf51164a29862699b7388d361a

An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria

Autor: Maria Maansson, Nikolaj G. Vynne, Andreas Klitgaard, Jane L. Nybo, Jette Melchiorsen, Don D. Nguyen, Laura M. Sanchez, Nadine Ziemert, Pieter C. Dorrestein, Mikael R. Andersen, Lone Gram

Publikováno v: mSystems, Vol 1, Iss 3 (2016)

ABSTRACT Microorganisms are a rich source of bioactives; however, chemical identification is a major bottleneck. Strategies that can prioritize the most prolific microbial strains and novel compounds are of great interest. Here, we present an integra

Externí odkaz: https://doaj.org/article/9906b1ac9e2b4d0ba8ac74b1086a3e87

Identification and Verification of the Prodigiosin Biosynthetic Gene Cluster (BGC) in Pseudoalteromonas rubra S4059

Autor: Thomas Isbrandt, Jette Melchiorsen, Emil Ørsted Christensen, Thomas Ostenfeld Larsen, Lone Gram, Sheng-Da Zhang, Xiyan Wang

Publikováno v: Microbiology Spectrum
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Wang, X, Isbrandt, T, Christensen, E Ø, Melchiorsen, J, Larsen, T O, Zhang, S-D & Gram, L 2021, ' Identification and Verification of the Prodigiosin Biosynthetic Gene Cluster (BGC) in Pseudoalteromonas rubra S4059 ', Microbiology Spectrum, vol. 9, no. 2, e01171-21 . https://doi.org/10.1128/Spectrum.01171-21

Pseudoalteromonas rubra S4059 produces the red pigment prodigiosin, which has pharmaceutical and industrial potential. Here, we targeted a putative prodigiosin-synthesizing transferase PigC, and a pigC in-frame deletion mutant did not produce prodigi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35aec6b14e7c32e0bd67a2ee6a5b0ccc
https://doi.org/10.1128/spectrum.01171-21

Changes in the microbiome of mariculture feed organisms after treatment with a potentially probiotic strain of Phaeobacter inhibens

Autor: Bastian Barker Rasmussen, Jette Melchiorsen, Eva C. Sonnenschein, Lone Gram, Karen Kiesbye Dittmann, Mikkel Bentzon-Tilia

Publikováno v: Dittmann, K K, Rasmussen, B B, Melchiorsen, J, Sonnenschein, E C, Gram, L & Bentzon-Tilia, M 2020, ' Changes in the microbiome of mariculture feed organisms after treatment with a potentially probiotic strain of Phaeobacter inhibens ', Applied and Environmental Microbiology, vol. 86, no. 14, e00499-20 . https://doi.org/10.1128/aem.00499-20
Appl Environ Microbiol

The Phaeobacter genus has been explored as probiotics in mariculture as a sustainable strategy for prevention of bacterial infections. Its antagonistic effect against common fish pathogens is predominantly due to the production of the antibacterial c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abbccf510c8ea692d0b8f06e9e90585
https://orbit.dtu.dk/en/publications/8de5028b-10e1-48a2-9416-7e8d818cd527