Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time.

Autor: Prakash P; Department of Chemistry, Purdue University West Lafayette IN 47907 USA gchopra@purdue.edu., Jethava KP; Department of Chemistry, Purdue University West Lafayette IN 47907 USA gchopra@purdue.edu., Korte N; Department of Neuroscience, Physiology and Pharmacology, University College London London WC1E 6BT UK., Izquierdo P; Department of Neuroscience, Physiology and Pharmacology, University College London London WC1E 6BT UK., Favuzzi E; Department of Neurobiology, Harvard Medical School 220 Longwood Avenue Boston MA 02115 USA.; Stanley Center at the Broad 75 Ames Street Cambridge MA 02142 USA., Rose IVL; Neuroscience Institute, NYU Grossman School of Medicine New York NY 10016 USA., Guttenplan KA; Department of Neurobiology, Stanford University Stanford CA 94305 USA., Manchanda P; Department of Chemistry, Purdue University West Lafayette IN 47907 USA gchopra@purdue.edu., Dutta S; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University West Lafayette IN 47907 USA., Rochet JC; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University West Lafayette IN 47907 USA.; Purdue Institute for Integrative Neuroscience, Purdue University West Lafayette IN 47907 USA., Fishell G; Department of Neurobiology, Harvard Medical School 220 Longwood Avenue Boston MA 02115 USA.; Stanley Center at the Broad 75 Ames Street Cambridge MA 02142 USA., Liddelow SA; Neuroscience Institute, NYU Grossman School of Medicine New York NY 10016 USA.; Department of Neuroscience & Physiology, NYU Grossman School of Medicine New York NY 10016 USA.; Department of Ophthalmology, NYU Grossman School of Medicine New York NY 10016 USA., Attwell D; Department of Neuroscience, Physiology and Pharmacology, University College London London WC1E 6BT UK., Chopra G; Department of Chemistry, Purdue University West Lafayette IN 47907 USA gchopra@purdue.edu.; Purdue Institute for Integrative Neuroscience, Purdue University West Lafayette IN 47907 USA.; Purdue Institute for Drug Discovery 720 Clinic Drive West Lafayette IN 47907 USA.; Purdue Center for Cancer Research, Purdue University West Lafayette IN 47907 USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University West Lafayette IN 47907 USA.

Publikováno v: Chemical science [Chem Sci] 2021 Jul 21; Vol. 12 (32), pp. 10901-10918. Date of Electronic Publication: 2021 Jul 21 (Print Publication: 2021).

Spectral deep learning for prediction and prospective validation of functional groups.

Autor: Fine JA; Department of Chemistry, Purdue University 560 Oval Drive West Lafayette IN 47907 USA gchopra@purdue.edu., Rajasekar AA; Department of Biological Engineering, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras Chennai 600036 India., Jethava KP; Department of Chemistry, Purdue University 560 Oval Drive West Lafayette IN 47907 USA gchopra@purdue.edu., Chopra G; Department of Chemistry, Purdue University 560 Oval Drive West Lafayette IN 47907 USA gchopra@purdue.edu.

Publikováno v: Chemical science [Chem Sci] 2020 Mar 13; Vol. 11 (18), pp. 4618-4630. Date of Electronic Publication: 2020 Mar 13.

Access to Imidazolidine-Fused Sulfamidates and Sulfamides Bearing a Quaternary Center via 1,3-Dipolar Cycloaddition of Nonstabilized Azomethine Ylides.

Autor: Laha JK; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062, India., Jethava KP; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2017 Apr 07; Vol. 82 (7), pp. 3597-3604. Date of Electronic Publication: 2017 Mar 27.

Intramolecular Acylation of Unactivated Pyridines or Arenes via Multiple C-H Functionalizations: Synthesis of All Four Azafluorenones and Fluorenones.

Autor: Laha JK; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research Sahibzada Ajit Singh Nagar, Punjab 160062, India., Jethava KP; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research Sahibzada Ajit Singh Nagar, Punjab 160062, India., Patel S; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research Sahibzada Ajit Singh Nagar, Punjab 160062, India., Patel KV; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research Sahibzada Ajit Singh Nagar, Punjab 160062, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2017 Jan 06; Vol. 82 (1), pp. 76-85. Date of Electronic Publication: 2016 Dec 14.

Scope of Successive C-H Functionalizations of the Methyl Group in 3-Picolines: Intramolecular Carbonylation of Arenes to the Metal-Free Synthesis of 4-Azafluorenones.

Autor: Laha JK; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062, India., Jethava KP; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062, India., Patel S; Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research , S. A. S. Nagar, Punjab 160062, India.

Publikováno v: Organic letters [Org Lett] 2015 Dec 04; Vol. 17 (23), pp. 5890-3. Date of Electronic Publication: 2015 Nov 20.