Výsledky vyhledávání - "Jesus S Distel"

Akademický článek

The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infection

Autor: Jenna C. McGuffey, Clay D. Jackson-Litteken, Gisela Di Venanzio, Aubree A. Zimmer, Jessica M. Lewis, Jesus S. Distel, Kyusik Q. Kim, Hani S. Zaher, Juan Alfonzo, Nichollas E. Scott, Mario F. Feldman

Publikováno v: mBio, Vol 14, Iss 5 (2023)

ABSTRACT Successful pathogens must be able to adapt to a multitude of stressors imposed by their host. Acinetobacter baumannii has emerged as a major global health threat due to its exceptional ability to adapt to hostile environments and skyrocketin

Externí odkaz: https://doaj.org/article/36fb02e91a4f408baf97b05f436e762d

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Akademický článek

Replicative Acinetobacter baumannii strains interfere with phagosomal maturation by modulating the vacuolar pH.

Autor: Jesus S Distel, Gisela Di Venanzio, Joseph J Mackel, David A Rosen, Mario F Feldman

Publikováno v: PLoS Pathogens, Vol 19, Iss 6, p e1011173 (2023)

Bacterial pneumonia is a common infection of the lower respiratory tract that can afflict patients of all ages. Multidrug-resistant strains of Acinetobacter baumannii are increasingly responsible for causing nosocomial pneumonias, thus posing an urge

Externí odkaz: https://doaj.org/article/e39c07c3212b4b70aab1c47b1b7b064a

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Akademický článek

Evolutionarily stable gene clusters shed light on the common grounds of pathogenicity in the Acinetobacter calcoaceticus-baumannii complex

Autor: Bardya Djahanschiri, Gisela Di Venanzio, Jesus S. Distel, Jennifer Breisch, Marius Alfred Dieckmann, Alexander Goesmann, Beate Averhoff, Stephan Göttig, Gottfried Wilharm, Mario F. Feldman, Ingo Ebersberger

Publikováno v: PLoS Genetics, Vol 18, Iss 6 (2022)

Nosocomial pathogens of the Acinetobacter calcoaceticus-baumannii (ACB) complex are a cautionary example for the world-wide spread of multi- and pan-drug resistant bacteria. Aiding the urgent demand for novel therapeutic targets, comparative genomics

Externí odkaz: https://doaj.org/article/116b5957598c440389508e076edc9432

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Akademický článek

InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis

Autor: Clay D. Jackson-Litteken, Gisela Di Venanzio, Nguyen-Hung Le, Nichollas E. Scott, Bardya Djahanschiri, Jesus S. Distel, Evan J. Pardue, Ingo Ebersberger, Mario F. Feldman

Publikováno v: mBio, Vol 13, Iss 3 (2022)

ABSTRACT Acinetobacter baumannii is an opportunistic pathogen of growing concern, as isolates are commonly multidrug resistant. While A. baumannii is most frequently associated with pulmonary infections, a significant proportion of clinical isolates

Externí odkaz: https://doaj.org/article/9d47591a74104d1796979b874d7b6fd9

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Akademický článek

Modern Acinetobacter baumannii clinical isolates replicate inside spacious vacuoles and egress from macrophages.

Autor: Gabriela Sycz, Gisela Di Venanzio, Jesus S Distel, Mariana G Sartorio, Nguyen-Hung Le, Nichollas E Scott, Wandy L Beatty, Mario F Feldman

Publikováno v: PLoS Pathogens, Vol 17, Iss 8, p e1009802 (2021)

Multidrug-resistant Acinetobacter baumannii infections are increasing at alarming rates. Therefore, novel antibiotic-sparing treatments to combat these A. baumannii infections are urgently needed. The development of these interventions would benefit

Externí odkaz: https://doaj.org/article/d09b4c9b97c44eaaab6d066fa2a98b86

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