Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jesus Murga-Moreno"'
Autor:
Irepan Salvador-Martínez, Jesus Murga-Moreno, Juan C. Nieto, Clara Alsinet, David Enard, Holger Heyn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human immune cells are under constant evolutionary pressure, primarily through their role as first line of defence against pathogens. Most studies on immune adaptation are, however, based on protein-coding genes without considering their cel
Externí odkaz:
https://doaj.org/article/a5ee579328c6429ea1cc1477e98c2c7b
Publikováno v:
eLife, Vol 10 (2021)
Advances in genome sequencing have improved our understanding of the genetic basis of human diseases, and thousands of human genes have been associated with different diseases. Recent genomic adaptation at disease genes has not been well characterize
Externí odkaz:
https://doaj.org/article/5db49e16e08f432382eef960a9a04d08
Pathogens were a major driver of genetic adaptation during human evolution. Viruses in particular were a dominant driver of adaptation in the thousands of proteins that physically interact with viruses (VIPs for Virus-Interacting Proteins). This howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77cabd35fb55b3e1b576d0bd6de9ccd4
https://doi.org/10.1101/2022.12.01.518739
https://doi.org/10.1101/2022.12.01.518739
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Advances in genome sequencing have improved our understanding of the genetic basis of human diseases, and thousands of human genes have been associated with different diseases. Recent genomic adaptation at disease genes has not been well characterize