Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Jesus Gonzalez-Bosquet"'
Autor:
Garima Dixit, Jesus Gonzalez‐Bosquet, Joseph Skurski, Eric J. Devor, Erin B. Dickerson, Warren B. Nothnick, Priya D. Issuree, Kimberly K. Leslie, Thorsten Maretzky
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Mutations in the receptor tyrosine kinase gene fibroblast growth factor receptor 2 (FGFR2) occur at a high frequency in endometrial cancer (EC) and have been linked to advanced and recurrent disease. However, little is known about
Externí odkaz:
https://doaj.org/article/e1ddfbedbc6649e691ed24abee9aaa3f
Autor:
Jesus Gonzalez-Bosquet, S. John Weroha, Jamie N. Bakkum-Gamez, Amy L. Weaver, Michaela E. McGree, Sean C. Dowdy, Abimbola O. Famuyide, Benjamin R. Kipp, Kevin C. Halling, Siddhartha Yadav, Fergus J. Couch, Karl C. Podratz
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveTo identify high-risk disease in clinicopathologic low-risk endometrial cancer (EC) with high microsatellite instability (MSI-H) or no specific molecular profile (NSMP) and therapeutic insensitivity in clinicopathologic high-risk MSI-H/NSMP
Externí odkaz:
https://doaj.org/article/32b034603ff54448b98bb03612a864b7
Autor:
Jesus Gonzalez-Bosquet, S John Weroha, Jamie N Bakkum-Gamez, Amy L Weaver, Michaela E McGree, Sean C Dowdy, Abimbola O Famuyide, Benjamin R Kipp, Kevin C Halling, Siddhartha Yadav, Fergus J Couch, Karl C Podratz
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278408 (2022)
In endometrial cancer, occult high-risk subtypes (rooted in histomorphologically low-risk disease) with insensitivity to adjuvant therapies impede improvements in therapeutic efficacy. Therefore, we aimed to assess the ability of molecular high-risk
Externí odkaz:
https://doaj.org/article/70ac29b94c314af7a0ea660185f64472
Autor:
Eric J. Devor, Brandon M. Schickling, Jace R. Lapierre, David P. Bender, Jesus Gonzalez-Bosquet, Kimberly K. Leslie
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 942 (2021)
Elevated expression of placenta-specific protein 1 (PLAC1) is associated with the increased proliferation and invasiveness of a variety of human cancers, including ovarian cancer. Recent studies have shown that the tumor suppressor p53 directly suppr
Externí odkaz:
https://doaj.org/article/5e27e07441e14791ae4d52403dc2c939
Autor:
Jesus Gonzalez-Bosquet, Jacob Calcei, Jun S Wei, Montserrat Garcia-Closas, Mark E Sherman, Stephen Hewitt, Joseph Vockley, Jolanta Lissowska, Hannah P Yang, Javed Khan, Stephen Chanock
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14522 (2011)
Identification of somatic mutations in cancer is a major goal for understanding and monitoring the events related to cancer initiation and progression. High resolution melting (HRM) curve analysis represents a fast, post-PCR high-throughput method fo
Externí odkaz:
https://doaj.org/article/0b219cc392fb496f992a46ca70e857cd
Autor:
Devor, Jesus Gonzalez-Bosquet, Megan E. McDonald, David P. Bender, Brian J. Smith, Kimberly K. Leslie, Michael J. Goodheart, Eric J.
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3316
There are strong correlations between the microbiome and human disease, including cancer. However, very little is known about potential mechanisms associated with malignant transformation in microbiome-associated gynecological cancer, except for HPV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a56ca148822d490beb2655086d8b54a4
Autor:
Nicholas Cardillo, Eric Devor, Christian Calma, Silvana Pedra Nobre, Sofia Gabrilovich, David P. Bender, Michael Goodheart, Jesus Gonzalez‐Bosquet
Publikováno v:
Acta Obstetricia et Gynecologica Scandinavica. 101:1085-1092
The survival benefits of surgical cytoreduction in ovarian cancer are well-established. However, the surgical outcome has never been assessed while controlling for the efficacy of chemotherapy. This leaves the possibility that cytoreduction may not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418bca7d346499fe3bdfeb76522a530b
https://doi.org/10.1111/aogs.14415
https://doi.org/10.1111/aogs.14415
Autor:
Ellen L. Goode, Stacey J. Winham, David D. Bowtell, Jesus Gonzalez Bosquet, Tanja Pejovic, Martin Widschwendter, Michael S. Anglesio, Dinuka Ariyaratne, Jennifer A. Doherty, Sian Fereday, Dale W. Garsed, Brooke D. Jorgensen, Martin Köbel, Nadja Pejovic, Susan J. Ramus, Aline Talhouk, Nadia Traficante, Robert A. Vierkant, Sebastian M. Armasu, Bryan M. McCauley, Mark E. Sherman, Julie M. Cunningham, Matthew S. Block, Chen Wang
Supplementary Figure 4: Correlations between Methylation at CpG Sites and TAP1 mRNA Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2430ad7223d7ccda62b7ebdea698ae9b
https://doi.org/10.1158/1055-9965.22494867
https://doi.org/10.1158/1055-9965.22494867
Autor:
Ellen L. Goode, Stacey J. Winham, David D. Bowtell, Jesus Gonzalez Bosquet, Tanja Pejovic, Martin Widschwendter, Michael S. Anglesio, Dinuka Ariyaratne, Jennifer A. Doherty, Sian Fereday, Dale W. Garsed, Brooke D. Jorgensen, Martin Köbel, Nadja Pejovic, Susan J. Ramus, Aline Talhouk, Nadia Traficante, Robert A. Vierkant, Sebastian M. Armasu, Bryan M. McCauley, Mark E. Sherman, Julie M. Cunningham, Matthew S. Block, Chen Wang
Supplementary Figure 1: Methylation Signature Approximation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142de5e90288c112b042e3e035d61f7f
https://doi.org/10.1158/1055-9965.22494876.v1
https://doi.org/10.1158/1055-9965.22494876.v1
Autor:
Ellen L. Goode, Stacey J. Winham, David D. Bowtell, Jesus Gonzalez Bosquet, Tanja Pejovic, Martin Widschwendter, Michael S. Anglesio, Dinuka Ariyaratne, Jennifer A. Doherty, Sian Fereday, Dale W. Garsed, Brooke D. Jorgensen, Martin Köbel, Nadja Pejovic, Susan J. Ramus, Aline Talhouk, Nadia Traficante, Robert A. Vierkant, Sebastian M. Armasu, Bryan M. McCauley, Mark E. Sherman, Julie M. Cunningham, Matthew S. Block, Chen Wang
Supplementary Figure 2: No Association between Methylation Signature and Baseline Clinical Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f33c8cdcacf6e49ac2767d68a078968
https://doi.org/10.1158/1055-9965.22494873
https://doi.org/10.1158/1055-9965.22494873