Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Jesus Garcia-Foncillas"'
Autor:
Javier Martin-Broto, Jeronimo Martinez-Garcia, David S. Moura, Andres Redondo, Antonio Gutierrez, Antonio Lopez-Pousa, Javier Martinez-Trufero, Isabel Sevilla, Roberto Diaz-Beveridge, Maria Pilar Solis-Hernandez, Amancio Carnero, Marco Perez, David Marcilla, Jesus Garcia-Foncillas, Pablo Romero, Javier Fernandez-Jara, Daniel Lopez-Lopez, Ivan Arribas, Nadia Hindi
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors demonstrated activity in terms of progression-free survival (PFS) in advanced dedifferentiated liposarcoma (DD-LPS), a sarcoma with CDK4 amplification. CDK4 overexpression is by far more c
Externí odkaz:
https://doaj.org/article/0c66d90901d244e6922dd1f9ea0a3f1f
Autor:
Carlos Lacalle-Gonzalez, Maria Florez-Cespedes, Lara Sanz-Criado, Michael Ochieng’ Otieno, Edurne Ramos-Muñoz, Maria Jesus Fernandez-Aceñero, Luis Ortega-Medina, Jesus Garcia-Foncillas, Javier Martinez-Useros
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2812 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive neoplasm with very poor patient survival outcomes despite available treatments. There is an urgent need for new potential treatment options and novel biomarkers for these patients. Delta-like c
Externí odkaz:
https://doaj.org/article/2d55f38ea8944f848534712b13302ea6
Autor:
Abdul Rahman Jazieh, Stephen L. Chan, Giuseppe Curigliano, Natalie Dickson, Vanessa Eaton, Jesus Garcia-Foncillas, Terry Gilmore, Leora Horn, David J. Kerr, Jeeyun Lee, Clarissa Mathias, Angélica Nogueira-Rodrigues, Lori Pierce, Alvaro Rogado, Richard L. Schilsky, Jean-Charles Soria, Olivier Vandenberg, Jeremy L. Warner, Kazuhiro Yoshida
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1461-1471 (2020)
PURPOSEIn response to the COVID-19 pandemic, the ASCO launched a Global Webinar Series to address various aspects of cancer care during the pandemic. Here we present the lessons learned and recommendations that have emerged from these webinars.METHOD
Externí odkaz:
https://doaj.org/article/0d27d774c66442c0a460bd5b747a5dfd
Autor:
Kamal S. Saini, Begoña de las Heras, Ruth Plummer, Victor Moreno, Marco Romano, Javier de Castro, Philippe Aftimos, Judy Fredriksson, Gouri Shankar Bhattacharyya, Martin Sebastian Olivo, Gaia Schiavon, Kevin Punie, Jesus Garcia-Foncillas, Ernesto Rogata, Richie Pfeiffer, Cecilia Orbegoso, Kenneth Morrison, Giuseppe Curigliano, Lynda Chin, Monika Lamba Saini, Øystein Rekdal, Steven Anderson, Javier Cortes, Manuela Leone, Janet Dancey, Chris Twelves, Ahmad Awada
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1357-1362 (2020)
Externí odkaz:
https://doaj.org/article/e753a4f9fda043498869674261249653
Autor:
Laura Del Puerto‐Nevado, Aranzazu Santiago‐Hernandez, Sonia Solanes‐Casado, Nieves Gonzalez, Marta Ricote, Marta Corton, Isabel Prieto, Sebastian Mas, Ana Belen Sanz, Oscar Aguilera, Carmen Gomez‐Guerrero, Carmen Ayuso, Alberto Ortiz, Federico Rojo, Jesus Egido, Jesus Garcia‐Foncillas, Pablo Minguez, Gloria Alvarez‐Llamas, on behalf of the DiabetesCancerConnect Consortium
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1887-1897 (2019)
Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of cancer, including colon cancer (CC). However, we recently reported no influence of T2DM on CC prognosis, suggesting that any effect might be at the early stages of tumor de
Externí odkaz:
https://doaj.org/article/2d414700dbd5494194adaa5a938914cc
Autor:
Laura Del Puerto‐Nevado, Pablo Minguez, Marta Corton, Sonia Solanes‐Casado, Isabel Prieto, Sebastian Mas, Ana Belen Sanz, Paula Gonzalez‐Alonso, Cristina Villaverde, Sergio Portal‐Nuñez, Oscar Aguilera, Carmen Gomez‐Guerrero, Pedro Esbrit, Fernando Vivanco, Nieves Gonzalez, Carmen Ayuso, Alberto Ortiz, Federico Rojo, Jesus Egido, Gloria Alvarez‐Llamas, Jesus Garcia‐Foncillas, the DiabetesCancerConnect Consortium
Publikováno v:
Molecular Oncology, Vol 13, Iss 4, Pp 857-872 (2019)
The potential involvement of type 2 diabetes mellitus (T2DM) as a risk factor for colon cancer (CC) has been previously reported. While several clinical studies show a higher incidence of CC and a lower survival rate in diabetics, others report no as
Externí odkaz:
https://doaj.org/article/dcc57d50d777408bb199fbd0ef72fef9
Autor:
Mariangela De Robertis, Tommaso Mazza, Caterina Fusilli, Luisa Loiacono, Maria Luana Poeta, Massimo Sanchez, Emanuela Massi, Giuseppe Lamorte, Maria Grazia Diodoro, Edoardo Pescarmona, Emanuela Signori, Graziano Pesole, Angelo Luigi Vescovi, Jesus Garcia-Foncillas, Vito Michele Fazio
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract EphB2 and EphA2 control stemness and differentiation in the intestinal mucosa, but the way they cooperate with the complex mechanisms underlying tumor heterogeneity and how they affect the therapeutic outcome in colorectal cancer (CRC) patie
Externí odkaz:
https://doaj.org/article/a4894f09e2574323b31d8cfe65188d20
Autor:
Nuria Garcia-Carbonero, Javier Martinez-Useros, Weiyao Li, Alberto Orta, Nuria Perez, Cristina Carames, Tatiana Hernandez, Irene Moreno, Gloria Serrano, Jesus Garcia-Foncillas
Publikováno v:
Cells, Vol 9, Iss 1, p 219 (2020)
KRAS mutation is a confirmed predictive biomarker for anti-EGFR monoclonal antibody therapy response for metastatic colorectal cancer. However, its prognosis impact and the predictive potential for first-line standard chemotherapy remains unclear. On
Externí odkaz:
https://doaj.org/article/e80b937bee9349aab15afafbd3a2ce62
Autor:
Javier Martinez-Useros, Tihomir Georgiev-Hristov, María Jesús Fernández-Aceñero, Aurea Borrero-Palacios, Alberto Indacochea, Santiago Guerrero, Weiyao Li, Arancha Cebrián, Teresa Gómez Del Pulgar, Alberto Puime-Otin, Laura Del Puerto-Nevado, María Rodríguez-Remírez, Nuria Pérez, Angel Celdrán, Fátima Gebauer, Jesus Garcia-Foncillas
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182044 (2017)
Pancreatic ductal adenocarcinoma is an aggressive form of pancreatic cancer and the fourth leading cause of cancer-related death. When possible, curative approaches are based on surgical resection, though not every patient is a candidate for surgery.
Externí odkaz:
https://doaj.org/article/a43684020cda4a85af2f6732dc23d0f1
Autor:
Isabel Prieto, Laura Del Puerto-Nevado, Nieves Gonzalez, Sergio Portal-Nuñez, Sandra Zazo, Marta Corton, Pablo Minguez, Carmen Gomez-Guerrero, Jose Miguel Arce, Ana Belen Sanz, Sebastian Mas, Oscar Aguilera, Gloria Alvarez-Llamas, Pedro Esbrit, Alberto Ortiz, Carmen Ayuso, Jesus Egido, Federico Rojo, Jesus Garcia-Foncillas, DiabetesCancerConnect Consortium
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172300 (2017)
BACKGROUND:Multiple observational studies suggest an increased risk of colon cancer in patients with diabetes mellitus (DM). This can theoretically be the result of an influence of the diabetic environment on carcinogenesis or the tumor biologic beha
Externí odkaz:
https://doaj.org/article/093b7915bf0f48549b17b68362a443a7