Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jesus Fernandez-Rodriguez"'
Autor:
Miryoung Song, David J. Sukovich, Luciano Ciccarelli, Julia Mayr, Jesus Fernandez-Rodriguez, Ethan A. Mirsky, Alex C. Tucker, D. Benjamin Gordon, Thomas C. Marlovits, Christopher A. Voigt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The type III secretion system is a needle-like molecular machine under tight regulatory control. Here the authors construct a synthetic type III secretion system gene cluster by deconstructing and rebuilding the wild-typeSalmonellapathogenicity islan
Externí odkaz:
https://doaj.org/article/0b09031c9865442aa10942c864607414
Autor:
Andreas K Brödel, Loïc Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Marion Arraou, Gautier Prevot, Dalila Spadoni, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
Microbiome research is revealing a growing number of bacterial genes that impact our health. While CRISPR-derived tools have shown great success in editing disease-driving genes in human cells, we currently lack the tools to achieve comparable succes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94baaccca1ab1facb8b75166ad2568ca
https://doi.org/10.1101/2022.09.30.509847
https://doi.org/10.1101/2022.09.30.509847
Akademický článek
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Publikováno v:
Oxford University Press
Nucleic Acids Research
Nucleic Acids Research
Genetic engineering projects often require control over when a protein is degraded. To this end, we use a fusion between a degron and an inactivating peptide that can be added to the N-terminus of a protein. When the corresponding protease is express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165982ecb0224b2bc291a9f6dfb455a3
https://doi.org/10.1093/nar/gkw537
https://doi.org/10.1093/nar/gkw537
Publikováno v:
Nature Chemical Biology. 13:706-708
A synthetic biology system composed of light-wavelength-responsive genetic regulators, signal-processing circuits and pigment-production pathways have resulted in an Escherichia coli strain that can record color images in RGB format. Optogenetic tool
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa6030b82adf0c3a68e10cbcfb2c300
https://doi.org/10.1038/nchembio.2390
https://doi.org/10.1038/nchembio.2390
Akademický článek
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Autor:
Jesus Fernandez-Rodriguez, D. Benjamin Gordon, Lei Yang, Thomas E. Gorochowski, Christopher A. Voigt
Publikováno v:
ACS Synthetic Biology. 4:1361-1372
Genetic memory can be implemented using enzymes that catalyze DNA inversions, where each orientation corresponds to a "bit". Here, we use two DNA invertases (FimE and HbiF) that reorient DNA irreversibly between two states with opposite directionalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fbbe178f68efb61c1676b3211bfef5
https://doi.org/10.1021/acssynbio.5b00170
https://doi.org/10.1021/acssynbio.5b00170
Autor:
Conor J McClune, Alec A. K. Nielsen, Timothy K. Lu, Jesus Fernandez-Rodriguez, Michael T. Laub, Lei Yang, Christopher A. Voigt
Publikováno v:
Nature methods
PMC
PMC
Genetic memory enables the recording of information in the DNA of living cells. Memory can record a transient environmental signal or cell state that is then recalled at a later time. Permanent memory is implemented using irreversible recombinases th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970f0819405271493a8ae0486562be6c
https://doi.org/10.1038/nmeth.3147
https://doi.org/10.1038/nmeth.3147
Autor:
Thomas C. Marlovits, Alex C. Tucker, Christopher A. Voigt, Luciano Ciccarelli, Jesus Fernandez-Rodriguez, Mi Ryoung Song, Julia Mayr, Ethan A Mirsky, David J. Sukovich, D. Benjamin Gordon
Publikováno v:
Nature Communications
Nature Communications 8, 14737 (2017). doi:10.1038/ncomms14737
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications 8, 14737 (2017). doi:10.1038/ncomms14737
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications 8, 14737 (2017). doi:10.1038/ncomms14737
Gram-negative bacteria secrete proteins using a type III secretion system (T3SS), which functions as a needle-like molecular machine. The many proteins involved in T3SS construction
Gram-negative bacteria secrete proteins using a type III secretion system (T3SS), which functions as a needle-like molecular machine. The many proteins involved in T3SS construction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3f9d300200a910fa524a94e9005b09
https://pubmed.ncbi.nlm.nih.gov/28485369
https://pubmed.ncbi.nlm.nih.gov/28485369
Publikováno v:
Protein Science. 21:511-519
A synthetic de novo designed heterodimeric coiled-coil was used to copurify two target fluorescent proteins, Venus and enhanced cyan fluorescent protein (ECFP). The coiled-coil consists of two 21-amino acid repetitive sequences, (EIAALEK)3 and (KIAAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ee860f13cbc94432170b09bc384d4b1
https://doi.org/10.1002/pro.2035
https://doi.org/10.1002/pro.2035