Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Jesus F. San Miguel"'
Autor:
Daniel Alameda, Borja Saez, David Lara-Astiaso, Sarai Sarvide, Marta Lasa, Diego Alignani, Idoia Rodriguez, Sonia Garate, Amaia Vilas, Bruno Paiva, Matias Alfonso-Olmos, Jose Maria Lamo de Espinosa, Felipe Prosper, Jesus F. San Miguel, Patricia Maiso
Publikováno v:
Haematologica, Vol 105, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/229b3097755843fb95fdd43460522b44
Autor:
Philippe Moreau, Pieter Sonneveld, Mario Boccadoro, Gordon Cook, Ma Victoria Mateos, Hareth Nahi, Hartmut Goldschmidt, Meletios A. Dimopoulos, Paulo Lucio, Joan Bladé, Michel Delforge, Roman Hajek, Heinz Ludwig, Thierry Facon, Jesus F. San Miguel, Hermann Einsele
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Adoptive cellular therapy using chimeric antigen receptor T-cell (CART) therapy is currently being evaluated in patients with relapsed / refractory multiple myeloma (MM). The majority of CAR-T cell programs now being tested in clinical trials are tar
Externí odkaz:
https://doaj.org/article/832959da49bd439dbd6340d7e347a6f4
Autor:
Yuji Mishima, Bruno Paiva, Jiantao Shi, Jihye Park, Salomon Manier, Satoshi Takagi, Mira Massoud, Adriana Perilla-Glen, Yosra Aljawai, Daisy Huynh, Aldo M. Roccaro, Antonio Sacco, Marzia Capelletti, Alexandre Detappe, Diego Alignani, Kenneth C. Anderson, Nikhil C. Munshi, Felipe Prosper, Jens G. Lohr, Gavin Ha, Samuel S. Freeman, Eliezer M. Van Allen, Viktor A. Adalsteinsson, Franziska Michor, Jesus F. San Miguel, Irene M. Ghobrial
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 218-224 (2017)
The development of sensitive and non-invasive “liquid biopsies” presents new opportunities for longitudinal monitoring of tumor dissemination and clonal evolution. The number of circulating tumor cells (CTCs) is prognostic in multiple myeloma (MM
Externí odkaz:
https://doaj.org/article/0ab1ac700cc547768b8dbcbc3419651a
Autor:
Jesus F. San Miguel, Katja C. Weisel, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Philippe Moreau, Anne Banos, Albert Oriol, Laurent Garderet, Michele Cavo, Valentina Ivanova, Adrian Alegre, Joaquin Martinez-Lopez, Christine Chen, Christoph Renner, Nizar Jacques Bahlis, Xin Yu, Terri Teasdale, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Meletios A. Dimopoulos
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Pomalidomide is a distinct oral IMiD® immunomodulatory agent with direct antimyeloma, stromal-support inhibitory, and immunomodulatory effects. The pivotal, multicenter, open-label, randomized phase 3 trial MM-003 compared pomalidomide + low-dose de
Externí odkaz:
https://doaj.org/article/01073b8b38a44d4986806589d588c09e
Autor:
Meletios A. Dimopoulos, Katja C. Weisel, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Philippe Moreau, Anne Banos, Albert Oriol, Laurent Garderet, Michele Cavo, Valentina Ivanova, Adrian Alegre, Joaquin Martinez-Lopez, Christine Chen, Andrew Spencer, Stefan Knop, Nizar J. Bahlis, Christoph Renner, Xin Yu, Kevin Hong, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Jesus F. San Miguel
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Patients with refractory or relapsed and refractory multiple myeloma who no longer receive benefit from novel agents have limited treatment options and short expected survival. del(17p) and t(4;14) are correlated with shortened survival. The phase 3
Externí odkaz:
https://doaj.org/article/098a6e1ecfe649c8ae8d56fc2fba2b0d
Autor:
Leandro S. Thiago, Martin Perez-Andres, Ana Balanzategui, Maria E. Sarasquete, Bruno Paiva, Maria Jara-Acevedo, Paloma Barcena, Maria Luz Sanchez, Julia Almeida, Marcos González, Jesus F. San Miguel, Ramón Garcia-Sanz, Alberto Orfao
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
The B-cell compartment in which multiple myeloma stem cells reside remains unclear. We investigated the potential presence of mature, surface-membrane immunoglobulin-positive B lymphocytes clonally related to the tumor bone marrow plasma cells among
Externí odkaz:
https://doaj.org/article/14461ed445cc49e3a21307249a590010
Autor:
Martin Schmidt-Hieber, María Laura Gutiérrez, Martin Pérez-Andrés, Bruno Paiva, Ana Rasillo, Maria Dolores Tabernero, José Maria Sayagués, Antonio Lopez, Paloma Bárcena, María Luz Sanchez, Norma C. Gutiérrez, Jesus F. San Miguel, Alberto Orfao
Publikováno v:
Haematologica, Vol 98, Iss 2 (2013)
Cytogenetic studies in clonal plasma cell disorders have mainly been done in whole bone marrow or CD138+ microbead-enriched plasma cells and suggest that recurrent immunoglobulin heavy chain translocations - e.g. t(4;14) -are primary oncogenetic even
Externí odkaz:
https://doaj.org/article/0ba42a880fec4aba92cd618d6cea3d6b
Autor:
Martin Schmidt-Hieber, Martin Pérez-Andrés, Bruno Paiva, Juan Flores-Montero, Jose J. Perez, Norma C. Gutierrez, Maria-Belen Vidriales, Sergio Matarraz, Jesus F. San Miguel, Alberto Orfao
Publikováno v:
Haematologica, Vol 96, Iss 2 (2011)
Aberrant CD117 expression is associated with a favorable outcome in multiple myeloma. We analyzed 106 patients with symptomatic multiple myeloma (n=50), smoldering multiple myeloma (n=38) and monoclonal gammopathy of undetermined significance (n=18)
Externí odkaz:
https://doaj.org/article/a2754ca7f9724d65a6d82ee3de08c9f6
Autor:
Gareth J. Morgan, Kenneth C. Anderson, Luciano J. Costa, Shaji K. Kumar, Brian A. Walker, Ajai Chari, Wee Joo Chng, Joseph Caers, Francesca Gay, C. Ola Landgren, Robert Z. Orlowski, Irene M. Ghobrial, Kathryn E. Morgan, Joseph R. Mikhael, Jonathan J. Keats, Katja Weisel, Martin F. Kaiser, P. Leif Bergsagel, A. Keith Stewart, Pieter Sonneveld, Sagar Lonial, Hearn Jay Cho, Daniel Auclair, Jill Corre, Eileen M. Boyle, Hermann Einsele, Jesus F. San-Miguel, Saad Z. Usmani, Charlotte Pawlyn, Faith E. Davies
Summary:The multiple myeloma treatment landscape has changed dramatically. This change, paralleled by an increase in scientific knowledge, has resulted in significant improvement in survival. However, heterogeneity remains in clinical outcomes, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c920d3765217b272b505dec803305de
https://doi.org/10.1158/2643-3230.c.6550602
https://doi.org/10.1158/2643-3230.c.6550602
Autor:
Gareth J. Morgan, Kenneth C. Anderson, Luciano J. Costa, Shaji K. Kumar, Brian A. Walker, Ajai Chari, Wee Joo Chng, Joseph Caers, Francesca Gay, C. Ola Landgren, Robert Z. Orlowski, Irene M. Ghobrial, Kathryn E. Morgan, Joseph R. Mikhael, Jonathan J. Keats, Katja Weisel, Martin F. Kaiser, P. Leif Bergsagel, A. Keith Stewart, Pieter Sonneveld, Sagar Lonial, Hearn Jay Cho, Daniel Auclair, Jill Corre, Eileen M. Boyle, Hermann Einsele, Jesus F. San-Miguel, Saad Z. Usmani, Charlotte Pawlyn, Faith E. Davies
Supplementary Table from Perspectives on the Risk-Stratified Treatment of Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7816f1718b19577dc748c86149b76a15
https://doi.org/10.1158/2643-3230.22544313.v1
https://doi.org/10.1158/2643-3230.22544313.v1