Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jesus F. Acevedo"'
Autor:
Meadow M Good, T Ignacio Montoya, Haolin Shi, Jun Zhou, YiHui Huang, Liping Tang, Jesus F Acevedo, R Ann Word
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186268 (2017)
The pathophysiology and natural history of pelvic organ prolapse (POP) are poorly understood. Consequently, our approaches to treatment of POP are limited. Alterations in the extracellular matrix components of pelvic support ligaments and vaginal tis
Externí odkaz:
https://doaj.org/article/3e8aea7098bf43e3966f20652a0e6851
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Vaginal delivery with obstetrical trauma is a risk factor for pelvic organ prolapse later in life. Loss of fibulin-5 (FBLN5), an elastogenesis-promoting cellular matrix protein, results in prolapse in mice. Here, we evaluated effects of pregnancy, pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f90eae4079eb8b4a8de4857ab48b080
http://link.springer.com/article/10.1038/s41598-020-63031-6
http://link.springer.com/article/10.1038/s41598-020-63031-6
Autor:
Neha G. Gaddam, Maria E. Florian-Rodriguez, Jesus F. Acevedo, Adam M. Hare, R. Ann Word, Haolin Shi
Publikováno v:
Tissuecell. 73
Objective Cellular senescence, associated with aging, leads to impaired tissue regeneration. We hypothesize that vaginal injury initiates cell senescence, further propagated during aging resulting in pelvic organ prolapse (POP). Our objective was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ce5860afefa509f4c27a61e2e424cc
https://pubmed.ncbi.nlm.nih.gov/34560406
https://pubmed.ncbi.nlm.nih.gov/34560406
Autor:
Andrew T. Moehlman, David Prokai, Jaideep Chaudhary, Ashutosh Pudasaini, Alexandrea E. Waits, Patrick W. Keller, Mohammed Kanchwala, F. Kent Hamra, Karen M. Chapman, Jesus F. Acevedo, Bruce R. Carr, Xing Chao
Publikováno v:
iScience
iScience, Vol 24, Iss 1, Pp 101880-(2021)
iScience, Vol 24, Iss 1, Pp 101880-(2021)
Summary In adult males, spermatogonia maintain lifelong spermatozoa production for oocyte fertilization. To understand spermatogonial metabolism we compared gene profiles in rat spermatogonia to publicly available mouse, monkey, and human spermatogon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5088fed42a11182e6e0b7c0c59ef568
http://europepmc.org/articles/PMC7797946
http://europepmc.org/articles/PMC7797946
Autor:
Oscar Flores-Herrera, Néstor F. Díaz, Anayansi Molina-Hernández, Asyadette Barrera‐García, Edgar Barrientos‐Galeana, Héctor Flores-Herrera, Mauricio Osorio-Caballero, María C. Álvarez‐Cabrera, Jesus F. Acevedo, Guadalupe García-López
Publikováno v:
Journal of Cellular and Molecular Medicine
The extracellular heat shock proteins (eHsp) family act as molecular chaperones regulating folding, transporting protein and are associated with immune modulation in different physiological and pathological processes. They have been localized in diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cead721b4e6a507a24d113e3344f2a
https://doi.org/10.1111/jcmm.13824
https://doi.org/10.1111/jcmm.13824
Autor:
Pedro Antonio Maldonado, R.A. Word, Patrick W. Keller, Christopher M. Ripperda, John M. Shelton, Jesus F. Acevedo, Yucel Akgul
Publikováno v:
Menopause (New York, N.y.)
Supplemental Digital Content is available in the text
Objective: Reconstructive surgery for pelvic organ prolapse is plagued with high failure rates possibly due to impaired healing or regeneration of the vaginal wall. Here, we tested the hypoth
Objective: Reconstructive surgery for pelvic organ prolapse is plagued with high failure rates possibly due to impaired healing or regeneration of the vaginal wall. Here, we tested the hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b18678b4028c6bdfc05c10ef09cc4fb
http://europepmc.org/articles/PMC5484719
http://europepmc.org/articles/PMC5484719
Publikováno v:
Biology of Reproduction. 96:81-92
Although the positive effects of vaginal estrogens and the selective estrogen receptor modulator, ospemifene (OS), on the vaginal epithelium are well recognized, less is known regarding the effects of these therapies on the lower urinary tract or vag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bd70e7d9e1ec45d370bd7c2b0f1ce1
https://doi.org/10.1095/biolreprod.116.144428
https://doi.org/10.1095/biolreprod.116.144428
Autor:
Liping Tang, Yihui Huang, T. Ignacio Montoya, Haolin Shi, Jesus F. Acevedo, Jun Zhou, Meadow M. Good, R. Ann Word
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186268 (2017)
PLoS ONE
PLoS ONE
The pathophysiology and natural history of pelvic organ prolapse (POP) are poorly understood. Consequently, our approaches to treatment of POP are limited. Alterations in the extracellular matrix components of pelvic support ligaments and vaginal tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c686d3ab50fbfdaef32a938da9f81829
http://europepmc.org/articles/PMC5657977?pdf=render
http://europepmc.org/articles/PMC5657977?pdf=render
Publikováno v:
Obstetrics & Gynecology. 115:815-823
OBJECTIVE: To estimate the effect of myogenic stem cells on contractile function of the external anal sphincter after transection with or without repair in an animal model. METHODS: One hundred twenty virginal female rats were randomly assinged to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8f555288eb435833ff1a7c3202f378
https://doi.org/10.1097/aog.0b013e3181d56cc5
https://doi.org/10.1097/aog.0b013e3181d56cc5
Autor:
Jesus F. Acevedo, Lihua Y. Marmorstein, Patrick W. Keller, Elaine C. Davis, David D. Rahn, R. Ann Word, Shayzreen M. Roshanravan
Publikováno v:
The American Journal of Pathology. 174:206-215
Fibulin-5 is crucial for normal elastic fiber synthesis in the vaginal wall; more than 90% of fibulin-5-knockout mice develop pelvic organ prolapse by 20 weeks of age. In contrast, fibulin-1 and -2 deficiencies do not result in similar pathologies, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc6c2e3e74b14b43e5f1da838cef0a5
https://doi.org/10.2353/ajpath.2009.080212
https://doi.org/10.2353/ajpath.2009.080212