Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jesus Borrego"'
Autor:
Muhammad Umair Naseem, Georgina Gurrola-Briones, Margarita R. Romero-Imbachi, Jesus Borrego, Edson Carcamo-Noriega, José Beltrán-Vidal, Fernando Z. Zamudio, Kashmala Shakeel, Lourival Domingos Possani, Gyorgy Panyi
Publikováno v:
Toxins, Vol 15, Iss 1, p 41 (2023)
A novel peptide, Cm39, was identified in the venom of the scorpion Centruroides margaritatus. Its primary structure was determined. It consists of 37 amino acid residues with a MW of 3980.2 Da. The full chemical synthesis and proper folding of Cm39 w
Externí odkaz:
https://doaj.org/article/67ed73345b9a4bbebdcd2538b18b25d0
Autor:
Muhammad Umair Naseem, Edson Carcamo-Noriega, José Beltrán-Vidal, Jesus Borrego, Tibor G. Szanto, Fernando Z. Zamudio, Gustavo Delgado-Prudencio, Lourival D. Possani, Gyorgy Panyi
Publikováno v:
The Journal of general physiology. 154(8)
The Cm28 in the venom of Centruroides margaritatus is a short peptide consisting of 27 amino acid residues with a mol wt of 2,820 D. Cm28 has 100× Kd value for KV1.3) did not inhibit KV1.5, KV11.1, KCa1.1, and KCa3.1 K+ channels; NaV1.5 and NaV1.4 N
Autor:
Ferenc Papp, Gilman E. S. Toombes, Zoltán Pethő, Adrienn Bagosi, Adam Feher, János Almássy, Jesús Borrego, Ákos Kuki, Sándor Kéki, Gyorgy Panyi, Zoltan Varga
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Fluorometry signals indicating conformational change in an ion channel are generated by quenching amino acids and lipid effects during movement of the dye relative to the plane of the membrane.
Externí odkaz:
https://doaj.org/article/7f7b2f17186c408295029866185e676f
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Este relatório de estágio foi realizado no âmbito das unidades curriculares de Prática de Ensino Supervisionada I e II em Creche e Jardim de Infância do mestrado em Educação Pré-Escolar. Tem como finalidade descrever e aprofundar as expressõ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::59ed47cf7afac27b61433efc84d5b27e
Autor:
Muhammad Umair Naseem, Gabor Tajti, Attila Gaspar, Tibor G. Szanto, Jesús Borrego, Gyorgy Panyi
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Margatoxin (MgTx) is a high-affinity blocker of voltage-gated potassium (Kv) channels. It inhibits Kv1.1–Kv1.3 ion channels in picomolar concentrations. This toxin is widely used to study physiological function of Kv ion channels in various cell ty
Externí odkaz:
https://doaj.org/article/b4c80743087e4d37a5242da8909296c6
Autor:
Jesús Borrego, Muhammad Umair Naseem, Al Nasar Ahmed Sehgal, Lipsa Rani Panda, Kashmala Shakeel, Attila Gaspar, Cynthia Nagy, Zoltan Varga, Gyorgy Panyi
Publikováno v:
Journal of Fungi, Vol 8, Iss 11, p 1215 (2022)
The Kv1.3 channel has become a therapeutic target for the treatment of various diseases. Several Kv1.3 channel blockers have been characterized from scorpion venom; however, extensive studies require amounts of toxin that cannot be readily obtained d
Externí odkaz:
https://doaj.org/article/e66c946cc5fc41abb7997fb4015c7f54
Autor:
Jesus Borrego
Publikováno v:
Contemporary Issues in Education Research (CIER). 3:59
Tighter budgets and lower enrollment are changing traditional higher education. The popularity of the World Wide Web (WWW) coupled with faster access to information provides an opportunity for Colleges and Universities to offer online programs. In mo
Autor:
Diana Alvarado, Samuel Cardoso-Arenas, Ligia-Luz Corrales-García, Herlinda Clement, Iván Arenas, Pavel Andrei Montero-Dominguez, Timoteo Olamendi-Portugal, Fernando Zamudio, Agota Csoti, Jesús Borrego, Gyorgy Panyi, Ferenc Papp, Gerardo Corzo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, ev
Externí odkaz:
https://doaj.org/article/f876414bce1e4318b0f8d8ae2745b2ad
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1303 (2021)
The human voltage gated potassium channel Kv1.5 that conducts the IKur current is a key determinant of the atrial action potential. Its mutations have been linked to hereditary forms of atrial fibrillation (AF), and the channel is an attractive targe
Externí odkaz:
https://doaj.org/article/7a8b7a19ab9449b59051c4ee818fb8a4
Publikováno v:
Winter Simulation Conference
This paper describes some of the issues involved in converting a prototype of a large-scale discrete event simulation written in SIMSCRIPT II.5 and FORTRAN into Ada. Specific features provided by SIMSCRIPT that needed to be created in Ada are discuss