Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jestinah. M. Mahachie John"'
Autor:
Fentaw Abegaz, François Van Lishout, Jestinah M. Mahachie John, Kridsadakorn Chiachoompu, Archana Bhardwaj, Diane Duroux, Elena S. Gusareva, Zhi Wei, Hakon Hakonarson, Kristel Van Steen
Publikováno v:
BioData Mining, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background In genome-wide association studies the extent and impact of confounding due to population structure have been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replicati
Externí odkaz:
https://doaj.org/article/f0fe96dca6664323a2f0574e5c262be1
Publikováno v:
BioData Mining, Vol 12, Iss 1, Pp 1-23 (2019)
Abstract Background In Genome-Wide Association Studies (GWAS), the concept of linkage disequilibrium is important as it allows identifying genetic markers that tag the actual causal variants. In Genome-Wide Association Interaction Studies (GWAIS), si
Externí odkaz:
https://doaj.org/article/7079e389d2fa4814aadad68b0100c97b
Publikováno v:
BioData Mining, Vol 15, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/6e77a314e51147ee9817bf885d4aa4ca
Autor:
Archana Bhardwaj, Elena S. Gusareva, Fentaw Abegaz, Zhi Wei, Kridsadakorn Chiachoompu, Jestinah M. Mahachie John, Diane Duroux, Hakon Hakonarson, Kristel Van Steen, François Van Lishout
Publikováno v:
BioData Mining, Vol 14, Iss 1, Pp 1-20 (2021)
BioData Mining
BioData Mining
BackgroundIn genome-wide association studies the extent and impact of confounding due to population structure have been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replication, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98825c13e33a0c6e98b524bbe4c175e2
https://doaj.org/article/f0fe96dca6664323a2f0574e5c262be1
https://doaj.org/article/f0fe96dca6664323a2f0574e5c262be1
Autor:
Bärbel Maus, Camille Jung, Jestinah M Mahachie John, Jean-Pierre Hugot, Emmanuelle Génin, Kristel Van Steen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77720 (2013)
Complex human diseases commonly differ in their phenotypic characteristics, e.g., Crohn's disease (CD) patients are heterogeneous with regard to disease location and disease extent. The genetic susceptibility to Crohn's disease is widely acknowledged
Externí odkaz:
https://doaj.org/article/f1fef2f499dd4bca9925a2f7bb3fbe43
Autor:
Fentaw Abegaz, Francois van Lishout, Jestinah M. Mahachie John, Kridsadakorn Chiachoompu, Archana Bhjardwa, Diane Duroux, Elena S. Gusareva, Zhi Wei, Hakon Hakonarson, Kristel Van Steen
Background In genome-wide association studies the extent and impact of confounding due population structure has been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replication and the id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb9208a0b73e429f8d62a21e8f47cfa
https://doi.org/10.21203/rs.3.rs-38377/v1
https://doi.org/10.21203/rs.3.rs-38377/v1
Autor:
Karin C Lødrup Carlsen, Stephanie Roll, Kai-Håkon Carlsen, Petter Mowinckel, Alet H Wijga, Bert Brunekreef, Maties Torrent, Graham Roberts, S Hasan Arshad, Inger Kull, Ursula Krämer, Andrea von Berg, Esben Eller, Arne Høst, Claudia Kuehni, Ben Spycher, Jordi Sunyer, Chih-Mei Chen, Andreas Reich, Anna Asarnoj, Carmen Puig, Olf Herbarth, Jestinah M Mahachie John, Kristel Van Steen, Stefan N Willich, Ulrich Wahn, Susanne Lau, Thomas Keil, GALEN WP 1.5 ‘Birth Cohorts’ working group
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43214 (2012)
ObjectiveTo examine the associations between pet keeping in early childhood and asthma and allergies in children aged 6-10 years.DesignPooled analysis of individual participant data of 11 prospective European birth cohorts that recruited a total of o
Externí odkaz:
https://doaj.org/article/2201a4e687c446e181373fd935d16835
Autor:
Jestinah M Mahachie John, Tom Cattaert, François Van Lishout, Elena S Gusareva, Kristel Van Steen
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29594 (2012)
Identifying gene-gene interactions or gene-environment interactions in studies of human complex diseases remains a big challenge in genetic epidemiology. An additional challenge, often forgotten, is to account for important lower-order genetic effect
Externí odkaz:
https://doaj.org/article/fdf7cb20fa834f029b1776d41c26599d
Autor:
David W. Fardo, Jestinah M. Mahachie John, Kridsadakorn Chaichoompu, Emmanuelle Génin, Fentaw Abegaz, Inke R. König, Kristel Van Steen
Publikováno v:
Briefings in Bioinformatics. 20:2200-2216
Principal components (PCs) are widely used in statistics and refer to a relatively small number of uncorrelated variables derived from an initial pool of variables, while explaining as much of the total variance as possible. Also in statistical genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994e570d3a61a0d035aa046373082de3
https://doi.org/10.1093/bib/bby081
https://doi.org/10.1093/bib/bby081
Autor:
Annett Maderer, Murielle Mauer, Carmela Caballero, Eric Van Cutsem, Thomas Thomaidis, István Láng, Markus Moehler, Arno Schad, João Freire, Jestinah. M. Mahachie John, Arnaud Roth, Ajlan Atasoy, Manfred P. Lutz
Publikováno v:
Cancer Chemotherapy and Pharmacology. 82:733-739
HER2-targeted therapy with trastuzumab and (CF/X) prolonged overall survival (OS) in metastatic HER2neu+ gastric carcinoma (GC). Lapatinib inhibits both EGFR and HER2neu. We investigated the efficacy and safety of lapatinib with epirubicin (E) + CF/X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7998b6d7537bf295f03fabe914de2cd6
https://doi.org/10.1007/s00280-018-3667-8
https://doi.org/10.1007/s00280-018-3667-8