Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jestin Chellian"'
Autor:
Anil Philip Kunnath, Mohamed Suodha Suoodh, Dinesh Kumar Chellappan, Jestin Chellian, Kishneth Palaniveloo
Publikováno v:
British Journal of Biomedical Science, Vol 81 (2024)
The global issue of antimicrobial resistance poses significant challenges to public health. The World Health Organization (WHO) has highlighted it as a major global health threat, causing an estimated 700,000 deaths worldwide. Understanding the multi
Externí odkaz:
https://doaj.org/article/00d28cb6309f45cc8111eb21a0008c55
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The present work examined the effect of oral administration of rutin and its combination with metformin, an antidiabetic drug on blood glucose, total cholesterol and triglycerides level and vascular function in streptozotocin (STZ) -induced
Externí odkaz:
https://doaj.org/article/f1b0bb210b794f0f88a4189d18547d22
Autor:
Jestin Chellian, Kit-Kay Mak, Dinesh Kumar Chellappan, Purushotham Krishnappa, Mallikarjuna Rao Pichika
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The antidiabetic effects of quercetin and metformin are well known. However, their synergistic effect in reversing the symptoms of diabetes-induced endothelial dysfunction remains unknown. In this study, we have investigated their synergisti
Externí odkaz:
https://doaj.org/article/5f81b93e93af4cf1bf22ea92339c3497
Autor:
Nilesh Kumar Mitra, Nermesh Singh A/L Gurdib Singh, Nurul Ain Najihah Binti Wadingasafi, Jestin Chellian
Publikováno v:
Research in Pharmaceutical Sciences, Vol 17, Iss 2, Pp 134-142 (2022)
Background and purpose: Fingolimod is a sphingosine 1-phosphate receptor modulator used to treat multiple sclerosis (MS). Alpha-tocopherol (AT) has been found to improve motor function in an animal model of MS. In the present study, the effects of AT
Externí odkaz:
https://doaj.org/article/9e11565387314c13bbba1450a3b32eda
Autor:
Kit-Kay Mak, Shiming Zhang, Jestin Chellian, Zulkefeli Mohd, Ola Epemolu, Albena T. Dinkova-Kostova, Madhu Katyayani Balijepalli, Mallikarjuna Rao Pichika
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 595 (2023)
Our previous studies have reported the effect of swietenine (a major bioactive component of Swietenia macrophylla seeds) in reversing and potentiating the effect of metformin in hyperglycemia and hyperlipidaemia in diabetic rats. Moreover, we reporte
Externí odkaz:
https://doaj.org/article/15fd1e664fdd4628866da7349dda3c74
Autor:
Nilesh Kumar Mitra, Kong Yu Xuan, Charmaine Caryn Teo, Ng Xian-Zhuang, Anudeep Singh, Jestin Chellian
Publikováno v:
Research in Pharmaceutical Sciences, Vol 15, Iss 6, Pp 602-611 (2020)
Background and Purpose: Multiple sclerosis (MS) is an autoimmune disorder characterized by demyelination and axonal loss. Quantitative estimation of behavioral, locomotor, and histological changes following the use of alpha-tocopherol (AT) in the ani
Externí odkaz:
https://doaj.org/article/1eec01f7c92b406e9a2739e424c21c77
Autor:
Kishneth Palaniveloo, Liaw Yee-Yinn, Leong Jia-Qi, Alvin Chelliah, Song Sze-Looi, Thilahgavani Nagappan, Shariza Abdul Razak, Kamal Dua, Jestin Chellian, Dinesh Kumar Chellappan, Anil Philip Kunnath
Publikováno v:
Foods, Vol 10, Iss 8, p 1932 (2021)
Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsul
Externí odkaz:
https://doaj.org/article/8dd8e0238fea45a7af50916f85d74399
Autor:
Abdul Qudus B Aroyehun, Shariza Abdul Razak, Kishneth Palaniveloo, Thilahgavani Nagappan, Nur Suraiza Nabila Rahmah, Gan Wee Jin, Dinesh Kumar Chellappan, Jestin Chellian, Anil Philip Kunnath
Publikováno v:
Foods, Vol 9, Iss 9, p 1313 (2020)
Caulerpa racemosa (Forsskal) J. Agardh is a green seaweed used as food and folk medicine since ancient times in the Indo-Pacific region, particularly in southeast Asia. In this study, the proximate nutrient composition, phytochemical, anti-oxidant an
Externí odkaz:
https://doaj.org/article/6befff02a3b844f7b55c9d4bcba6ba6d
Publikováno v:
Pharmaceutics, Vol 8, Iss 3, p 27 (2016)
The goal of this study was to formulate and evaluate side effects of transdermal delivery of proniosomal gel compared to oral tolterodine tartrate (TT) for the treatment of overactive bladder (OAB). Proniosomal gels are surfactants, lipids and soy le
Externí odkaz:
https://doaj.org/article/4ba7cbbade254f418e5801efac40fa78
Autor:
Dinesh Kumar Chellappan, Keshav Raj Paudel, Nian Wan Tan, Ka Seng Cheong, Samantha Sert Qi Khoo, Su Min Seow, Jestin Chellian, Mayuren Candasamy, Vyoma K. Patel, Poonam Arora, Pankaj Kumar Singh, Sachin Kumar Singh, Gaurav Gupta, Brian G. Oliver, Philip M. Hansbro, Kamal Dua
Publikováno v:
Mitochondrion. 67:15-37
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also the source of respiratory ATP. Recently published studies have demonstrated that mitochondria may have more roles to play aside from energy production. Th