Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Jessy S Deshane"'
Autor:
Diptiman Chanda, Mohammad Rehan, Samuel R Smith, Kevin G Dsouza, Yong Wang, Karen Bernard, Deepali Kurundkar, Vinayak Memula, Kyoko Kojima, James A Mobley, Gloria A Benavides, Victor Darley-Usmar, Young-iL Kim, Jaroslaw W Zmijewski, Jessy S Deshane, Stijn De Langhe, Victor J Thannickal
Publikováno v:
eLife, Vol 10 (2021)
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form t
Externí odkaz:
https://doaj.org/article/ef49c5e79b324a57988570b54d4ab9ff
Autor:
Shaheer Ahmad, Sierra Single, Yuelong Liu, Kenneth P. Hough, Yong Wang, Victor J. Thannickal, Mohammad Athar, Kayla F. Goliwas, Jessy S. Deshane
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 978 (2024)
Exposure to heavy metals (HMs) is often associated with inflammation and cell death, exacerbating respiratory diseases including asthma. Most inhaled particulate HM exposures result in the deposition of HM-bound fine particulate matter, PM2.5, in pul
Externí odkaz:
https://doaj.org/article/d607257caa89471f9b00c2e471025d23
Autor:
Rabisa J. Khan, Sierra L. Single, Christopher S. Simmons, Mohammad Athar, Yuelong Liu, Sandeep Bodduluri, Paul V. Benson, Kayla F. Goliwas, Jessy S. Deshane
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe SARS-CoV-2 mediated COVID-19 pandemic has impacted millions worldwide. Hyper-inflammatory processes, including cytokine storm, contribute to long-standing tissue injury and damage in COVID-19. The metabolism of sphingolipids as regula
Externí odkaz:
https://doaj.org/article/985505055dd346e79bc00c0ebd3d84d0
Autor:
Lin Jin, Mahendra P. Kashyap, Yunjia Chen, Jasim Khan, Yuanyuan Guo, Jari Q. Chen, Madison B. Lee, Zhiping Weng, Allen Oak, Prasanth Patcha, Tiffany Mayo, Rajesh Sinha, Venkatram Atigadda, Shahid M. Mukhtar, Jessy S. Deshane, Chander Raman, Carly Elston, Boni E. Elewski, Craig A. Elmets, Mohammad Athar
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106896- (2023)
Summary: Hidradenitis suppurativa (HS) is a skin disorder that causes chronic painful inflammation and hyperproliferation, often with the comorbidity of invasive keratoacanthoma (KA). Our research, employing high-resolution immunofluorescence and dat
Externí odkaz:
https://doaj.org/article/0de4db9502ab4617909eb859b7c9b5e5
Autor:
Jeffery C. Bloodworth, Aki Hoji, Garen Wolff, Rabindra K. Mandal, Nathan W. Schmidt, Jessy S. Deshane, Casey D. Morrow, Kirsten M. Kloepfer, Joan M. Cook-Mills
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
In humans and animals, offspring of allergic mothers have increased responsiveness to allergens. This is blocked in mice by maternal supplementation with α-tocopherol (αT). Also, adults and children with allergic asthma have airway microbiome dysbi
Externí odkaz:
https://doaj.org/article/7b2281d87b2643e8860144b949b14de0
Autor:
Nirmal S. Sharma, Grant Vestal, Keith Wille, Kapil N. Patel, Feng Cheng, Srinivas Tipparaju, Sultan Tousif, Mudassir M. Banday, Xin Xu, Landon Wilson, Viswam S. Nair, Casey Morrow, Don Hayes, Andreas Seyfang, Stephen Barnes, Jessy S. Deshane, Amit Gaggar
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Recent studies suggest that alterations in lung microbiome are associated with occurrence of chronic lung diseases and transplant rejection. To investigate the host-microbiome interactions, we characterized the airway microbiome a
Externí odkaz:
https://doaj.org/article/ee6dbc5caa644141830ae453048e3ee1
Autor:
Sultan Tousif, Yong Wang, Joshua Jackson, Kenneth P. Hough, John G. Strenkowski, Mohammad Athar, Victor J. Thannickal, Robert H. McCusker, Selvarangan Ponnazhagan, Jessy S. Deshane
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory B cells (Breg) are IL-10 producing subsets of B cells that contribute to immunosuppression in the tumor microenvironment (TME). Breg are elevated in patients with lung cancer; however, the mechanisms underlying Breg development and their f
Externí odkaz:
https://doaj.org/article/1942612f213d4139803771b8c0d5424a
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sphingolipids are bioactive lipids involved in the regulation of cell survival, proliferation, and the inflammatory response. The SphK/S1P/S1PR pathway (S1P pathway) is a driver of many anti-apoptotic and proliferative processes. Pro-survival sphingo
Externí odkaz:
https://doaj.org/article/6c3d1f4038a74febbdc40bbd6434b98c
Autor:
Gregory J. Smith, Adelaide Tovar, Matt Kanke, Yong Wang, Jessy S. Deshane, Praveen Sethupathy, Samir N. P. Kelada
Publikováno v:
Physiological Reports, Vol 9, Iss 18, Pp n/a-n/a (2021)
Abstract Inhalation exposure to ozone (O3) causes adverse respiratory health effects that result from airway inflammation, a complex response mediated in part by changes to airway cellular transcriptional programs. These programs may be regulated by
Externí odkaz:
https://doaj.org/article/591db62d95fa4201a077f19059949e37
Autor:
Kayla F. Goliwas, Hannah M. Ashraf, Anthony M. Wood, Yong Wang, Kenneth P. Hough, Sandeep Bodduluri, Mohammad Athar, Joel L. Berry, Selvarangan Ponnazhagan, Victor J. Thannickal, Jessy S. Deshane
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we develo
Externí odkaz:
https://doaj.org/article/90f97a9bf0e049c8b01cac94dcb42e54