Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jessy Elizabeth Mathew"'
Autor:
Keloth Kaitheri Srinivasan, Jessy Elizabeth Mathew, Kerryn Joseph A.D’Silva, Richard Lobo, Nimmy Kumar
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 18, Iss 4, Pp 412-416 (2015)
Objective(s):To evaluate the effect of Graptophyllum pictum on lipid peroxidation and tissue antioxidant enzymes in liver and kidney of gentamicin induced nephrotoxic rats. Materials and Methods: Animals were grouped into 6: Group 1 received gum acac
Externí odkaz:
https://doaj.org/article/1a53f9cd82394e8fa675e85c84a4fe9c
Autor:
Jetta Sandeep Kumar, B. Thirupataiah, Jayesh Mudgal, Gangireddy Sujeevan Reddy, Guntipally Mounika, Kazi Amirul Hossain, Marina Rajadurai, Jessy Elizabeth Mathew, Gautham G. Shenoy, Kishore V. L. Parsa, Manojit Pal
Publikováno v:
Chemical Communications. 57:10091-10094
A Pd-catalysed regioselective synthesis of 4,5-disubstituted 7-membered N/O-heterocycles was achieved via the 7-endo-dig cyclization followed by C–C bond formation of 2-(1-alkynyl)phenylacetamide. The ligand/additive free cascade reaction proceeded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c47dc332e07b7b9ffdfb20caeab9f3a
https://doi.org/10.1039/d1cc04140a
https://doi.org/10.1039/d1cc04140a
Publikováno v:
Rasayan Journal of Chemistry. 13:2281-2289
Mistletoes have earned a strong profile in treating cancer. Elytranthe parasitica (L.) Danser (EP), a hemi-parasitic plant belonging to Mistletoe family or Loranthaceae is known for its potent anti-cancer properties. Exploring the phytochemistry by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb51db135e7a6792a78fdb59b833ebcc
https://doi.org/10.31788/rjc.2020.1346062
https://doi.org/10.31788/rjc.2020.1346062
Autor:
Kishore V. L. Parsa, Jayesh Mudgal, E.V.V. Shivaji Ramarao, Jetta Sandeep Kumar, Ramudu Bankala, Hari Maduri Doss, Mahaboobkhan Rasool, Manojit Pal, Rajnikanth Sunke, Pushkar Kulkarni, B. Thirupataiah, Ravikumar Kapavarapu, Gautham G. Shenoy, Raghavender Medishetti, Jessy Elizabeth Mathew
Publikováno v:
European Journal of Medicinal Chemistry. 174:198-215
A new class of PDE4 inhibitors were designed and synthesized via the InCl3 mediated heteroarylation of indoles and their further derivatization through the Pd(II)-catalyzed C H activation strategy. This effort allowed us to discover a series of 2-(1H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aec68d5d4d21d2e7d1057a76f345800
https://doi.org/10.1016/j.ejmech.2019.04.020
https://doi.org/10.1016/j.ejmech.2019.04.020
Autor:
Akhila Hosur Shrungeswara, Krishnadas Nandakumar, Subhankar Biswas, Jessy Elizabeth Mathew, Jesil Mathew, Sanchari Basu Mallik, Richard Lobo, Nimmy Kumar
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 18:1563-1572
Background: Hepatocellular carcinoma (HCC) is the fifth leading cause of cáncer mortality. Elytranthe parasitica (L.) Danser (EP), a hemiparasitic plant (Loranthaceae) has potent anti-cancer properties. Objective: In the study, we investigated the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92eec84b0b600ccf72e24bf6476e0017
https://doi.org/10.2174/1871520618666180911112127
https://doi.org/10.2174/1871520618666180911112127
Autor:
Gautham G. Shenoy, Kazi Amirul Hossain, C. Mallikarjuna Rao, Gangireddy Sujeevan Reddy, Raghavender Medishetti, Mahaboobkhan Rasool, Kishore V. L. Parsa, Manojit Pal, Guntipally Mounika, Jetta Sandeep Kumar, Jayesh Mudgal, Kiranam Chatti, B. Thirupataiah, Snigdha Samarpita, Jessy Elizabeth Mathew
Publikováno v:
European Journal of Medicinal Chemistry. 221:113514
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing an aminosulfony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6eb1ed69873e7de4a41198910caf90b
https://doi.org/10.1016/j.ejmech.2021.113514
https://doi.org/10.1016/j.ejmech.2021.113514
Autor:
Raghavender Medishetti, Jayesh Mudgal, B. Thirupataiah, Ravikumar Kapavarapu, Kishore V. L. Parsa, Jetta Sandeep Kumar, Guntipally Mounika, Gautham G. Shenoy, Manojit Pal, Kiranam Chatti, Gangireddy Sujeevan Reddy, Jessy Elizabeth Mathew, C. Mallikarjuna Rao
Publikováno v:
Bioorganic Chemistry. 115:105265
In spite of possessing a wide range of pharmacological properties the anti-inflammatory activities of isoquinolin-1(2H)-ones were rarely known or explored earlier. PDE4 inhibitors on the other hand in addition to their usefulness in treating inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9add33a7f9372d800168c8c55356f87d
https://doi.org/10.1016/j.bioorg.2021.105265
https://doi.org/10.1016/j.bioorg.2021.105265
Autor:
Subhankar Biswas, Jesil Mathew, Krishnadas Nandakumar, Sanchari Basu Mallik, Akhila Hosur Shrungeswara, Jessy Elizabeth Mathew, Richard Lobo, Mathew Hipolith Viji, Nimmy Kumar
Publikováno v:
Journal of Infection and Chemotherapy. 23:354-359
Colorectal cancer (CRC) is a highly predominant malignancy affecting millions worldwide. Plants belonging to Loranthaceae family have remarkable chemopreventive properties.The goal of the present study was to assess the antiproliferative and apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5e043a11d23909bf0609c821afc733
https://doi.org/10.1016/j.jiac.2017.02.009
https://doi.org/10.1016/j.jiac.2017.02.009
Autor:
Sagar P. Nehate, Girij Pal Singh, Himanshu M. Godbole, Gautham G. Shenoy, Jessy Elizabeth Mathew
Novel chiral imidazolium and pyridinium ionic liquids based on tartaric acid and 2-oxazolidinone were designed. Symmetrical dicationic ionic liquids based on tartaric acid have been synthesized and characterized. These chiral ionic liquids were desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f617a6e4a39c6be7eeab6d8735e5b92a
Autor:
Gangireddy Sujeevan Reddy, B. Thirupataiah, Shailendra S. Ghule, Jetta Sandeep Kumar, Jessy Elizabeth Mathew, Manojit Pal, Gautham G. Shenoy, Kazi Amirul Hossain, Jayesh Mudgal, Guntipally Mounika, Kishore V. L. Parsa
Publikováno v:
Bioorganic Chemistry. 97:103691
In spite of their various pharmacological properties the anti-inflammatory potential of benzo[c]phenanthridines remained underexplored. Thus, for the first time PDE4 inhibitory potential of 11,12-dihydro benzo[c]phenanthridine/benzo[c]phenanthridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::383e75894a29b319bc60ad0456e02af9
https://doi.org/10.1016/j.bioorg.2020.103691
https://doi.org/10.1016/j.bioorg.2020.103691