Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jessy A. Slota"'
Publikováno v:
Prion, Vol 17, Iss 1, Pp 116-132 (2023)
ABSTRACTPrions are misfolded proteins that accumulate within the brain in association with a rare group of fatal and infectious neurological disorders in humans and animals. A current challenge to research is a lack of in vitro model systems that are
Externí odkaz:
https://doaj.org/article/f463c871e0d94d7480db5231782a1048
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-23 (2022)
Abstract Prion diseases are neurodegenerative disorders with long asymptomatic incubation periods, followed by a rapid progression of cognitive and functional decline culminating in death. The complexity of intercellular interactions in the brain is
Externí odkaz:
https://doaj.org/article/eb6491552a6b4206b5e093e1db4ba8c3
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elusive. Here, we used RNAseq to profile transcription
Externí odkaz:
https://doaj.org/article/b93e609511584e249384707caaf117e3
Autor:
Jessy A. Slota, Sarah J. Medina, Megan Klassen, Damian Gorski, Christine M. Mesa, Catherine Robertson, Gordon Mitchell, Michael B. Coulthart, Sandra Pritzkow, Claudio Soto, Stephanie A. Booth
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Chronic wasting disease (CWD) is an emerging infectious prion disorder that is spreading rapidly in wild populations of cervids in North America. The risk of zoonotic transmission of CWD is as yet unclear but a high priority must be to minim
Externí odkaz:
https://doaj.org/article/af040d673aa34dee92178211e6bf509e
Autor:
Lise Lamoureux, Babu Sajesh, Jessy A. Slota, Sarah J. Medina, Matthew Mayor, Kathy L. Frost, Bryce Warner, Kathy Manguiat, Heidi Wood, Darwyn Kobasa, Stephanie A. Booth
Publikováno v:
Viruses, Vol 14, Iss 6, p 1218 (2022)
The numerous neurological syndromes associated with COVID-19 implicate an effect of viral pathogenesis on neuronal function, yet reports of direct SARS-CoV-2 infection in the brain are conflicting. We used a well-established organotypic brain slice c
Externí odkaz:
https://doaj.org/article/c6ad9fd4d82c42a2bae92b7388f370d4
Autor:
Jessy A. Slota, Stephanie A. Booth
Publikováno v:
Non-Coding RNA, Vol 5, Iss 2, p 35 (2019)
The central nervous system can respond to threat via the induction of an inflammatory response. Under normal circumstances this response is tightly controlled, however uncontrolled neuroinflammation is a hallmark of many neurological disorders. Micro
Externí odkaz:
https://doaj.org/article/fb6753287f40426084c21bba45f06264
Autor:
Robert A. Kozak, Anna Majer, Mia J. Biondi, Sarah J. Medina, Lee W. Goneau, Babu V. Sajesh, Jessy A. Slota, Vanessa Zubach, Alberto Severini, David Safronetz, Shannon L. Hiebert, Daniel R. Beniac, Timothy F. Booth, Stephanie A. Booth, Gary P. Kobinger
Publikováno v:
Viruses, Vol 9, Iss 10, p 297 (2017)
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain
Externí odkaz:
https://doaj.org/article/f73cef91f47e4b3e82a2eb0ebbce497a
Autor:
Damian Gorski, Megan Klassen, Claudio Soto, Michael B. Coulthart, Jessy A Slota, Sandra Pritzkow, Gordon Mitchell, Stephanie A. Booth, Catherine Robertson, Sarah J. Medina, Christine Mesa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Chronic wasting disease (CWD) is an emerging infectious prion disorder that is spreading rapidly in wild populations of cervids in North America. The risk of zoonotic transmission of CWD is as yet unclear but a high priority must be to minimize furth
Autor:
Gary P. Kobinger, Shannon L. Hiebert, Stephanie A. Booth, Sarah J. Medina, Timothy F. Booth, Vanessa Zubach, Lee W. Goneau, Robert A. Kozak, Jessy A Slota, Anna Majer, Daniel R. Beniac, David Safronetz, Mia J. Biondi, Alberto Severini, Babu V Sajesh
Publikováno v:
Viruses; Volume 9; Issue 10; Pages: 297
Viruses
Viruses, Vol 9, Iss 10, p 297 (2017)
Viruses
Viruses, Vol 9, Iss 10, p 297 (2017)
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain