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pro vyhledávání: '"Jessie Rose Davis"'
Autor:
Luke W. Koblan, Peter J. Chen, Alexander A. Sousa, Aditya Raguram, Peyton B. Randolph, Gregory A. Newby, Jonathan M. Levy, Andrew V. Anzalone, Christine D. Wilson, David R. Liu, Jessie Rose Davis
Publikováno v:
Nature
Most genetic variants that contribute to disease1 are challenging to correct efficiently and without excess byproducts2-5. Here we describe prime editing, a versatile and precise genome editing method that directly writes new genetic information into
Autor:
David R. Liu, Jason Comander, Erin Hennessey, Jonathan M. Levy, Wei-Hsi Yeh, Luke W. Koblan, Rossano Butcher, Nachiket D. Pendse, Jessie Rose Davis, Qin Liu
Publikováno v:
Nature biomedical engineering
The success of base editors for the study and treatment of genetic diseases depends on the ability to deliver them in vivo to the relevant cell types. Delivery via adeno-associated viruses (AAVs) is limited by AAV-packaging capacity, which precludes