Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jessie Nicodemus‐Johnson"'
Autor:
Steven E. Arnold, Suzanne Hendrix, Jessie Nicodemus‐Johnson, Newman Knowlton, Victoria J. Williams, Jeffrey M. Burns, Monica Crane, Alison J. McManus, Sanjeev N. Vaishnavi, Zoe Arvanitakis, Judith Neugroschl, Karen Bell, Bianca A. Trombetta, Becky C. Carlyle, Pia Kivisäkk, Hiroko H. Dodge, Rudolph E. Tanzi, Patrick D. Yeramian, Kent Leslie
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Sodium phenylbutyrate and taurursodiol (PB and TURSO) is hypothesized to mitigate endoplasmic reticulum stress and mitochondrial dysfunction, two of many mechanisms implicated in Alzheimer's disease (AD) pathophysiology. METHODS
Externí odkaz:
https://doaj.org/article/094dc11770e44f12a0e5cddf65670bfc
Autor:
Mihály Hajós, Alyssa Boasso, Evan Hempel, Monika Shpokayte, Alex Konisky, Chandran V. Seshagiri, Vitella Fomenko, Kim Kwan, Jessie Nicodemus-Johnson, Suzanne Hendrix, Brent Vaughan, Ralph Kern, Jonathan T. Megerian, Zach Malchano
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAlzheimer’s Disease (AD) is a multifactorial, progressive neurodegenerative disease that disrupts synaptic and neuronal activity and network oscillations. It is characterized by neuronal loss, brain atrophy and a decline in cognitive and
Externí odkaz:
https://doaj.org/article/bb3fd91a80ed4b38ba3e063f0a855f5c
Autor:
Samuel P. Dickson, Suzanne B. Hendrix, Bruce L. Brown, Perry G. Ridge, Jessie Nicodemus‐Johnson, Marci L. Hardy, Allison M. McKeany, Steven B. Booth, Ryan R. Fortna, John S.K. Kauwe, NIAGADS
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Recent clinical trials are considering inclusion of more than just apolipoprotein E (APOE) ε4 genotype as a way of reducing variability in analysis of outcomes. Methods Case‐control data were used to compare the capacity of a
Externí odkaz:
https://doaj.org/article/dcdf227c6d794923a58f7d1ee6100666
Autor:
Emma E. Thompson, Jessie Nicodemus-Johnson, Kyung Won Kim, James E. Gern, Daniel J. Jackson, Robert F. Lemanske, Carole Ober
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background The changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental fact
Externí odkaz:
https://doaj.org/article/87c7f3952723442893fa3df535cc3427
Autor:
Xiaohui Guo, Yifan Xu, Hairong He, Hao Cai, Jianfen Zhang, Yibin Li, Xinyu Yan, Man Zhang, Na Zhang, Rolando L. Maddela, Jessie Nicodemus-Johnson, Guansheng Ma
Publikováno v:
Journal of Obesity, Vol 2018 (2018)
Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically
Externí odkaz:
https://doaj.org/article/e2d1ad2b3d69433aac44058214ee5654
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132474 (2015)
In the heart, scaffolding proteins such as A-Kinase Anchoring Proteins (AKAPs) play a crucial role in normal cellular function by serving as a signaling hub for multiple protein kinases including protein kinase D1 (PKD1). Under cardiac hypertrophic c
Externí odkaz:
https://doaj.org/article/9fe7c9ea9ab04da79d951301ae5e2d78
Autor:
Samuel P. Dickson, Sean Hennessey, Jessie Nicodemus Johnson, Newman Knowlton, Suzanne B. Hendrix
Publikováno v:
Alzheimer's Research & Therapy. 15
Key points of disagreement between the aducanumab FDA statistical review, which had primarily negative conclusions, and the clinical review, which had primarily positive conclusions, were investigated. Results from secondary endpoints in positive Stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::956e5a646ff1b8e2389de7099ed450e3
https://doi.org/10.1186/s13195-023-01238-1
https://doi.org/10.1186/s13195-023-01238-1
Autor:
Suzanne B. Hendrix, Jessie Nicodemus‐Johnson, Nathaniel J. Hogan, Newman Knowlton, Sean Hennessey, Samuel P. Dickson
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 18
The most followed investigational treatments for Alzheimer's disease are small molecules (80/140 in development, 57%) and immunotherapies (32/140, 23%). These treatments have a clear regulatory path and are based on innovative scientific approaches t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6810f4848c25394fb7242c03b6903372
https://pubmed.ncbi.nlm.nih.gov/36537965
https://pubmed.ncbi.nlm.nih.gov/36537965
Autor:
Samuel P. Dickson, Nathaniel J. Hogan, Jessie Nicodemus‐Johnson, Newman Knowlton, Sean Hennessey, Suzanne B. Hendrix
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f012fc136a5f6f4677cf9aa2c0c5637
https://doi.org/10.1002/alz.068296
https://doi.org/10.1002/alz.068296
Autor:
Kevin M. Magnaye, Selene M. Clay, Jessie Nicodemus-Johnson, Katherine A. Naughton, Janel Huffman, Matthew C. Altman, Daniel J. Jackson, James E. Gern, Douglas K. Hogarth, Edward T. Naureckas, Steven R. White, Carole Ober
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(24)
Maternal asthma (MA) is among the most consistent risk factors for asthma in children. Possible mechanisms for this observation are epigenetic modifications in utero that have lasting effects on developmental programs in children of mothers with asth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6f64cbd06b38053fe59087e9cb27fb
https://pubmed.ncbi.nlm.nih.gov/35666868
https://pubmed.ncbi.nlm.nih.gov/35666868