Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jessie Hao-Ru Hsu"'
Autor:
Cornelia von Levetzow, Xiaohua Jiang, Ynnez Gwye, Gregor von Levetzow, Long Hung, Aaron Cooper, Jessie Hao-Ru Hsu, Elizabeth R Lawlor
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19305 (2011)
Ewing sarcoma family tumors (ESFT) are aggressive bone and soft tissue tumors that express EWS-ETS fusion genes as driver mutations. Although the histogenesis of ESFT is controversial, mesenchymal (MSC) and/or neural crest (NCSC) stem cells have been
Externí odkaz:
https://doaj.org/article/60c32db8fc7b4c2c8959a9a49c4ab72a
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
This file contains additional data supporting the role of Prmt1 in human OS maintenance and murine OS tumor initiation, as well as proteomics and RNA-seq data supporting the role of Prmt1 in translation regulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc405853c965ca6887891445f505e68
https://doi.org/10.1158/0008-5472.22414200
https://doi.org/10.1158/0008-5472.22414200
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
GSEA analysis of differentially expressed genes in the control versus Prmt1 KO mOS at the transcript level using hallmark gene sets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9dc5166fd026b5035a05c6deaf0c47
https://doi.org/10.1158/0008-5472.22414191
https://doi.org/10.1158/0008-5472.22414191
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
Function enrichment of down regulated genes upon Prmt1 depletion at the translation level using DAVID functional annotation tool (GO BP_direct).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f860b184adabe975fa4e8b37a90023
https://doi.org/10.1158/0008-5472.22414188.v1
https://doi.org/10.1158/0008-5472.22414188.v1
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
Through an shRNA screen, we identified the protein arginine methyltransferase Prmt1 as a vulnerable intervention point in murine p53/Rb-null osteosarcomas, the human counterpart of which lacks effective therapeutic options. Depletion of Prmt1 in p53-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e0c622452115bcf0273791f0f27a90
https://doi.org/10.1158/0008-5472.c.6508908
https://doi.org/10.1158/0008-5472.c.6508908
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
GSEA analysis of differentially expressed genes in the control versus Prmt1 KO mOS at the transcript level using GO gene sets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b76b3b823a5f05c3c21c37cfa17ed4
https://doi.org/10.1158/0008-5472.22414194.v1
https://doi.org/10.1158/0008-5472.22414194.v1
Supplementary method from PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
Supplementary proteomics method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7772f2124707646faf4f013518659a5
https://doi.org/10.1158/0008-5472.22414182.v1
https://doi.org/10.1158/0008-5472.22414182.v1
Autor:
Stuart H. Orkin, Jarrod A. Marto, William C. Hahn, Carl D. Novina, Woojin Kim, Huafeng Xie, Glenn S. Cowley, Yuko Fujiwara, Jennifer Trowbridge, Jennifer A. Perry, Andrew O. Giacomelli, Aviad Tsherniak, Philip Montgomery, Barbara A. Weir, Francisca Vazquez, Cailin E. Joyce, Jialiang Huang, Guillaume Adelmant, Benjamin Hubbell-Engler, Jessie Hao-Ru Hsu
GSEA analysis of gene dependencies that correlate with Prmt1 dependency in the human Project Achilles dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a698d61ba144412f9650b5c38bffb77
https://doi.org/10.1158/0008-5472.22414185
https://doi.org/10.1158/0008-5472.22414185
Autor:
Elizabeth R. Lawlor, Timothy J. Triche, Hiro Shimada, Grace Peng, John van Doorninck, Diana Abdueva, Aaron Cooper, Long Hung, Jessie Hao-Ru Hsu, Dorothea Douglas
Supplementary Table 1 from BMI-1 Promotes Ewing Sarcoma Tumorigenicity Independent of CDKN2A Repression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fdca642613703551bf0933deacffe1
https://doi.org/10.1158/0008-5472.22374659.v1
https://doi.org/10.1158/0008-5472.22374659.v1
Autor:
Elizabeth R. Lawlor, Timothy J. Triche, Hiro Shimada, Grace Peng, John van Doorninck, Diana Abdueva, Aaron Cooper, Long Hung, Jessie Hao-Ru Hsu, Dorothea Douglas
Deregulation of the polycomb group gene BMI-1 is implicated in the pathogenesis of many human cancers. In this study, we have investigated if the Ewing sarcoma family of tumors (ESFT) expresses BMI-1 and whether it functions as an oncogene in this hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9757821fd70b3eb0ada15e767ac5d296
https://doi.org/10.1158/0008-5472.c.6497537
https://doi.org/10.1158/0008-5472.c.6497537