Výsledky vyhledávání - "Jessie (Jingjing) Wang"

Abstract 5134: PD-1/PD-L1 signalling axis, 'a double-edged sword' in DSS induced colitis mouse model

Autor: Tao Yang, Rongfei Lu, kaixia lian, Likun Zhang, Dawei Wang, Xinhe Feng, Xiaoyu An, Jessie (Jingjing) Wang, Carl K. Edwards

Publikováno v: Cancer Research. 83:5134-5134

Background. Immune checkpoint molecules are essential for modulating immune responses and maintaining self-tolerance. While immune checkpoint inhibitors have improved the treatment of a broad spectrum of cancers, many of them are also believed to pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::002a4f2c2e1d080938b0e10618135c10
https://doi.org/10.1158/1538-7445.am2023-5134

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Abstract 5133: Oxazolone induced atopic dermatitis mouse model using hIL-4/hIL-4Ra double knock-in mice, a preclinical mouse model for evaluating Dupilumab biosimilars

Autor: Tao Yang, Rongfei Lu, Xiaofei Xu, Likun Zhang, Dawei Wang, Xinhe Feng, Xiaoyu An, Jessie (Jingjing) Wang, Xianfei He, Carl K. Edwards

Publikováno v: Cancer Research. 83:5133-5133

Background. Th2 cytokines (e.g. IL-4, IL-5, IL13) drive defined allergic reactions and various autoimmune and inflammatory diseases including atopic dermatitis (AD), asthma and rhinitis. IL-4Ra is a receptor shared by both IL-4 and IL-13, thus blocki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ce7e5f2004800d4c0cacdf431f7cefe
https://doi.org/10.1158/1538-7445.am2023-5133

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Abstract P005: Establishment and characterization of a panel of advanced prostate cancer patient-derived xenograft (PDX) models for cancer therapeutic evaluation

Autor: Jessie Jingjing Wang, Leilei Chen, Xueying Yang, Likun Zhang, Wubin Qian, Henry Qixiang Li

Publikováno v: Molecular Cancer Therapeutics. 20:P005-P005

Background: Prostate cancer is one of the most frequently diagnosed solid malignancies and is accountable for the second highest cancer-related deaths in males worldwide. Despite the success of targeting the androgen receptor signaling pathway with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc9d7c3d58e09f800f330c3e56ff0ab8
https://doi.org/10.1158/1535-7163.targ-21-p005

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Abstract 4621: Developing genetically modified homograft models of mouse prostate cancer for efficacy evaluation of combinatory immunotherapies

Autor: Jessie Jingjing Wang, Yanrui Song, Annie Xiaoyu An, Likun Zhang, Henry Qixiang Li, Davy Xuesong Ouyang

Publikováno v: Cancer Research. 79:4621-4621

Despite the early approval of Sipuleucel-T for metastatic castration-resistant prostate cancer, which often perceived as a milestone achievement in cancer immunotherapy, subsequent progress in prostate cancer immunotherapy development has been limite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cda644296421b184bf4827d9fd2bcdf
https://doi.org/10.1158/1538-7445.am2019-4621

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