Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jessie, McKenna"'
Autor:
Natalie E Farrawell, Monique Bax, Luke McAlary, Jessie McKenna, Simon Maksour, Dzung Do-Ha, Stephanie L Rayner, Ian P Blair, Roger S Chung, Justin J Yerbury, Lezanne Ooi, Darren N Saunders
Publikováno v:
Human Molecular Genetics.
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative disorders that share pathological features, including the aberrant accumulation of ubiquitinated protein inclusions within motor neurons. Previously, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250022409eefdc6a3a11d8a4478977ba
https://doi.org/10.1093/hmg/ddad063
https://doi.org/10.1093/hmg/ddad063
Autor:
Monique Bax, Jessie McKenna, Dzung Do-Ha, Claire H. Stevens, Sarah Higginbottom, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Natalie E. Farrawell, Martin Engel, Philip Poronnik, Justin J. Yerbury, Darren N. Saunders, Lezanne Ooi
Publikováno v:
Cells, Vol 8, Iss 6, p 581 (2019)
The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs d
Externí odkaz:
https://doaj.org/article/fb3bfa9cf941450b97ac10ec0bf3e5ef
Autor:
Ashwinie A. Ukuwela, Carlos Opazo, Darren N. Saunders, Zhiguang Xiao, B. Zhang, C.H. Mawal, Paul R. Gooley, Jessie McKenna, Mark Greenough, H. Trytell, Richard Burke, A. Ramírez, C.M. Lim, A. Lotan, Ashley I. Bush
SUMMARYNutrient copper supply is critical for cell growth and differentiation, and its disturbance is associated with major pathologies including cancer and neurodegeneration. Although increasing copper bioavailability in late Precambrian facilitated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fdc93fc9c52606c6e1410cb089abefd
https://doi.org/10.1101/2021.02.15.431211
https://doi.org/10.1101/2021.02.15.431211
Autor:
Andrew Burgess, Darren N. Saunders, Sebastian Patzke, Kari Anne Myrum Frikstad, Robert F. Shearer, Rachael A. McCloy, Jessie McKenna, Niantao Deng, Trond Stokke
Publikováno v:
Molecular Biology of the Cell. 29:1542-1554
Primary cilia are crucial for signal transduction in a variety of pathways, including hedgehog and Wnt. Disruption of primary cilia formation (ciliogenesis) is linked to numerous developmental disorders (known as ciliopathies) and diseases, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d07c4f7df41aaf543dae166691c72350
https://doi.org/10.1091/mbc.e17-04-0248
https://doi.org/10.1091/mbc.e17-04-0248
Autor:
Kara L. Vine, Jessie McKenna, Prajwal Ciryam, Isabella A. Lambert-Smith, Kristen Mitchell, Natalie E. Farrawell, Darren N. Saunders, Justin J. Yerbury, Luke McAlary
Publikováno v:
Journal of Cell Science.
A hallmark of amyotrophic lateral sclerosis (ALS) pathology is the accumulation of ubiquitylated protein inclusions within motor neurons. Recent studies suggest the sequestration of ubiquitin (Ub) into inclusions reduces the availability of free Ub,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d5c9803c0470e8a49e1f3d232e6db4
https://doi.org/10.1242/jcs.209122
https://doi.org/10.1242/jcs.209122
Autor:
Natalie E, Farrawell, Isabella, Lambert-Smith, Kristen, Mitchell, Jessie, McKenna, Luke, McAlary, Prajwal, Ciryam, Kara L, Vine, Darren N, Saunders, Justin J, Yerbury
Publikováno v:
Journal of cell science. 131(11)
A hallmark of amyotrophic lateral sclerosis (ALS) pathology is the accumulation of ubiquitylated protein inclusions within motor neurons. Recent studies suggest the sequestration of ubiquitin (Ub) into inclusions reduces the availability of free Ub,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1efb999a589fc65a0f3c58c6e14ab618
https://pubmed.ncbi.nlm.nih.gov/29748379
https://pubmed.ncbi.nlm.nih.gov/29748379
Autor:
Natalie E. Farrawell, Isabella A. Lambert-Smith, Kristen Mitchell, Prajwal Ciryam, Jessie McKenna, Kara L. Vine, Justin J. Yerbury, Darren N. Saunders, Luke McAlary
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving the selective death of upper and lower motor neurons in the primary motor cortex and spinal cord. A hallmark of ALS pathology is the accumulation of ubiquitinated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5223c3a45375e56ba3d8fd08c24a4fc9
Autor:
Andrew J. Hoy, Robert F. Shearer, Mary Iconomou, David Miller, Andrew V. Biankin, Marina Pajic, Leonid A. Sazanov, John V. Pearson, Mark J. Cowley, Mark Pinese, Darren N. Saunders, Nicola Waddell, Jessie McKenna, Seher Balaban, Nigel Turner, Rae-Anne Hardie, Ellen van Dam, Silas G. Villas-Boas, Ting-Li Han, Sean M. Grimmond
Publikováno v:
Cancer & Metabolism
Background Pancreatic cancer has a five-year survival rate of ~8%, with characteristic molecular heterogeneity and restricted treatment options. Targeting metabolism has emerged as a potentially effective therapeutic strategy for cancers such as panc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea2a302f9044663ba29e04e9c92369
https://eprints.gla.ac.uk/137229/1/137229.pdf
https://eprints.gla.ac.uk/137229/1/137229.pdf
Autor:
Darren N. Saunders, Sebastian Patzke, Trond Stokke, Kari-Anne Myrum Frikstad, Rachael A. McCloy, Jessie McKenna, Andrew Burgess, Niantao Deng, Robert F. Shearer
Primary cilia are crucial for signal transduction in a variety of pathways, including Hedgehog and Wnt. Disruption of primary cilia formation (ciliogenesis) is linked to numerous developmental disorders (known as ciliopathies) and diseases, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97725ec2c3f63ea7ee4ee27bc0621047
Autor:
Lezanne Ooi, Natalie E. Farrawell, Philip Poronnik, Darren N. Saunders, Claire H. Stevens, Martin Engel, Jessie McKenna, Justin J. Yerbury, Monique Bax, Dzung Do-Ha, Mauricio Castro Cabral-da-Silva, Sarah L. Higginbottom, Rachelle Balez
Publikováno v:
Cells
Volume 8
Issue 6
Cells, Vol 8, Iss 6, p 581 (2019)
Volume 8
Issue 6
Cells, Vol 8, Iss 6, p 581 (2019)
The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b54925a0ea426d45761ad60a88efcb5
https://doi.org/10.3390/cells8060581
https://doi.org/10.3390/cells8060581