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of 4
pro vyhledávání: '"Jessica Zaid"'
Autor:
Danny Luan, Benyamin Dadpey, Jessica Zaid, Pania E. Bridge-Comer, Julia H. DeLuca, Wenmin Xia, Joshua Castle, Shannon M. Reilly
Complex bidirectional crosstalk between adipocytes and adipose tissue immune cells plays an important role in regulating adipose function, inflammation, and insulin responsiveness. Adipocytes secrete the pleiotropic cytokine IL-6 in response to both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539a1f526cdf1810c397f1bf5d7d240c
https://doi.org/10.1101/2022.07.19.500620
https://doi.org/10.1101/2022.07.19.500620
Autor:
Deepak Yadav, Tani-Ann Lee, Brian Grot, Jay Singh, Emma Langley, Chen Li, Johnovan Kim, Jessica Zaid
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A742-A742
BackgroundAn emerging class of new protease-activatable prodrugs designed to enhance on-target activity and reduce off-target toxicity are being actively developed. Cytokines are complex immune mediators which display potent anti-tumor activity in pr
Autor:
Deepak Yadav, Brian Grot, Johnavon Kim, Emma Langley, Phillip Kim, Jessica Zaid, Chen Li, Tani-Ann Lee
Publikováno v:
Cancer Research. 81:1745-1745
Recombinant IL-2 (aldesleukin) is a potent T cell proliferation and differentiation factor and is an approved immunotherapy for advanced melanoma and renal cell carcinoma. Despite the remarkable and durable remissions induced by IL-2 in a subset of t
Autor:
Jessica Zaid, Christopher Liddle, Alan R. Saltiel, Xiaoling Peng, Omer Keinan, Maryam Ahmadian, BreAnne Poirier, Julia H DeLuca, Peng Zhao, Chao-Wei Hung, Benyamin Dadpey, Donald Lu, Michael Downes, Shannon M. Reilly, Ruth T. Yu, Andrew V. Gomez, Ronald M. Evans, Anne N. Murphy
Publikováno v:
Nature metabolism
Catecholamines stimulate the mobilization of stored triglycerides in adipocytes to provide fatty acids (FAs) for other tissues. However, a large proportion is taken back up and either oxidized or re-esterified. What controls the disposition of these