Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jessica Wingerath"'
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
In this figure, the liver damage induced by heterologous, DC-based immune responses is illustrated. Mice were primed with dendritic cells and subjected to different booster immunizations consisting of variable combinations of anti-CD40, Poly I:C and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf4be9562153a9d8856f1784aaf9336
https://doi.org/10.1158/0008-5472.22415697.v1
https://doi.org/10.1158/0008-5472.22415697.v1
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
This table contains the sequences of the used neoantigen peptides, their affinity according to MHC-NET and the magnitude of the induced CD8 T cell immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f5b2f2ae7051a3d18044f82444132a
https://doi.org/10.1158/0008-5472.22415694.v1
https://doi.org/10.1158/0008-5472.22415694.v1
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
This figure demonstrates the spectrum of secreted cytokines in CD8 T cells induced by DC/CoAT vaccinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318256a412ae2124fa949709fc6b2468
https://doi.org/10.1158/0008-5472.22415703
https://doi.org/10.1158/0008-5472.22415703
Data from CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
Antagonistic antibodies targeting coinhibitory receptors have revolutionized the treatment of cancer by inducing durable immune responses and clinical remissions in patients. In contrast, success of agonistic costimulatory antibodies has thus far bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c2408e1090b6b0871e61891baef6dc
https://doi.org/10.1158/0008-5472.c.6509358.v1
https://doi.org/10.1158/0008-5472.c.6509358.v1
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
This figure demonstrates the magnitude of DC/CoAT vaccinations induced with different agonistic antibodies (anti-CD40, anti-CD137 and anti-OX40)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c6f19783ffe1459b4a1e3926ba7474
https://doi.org/10.1158/0008-5472.22415700
https://doi.org/10.1158/0008-5472.22415700
Autor:
Thomas C. Wirth, Florian Kühnel, Michael P. Manns, Christine S. Falk, Engin Gürlevik, Norman Woller, Sarah Knocke, Jessica Wingerath, Dmitrij Ostroumov, Supot Nimanong
This figure demonstrates the ability of CD8 T cells induced by DC/CoAT immunizations to migrate to the bronchoalveolar space
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3249bfe8a0328b09cbdf35f057a44e7
https://doi.org/10.1158/0008-5472.22415706.v1
https://doi.org/10.1158/0008-5472.22415706.v1
Autor:
Stephanie Roessler, Florian Kühnel, Tobias Eggert, Michael P. Manns, Oliver Dittrich-Breiholz, Norman Woller, Moritz Kleine, Thomas Wirth, Sven Nahnsen, Kai Timrott, Dmitrij Ostroumov, Stefan Czemmel, Jessica Wingerath, Steven Duong, Wolf Ramackers
Publikováno v:
Hepatology (Baltimore, Md.)References. 73(4)
BACKGROUND AND AIMS Programmed death 1 (PD-1) checkpoint inhibition has shown promising results in patients with hepatocellular carcinoma, inducing objective responses in approximately 20% of treated patients. The roles of other coinhibitory molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e673e8c42aedab9f7648f8853ca270f
https://pubmed.ncbi.nlm.nih.gov/35561049
https://pubmed.ncbi.nlm.nih.gov/35561049
Autor:
Tobias Eggert, Wolf Ramackers, Dmitrij Ostroumov, Stefan Czemmel, Florian Kühnel, Thomas Wirth, Norman Woller, Moritz Kleine, Stephanie Roessler, Sven Nahnsen, Michael P. Manns, Kai Timrott, Jessica Wingerath, Oliver Dittrich-Breiholz, S Duong
Publikováno v:
Zeitschrift für Gastroenterologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588ec0100dc4c77715eb4e470870d623
https://doi.org/10.1055/s-0039-3402198
https://doi.org/10.1055/s-0039-3402198
Autor:
Daniel D. Pinschewer, Jessica Wingerath, Klaus Orlinger, Dmitrij Ostroumov, Michael P. Manns, Thomas Wirth, Norman Woller, Ursula Berka, Florian Kühnel
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 25(11)
Successful vaccination against cancer and infectious diseases relies on the induction of adaptive immune responses that induce high-titer antibodies or potent cytoxic T cell responses. In contrast to humoral vaccines, the amplification of cellular im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d1e5171358c7d87bf3e51e081ed4c3
https://pubmed.ncbi.nlm.nih.gov/28803862
https://pubmed.ncbi.nlm.nih.gov/28803862
Autor:
Mobarak Abu Mraheil, Heiko Wendt, Trinad Chakraborty, Uwe Linne, Renate Frantz, Thomas Wirth, Jessica Wingerath, Lisa Teubner
Publikováno v:
International journal of medical microbiology : IJMM. 307(3)
Bacterial trans-translation is the main quality control mechanism employed to relieve stalled ribosomes. Trans-translation is mediated by the small protein B (SmpB) and transfer-mRNA (tmRNA) ribonucleoprotein complex, which interacts with translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb107ef87a68794c6e1f8f9ea00c7720
https://pubmed.ncbi.nlm.nih.gov/28202229
https://pubmed.ncbi.nlm.nih.gov/28202229