Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jessica Valli"'
Autor:
Frederic Li Mow Chee, Bruno Beernaert, Billie G. C. Griffith, Alexander E. P. Loftus, Yatendra Kumar, Jimi C. Wills, Martin Lee, Jessica Valli, Ann P. Wheeler, J. Douglas Armstrong, Maddy Parsons, Irene M. Leigh, Charlotte M. Proby, Alex von Kriegsheim, Wendy A. Bickmore, Margaret C. Frame, Adam Byron
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Cells transmit mechanical force to the nucleus via the cytoskeleton. Here, the authors reveal a role for the actin regulator Mena in force transmission at the nuclear envelope, where it regulates nuclear architecture, chromatin organization and gene
Externí odkaz:
https://doaj.org/article/c362f4cc95db4024a0d3eb4b310fffac
Autor:
Hanna K. Buist, Urszula Luchowska-Stańska, Boy van Basten, Jessica Valli, Brian O. Smith, George S. Baillie, Colin Rickman, Bryon Ricketts, Alex Davidson, Ryan Hannam, Joanne Sunderland, Stephen J. Yarwood
Publikováno v:
Cells, Vol 10, Iss 9, p 2307 (2021)
An exchange protein directly activated by cAMP 1 (EPAC1) is an intracellular sensor for cAMP that is involved in a wide variety of cellular and physiological processes in health and disease. However, reagents are lacking to study its association with
Externí odkaz:
https://doaj.org/article/a89d1e2a0a6848fdafc5f56006531a1d
Autor:
Tom Beneke, François Demay, Edward Hookway, Nicole Ashman, Heather Jeffery, James Smith, Jessica Valli, Tomas Becvar, Jitka Myskova, Tereza Lestinova, Shahaan Shafiq, Jovana Sadlova, Petr Volf, Richard John Wheeler, Eva Gluenz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007828 (2019)
The protozoan parasite Leishmania possesses a single flagellum, which is remodelled during the parasite's life cycle from a long motile flagellum in promastigote forms in the sand fly to a short immotile flagellum in amastigotes residing in mammalian
Externí odkaz:
https://doaj.org/article/9ca55d87fc984bd0871bdf13faa8f1ce
Publikováno v:
Royal Society Open Science, Vol 4, Iss 5 (2017)
Clustered regularly interspaced short palindromic repeats (CRISPR), CRISPR-associated gene 9 (Cas9) genome editing is set to revolutionize genetic manipulation of pathogens, including kinetoplastids. CRISPR technology provides the opportunity to deve
Externí odkaz:
https://doaj.org/article/38beb60601a64a55a082d30635ce164c
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134432 (2015)
In a variety of eukaryotes, flagella play important roles both in motility and as sensory organelles that monitor the extracellular environment. In the parasitic protozoan Leishmania mexicana, one glucose transporter isoform, LmxGT1, is targeted sele
Externí odkaz:
https://doaj.org/article/00ce9c711a5742d59c834fb11786f39f
Autor:
Peter Connolly, Yash Shah, Jessica Valli, Arran J. Sykes, James Grant, Claudio Accarino, Yoann Altmann, Colin Rickman, David R. Cumming, Gerald Buller
Publikováno v:
Emerging Imaging and Sensing Technologies for Security and Defence VII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb132f081cbd5168bee5ca7a75a12eb
https://doi.org/10.1117/12.2643396
https://doi.org/10.1117/12.2643396
Autor:
Matthew J. Broadhead, Calum Bonthron, Julia Waddington, William V. Smith, Maite F. Lopez, Sarah Burley, Jessica Valli, Fei Zhu, Noboru H. Komiyama, Colin Smith, Seth G. N. Grant, Gareth B. Miles
Publikováno v:
Broadhead, M J, Bonthron, C, Waddington, J, Smith, W V, Lopez, M F, Burley, S, Valli, J, Zhu, F, Komiyama, N H, Smith, C, Grant, S G N & Miles, G B 2022, ' Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis ', Acta Neuropathologica . https://doi.org/10.1007/s00401-022-02412-9
Authors would like to acknowledge the following funders: Motor Neurone Disease (MND) Association UK (Miles/Apr18/863-791), the Euan MacDonald Centre and Chief Scientist Office, The European Research Council (ERC) under the European Union’s Horizon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4703da7499094d5780f0b2204dfce7e
https://hdl.handle.net/10023/25081
https://hdl.handle.net/10023/25081
Autor:
Noboru H. Komiyama, Matthew J. Broadhead, Fei Zhu, WV Smith, Sgn Grant, Gareth B. Miles, Calum Bonthron, MF Lopez, Colin Smith, S Burley, Jessica Valli, J Waddington
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS. Given that astrocytes make specialised contacts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53682ca31c106bc67a91f985a828d448
https://doi.org/10.1101/2021.10.28.465435
https://doi.org/10.1101/2021.10.28.465435
Autor:
Peter W. R. Connolly, Jessica Valli, Yash D. Shah, Yoann Altmann, James Grant, Claudio Accarino, Colin Rickman, David R. S. Cumming, Gerald S. Buller
Publikováno v:
Journal of Biophotonics. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430555bae968aaf953f466f409285987
https://doi.org/10.1002/jbio.202170022
https://doi.org/10.1002/jbio.202170022
Publikováno v:
Kölln, L S, Salem, O, Valli, J, Hansen, C G & Mcconnell, G 2022, ' Label2label: Training a neural network to selectively restore cellular structures in fluorescence microscopy ', Journal of Cell Science, vol. 135, no. 3, jcs258994 . https://doi.org/10.1242/jcs.258994
Immunofluorescence microscopy is routinely used to visualise the spatial distribution of proteins that dictates their cellular function. However, unspecific antibody binding often results in high cytosolic background signals, decreasing the image con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed1cc1281e28964e8649323adc47667
https://pubmed.ncbi.nlm.nih.gov/35022745
https://pubmed.ncbi.nlm.nih.gov/35022745