Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jessica Thomes-Pepin"'
Autor:
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Kelly J. Wilkinson, Emily M. Whitman-Purves, Jayanthi Lea, John M. Schallenkamp, Nabil Adra, Leonard J. Appleman, Mitchell Alden, Jessica Thomes Pepin, John A. Ellerton, Andrew Poklepovic, Adam Walter, Murtuza M. Rampurwala, William R. Robinson, Liam Il-Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock
Publikováno v:
Cancer Research. 83:CT161-CT161
Background: Dual checkpoint inhibition with Anti-PD-1 and anti-CTLA4 checkpoint inhibitors have proven to be effective in several malignancies but their potential role in numerous rare solid cancers is yet to be established. This study presents the f
Autor:
Luciana Molinero, Christopher J. Darus, Xiaohua Wu, Johanna Mäenpää, Charles K. Anderson, Nicoletta Colombo, Aikou Okamoto, Giovanni Scambia, Y. García, Fan Wu, Michael A. Bookman, Yvonne G. Lin, Victor Khor, L. Willmott, Jalid Sehouli, Tashanna Myers, Michalis Liontos, Rustem Safin, Michael A. Gold, Cagatay Taskiran, Katina Robison, Austin Miller, Vidya Maiya, Sudarshan K. Sharma, Carol Aghajanian, Sandro Pignata, Jessica Thomes-Pepin, Kathleen N. Moore
Publikováno v:
J Clin Oncol
Journal of Clinical Oncology
Journal of Clinical Oncology
Purpose: to evaluate the addition of the humanized monoclonal antiprogrammed death ligand-1 (PD-L1) antibody, atezolizumab, to platinum-based chemotherapy and bevacizumab in newly diagnosed stage III or IV ovarian cancer (OC). Methods: this multicent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea89f9ab83f69d1132450dbd7ec3832
http://hdl.handle.net/10281/327598
http://hdl.handle.net/10281/327598
Autor:
Debabrata Chakravarti, Horacio Cardenas, Jessica Thomes Pepin, Guanglong Jiang, Harikrishna Nakshatri, J. Brandon Parker, Daniela Matei, Yunlong Liu, Salvatore Condello, Kenneth P. Nephew
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 3, Iss 1, Pp 1-14 (2019)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-14 (2019)
Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To identify gene signatures regulated by epigenetic mechanisms in OC cells carrying BRCA1 mutations, we ass
Autor:
Jessica Thomes-Pepin, Chris Stephenson
Publikováno v:
An Atlas of Gynecologic Oncology ISBN: 9781351141680
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74acb8ca113208ff9747589fc45fd87
https://doi.org/10.1201/9781351141680-2
https://doi.org/10.1201/9781351141680-2
Ovarian cancer (OC) is characterized by complex epigenetic alterations, including aberrant DNA methylation, histone modifications, and nucleosome positioning. Advances in the sequencing technologies over the past decade have enabled deeper characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b280610789a13ff7122087d7967f03
https://doi.org/10.1016/b978-0-12-803741-6.00003-3
https://doi.org/10.1016/b978-0-12-803741-6.00003-3
Autor:
Daphne W. Bell, Jennifer Bergstrom, Michael J. Birrer, David M. Boruta, Horacio Cardenas, Lorenzo Ceppi, Dennis S. Chi, Bradley L. Collins, Don S. Dizon, Louis Dubeau, Amanda N. Fader, Amalia N. Gonzalez, Ashley Hanbury, Fady Khoury-Collado, Panagiotis A. Konstantinopoulos, Joyce F. Liu, Lainie P. Martin, Daniela Matei, Kenneth P. Nephew, M.H.M. Oonk, Richard T. Penson, Jessica Thomes Pepin, Andrea L. Russo, Mary E. Sabatini, Russell J. Schilder, Angeles Alvarez Secord, Ie-Ming Shih, Sharareh Siamakpour-Reihani, Caryn M. St. Clair, Jose Teixeira, Krishnansu S. Tewari, Mary Ellen Urick, A.G.J. van der Zee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::641b66faeb1eab1d90f2785d8e14f295
https://doi.org/10.1016/b978-0-12-803741-6.00025-2
https://doi.org/10.1016/b978-0-12-803741-6.00025-2
Autor:
Guanglong Jiang, Jessica Thomes Pepin, Yunlong Liu, Salvatore Condello, Daniela Matei, K. P. Nephew, Horacio Cardenas
Publikováno v:
Cancer Research. 78:4319-4319
Inactivating mutations of the breast cancer type 1 susceptibility protein (BRCA1) have been implicated in breast and ovarian cancer (OC) initiation. Having observed differential response of OC cells to histone deacetylase inhibitors (HDACi) dependent
Autor:
Thomas D. Hurley, Junjie Li, Jessica Thomes-Pepin, Ji-Xin Cheng, Daniela Matei, Salvatore Condello, Xiaoxiao Ma, Yu Xia
Publikováno v:
Clinical Cancer Research. 23:AP21-AP21
OBJECTIVES: Lack of sensitive single-cell analysis tools has limited the characterization of the metabolic activity of cancer stem cells (CSCs). The objectives of this study were to identify and target metabolic pathways specifically deregulated in o
Autor:
Ji-Xin Cheng, Junjie Li, Thomas D. Hurley, Daniela Matei, Yu Xia, Jessica Thomes-Pepin, Salvatore Condello, Xiaoxiao Ma
Publikováno v:
Cell Stem Cell. 20:303-314.e5
Lack of sensitive single-cell analysis tools has limited the characterization of metabolic activity in cancer stem cells. By hyperspectral-stimulated Raman scattering imaging of single living cells and mass spectrometry analysis of extracted lipids,