Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jessica T. Chang"'
Autor:
Caroline Kumsta, Jessica T. Chang, Reina Lee, Ee Phie Tan, Yongzhi Yang, Rute Loureiro, Elizabeth H. Choy, Shaun H. Y. Lim, Isabel Saez, Alexander Springhorn, Thorsten Hoppe, David Vilchez, Malene Hansen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
While the cellular recycling process autophagy has been linked to aging, the impact of selective autophagy on lifespan remains unclear. Here Kumsta et al. show that the autophagy receptor p62/SQSTM1 is required for hormetic benefits and p62/SQSTM1 ov
Externí odkaz:
https://doaj.org/article/1e02eb157af547f08c179b3732ae4d95
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Mild heat stress has beneficial effects on organismal health and survival. Here, Kumstaet al. show that a mild heat shock and HSF-1 overexpression induce autophagy in multiple tissues of C. elegansand autophagy-related genes are essential for both he
Externí odkaz:
https://doaj.org/article/88a82688b15d44639dd224cca7456959
Autor:
Philip R. McQuary, Chen-Yu Liao, Jessica T. Chang, Caroline Kumsta, Xingyu She, Andrew Davis, Chu-Chiao Chu, Sara Gelino, Rafael L. Gomez-Amaro, Michael Petrascheck, Laurence M. Brill, Warren C. Ladiges, Brian K. Kennedy, Malene Hansen
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2059-2067 (2016)
Deficiency of S6 kinase (S6K) extends the lifespan of multiple species, but the underlying mechanisms are unclear. To discover potential effectors of S6K-mediated longevity, we performed a proteomics analysis of long-lived rsks-1/S6K C. elegans mutan
Externí odkaz:
https://doaj.org/article/29b2484ea09e4ed5ac62471d7032b3bc
Publikováno v:
eLife, Vol 6 (2017)
Autophagy has been linked to longevity in many species, but the underlying mechanisms are unclear. Using a GFP-tagged and a new tandem-tagged Atg8/LGG-1 reporter, we quantified autophagic vesicles and performed autophagic flux assays in multiple tiss
Externí odkaz:
https://doaj.org/article/0e1415baebd54b8d9a580477b510574c
Autor:
Sara Gelino, Jessica T Chang, Caroline Kumsta, Xingyu She, Andrew Davis, Christian Nguyen, Siler Panowski, Malene Hansen
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006271 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1006135.].
Externí odkaz:
https://doaj.org/article/ee31d33163ed4ad7b05442c90c27e654
Publikováno v:
Aging ISBN: 9781071605912
Methods Mol Biol
Methods Mol Biol
The cellular recycling process of autophagy is essential for survival, development, and homeostasis. Autophagy also plays an important role in aging and has been linked to longevity in many species, including the nematode C. elegans. Study of the phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6aa89acccf510aa1e9d872def56900
https://doi.org/10.1007/978-1-0716-0592-9_24
https://doi.org/10.1007/978-1-0716-0592-9_24
Publikováno v:
Aging ISBN: 9781071605912
The cellular recycling process of autophagy is essential for survival, development, and homeostasis. Autophagy also plays an important role in aging and has been linked to longevity in many species, including the nematode C. elegans. Study of the phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88869c713849124db9d7fc5570dc746
https://doi.org/10.1007/978-1-0716-0592-9_17
https://doi.org/10.1007/978-1-0716-0592-9_17
Autor:
Alexander Springhorn, Jessica T. Chang, David Vilchez, Reina Lee, Isabel Saez, Thorsten Hoppe, Malene Hansen, Rute Loureiro, Caroline Kumsta, Shaun H. Y. Lim, Elizabeth H. Choy, Ee Phie Tan, Yongzhi Yang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Autophagy can degrade cargos with the help of selective autophagy receptors such as p62/SQSTM1, which facilitates the degradation of ubiquitinated cargo. While the process of autophagy has been linked to aging, the impact of selective autophagy in li
Autor:
Jamie W. Burnside, Bryan S. Robinson, Curt Schieler, Jessica T. Chang, Kenneth Aquino, Kathleen Riesing
Publikováno v:
Free-Space Laser Communications XXXI.
Free-space optical communications in space offer many benefits over established radio frequency based communication links; in particular, high beam directivity results in efficient power usage. Such a reduced power requirement is particularly appeali
Autor:
Malene Hansen, Jessica T. Chang
Publikováno v:
eLife
Autophagy has been linked to longevity in many species, but the underlying mechanisms are unclear. Using a GFP-tagged and a new tandem-tagged Atg8/LGG-1 reporter, we quantified autophagic vesicles and performed autophagic flux assays in multiple tiss