Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jessica Sudderth"'
Autor:
Kenneth E. Huffman, Long Shan Li, Ryan Carstens, Hyunsil Park, Luc Girard, Kimberley Avila, Shuguang Wei, Rahul Kollipara, Brenda Timmons, Jessica Sudderth, Nawal Bendris, Jiyeon Kim, Pamela Villalobos, Junya Fujimoto, Sandra Schmid, Ralph J. Deberardinis, Ignacio Wistuba, John Heymach, Ralf Kittler, Esra A. Akbay, Bruce Posner, Yuzhuo Wang, Stephen Lam, Steven A. Kliewer, David J. Mangelsdorf, John D. Minna
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The glucocorticoid receptor (GR) is an important anti-cancer target in lymphoid cancers but has been understudied in solid tumors like lung cancer, although glucocorticoids are often given with chemotherapy regimens to mitigate side effects. Here, we
Externí odkaz:
https://doaj.org/article/12a85fec027a43f998070bed490eb234
Autor:
Sarah MacPherson, Sarah Keyes, Marisa K. Kilgour, Julian Smazynski, Vanessa Chan, Jessica Sudderth, Tim Turcotte, Adria Devlieger, Jessie Yu, Kimberly S. Huggler, Jason R. Cantor, Ralph J. DeBerardinis, Christopher Siatskas, Julian J. Lum
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 380-393 (2022)
Ex vivo expansion conditions used to generate T cells for immunotherapy are thought to adopt metabolic phenotypes that impede therapeutic efficacy in vivo. The comparison of five different culture media used for clinical T cell expansion revealed uni
Externí odkaz:
https://doaj.org/article/f33f2e28b0854ba7b43b89b360c06564
Autor:
Pravat Kumar Parida, Mauricio Marquez-Palencia, Akash K. Kaushik, Kangsan Kim, Vidhya Nair, Jessica Sudderth, Hieu Vu, Lauren Zacharias, Ralph DeBerardinis, Srinivas Malladi
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101345- (2022)
Summary: Analyzing the metabolic dependencies of tumor cells is vital for cancer diagnosis and treatment. Here, we describe a protocol for 13C-stable glucose and glutamine isotope tracing in mice HER2+ breast cancer brain metastatic lesions. We descr
Externí odkaz:
https://doaj.org/article/e0b5c74ee75b49fa8e475f282fe365d9
Autor:
Stefan Stender, Vlad G. Zaha, Craig R. Malloy, Jessica Sudderth, Ralph J. DeBerardinis, Jae Mo Park
Publikováno v:
Hepatology Communications, Vol 4, Iss 3, Pp 425-433 (2020)
Carbon‐13 magnetic resonance spectroscopy (MRS) following oral intake of 13C‐labeled glucose is the gold standard for imaging glycogen metabolism in humans. However, the temporal resolution of previous studies has been >13 minutes. Here, we descr
Externí odkaz:
https://doaj.org/article/e975fa7feda54cc8ba025fb0cc728917
Autor:
Ebony M. Flowers, Jessica Sudderth, Lauren Zacharias, Glenda Mernaugh, Roy Zent, Ralph J. DeBerardinis, Thomas J. Carroll
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Polycystic kidney disease (PKD) is characterized by the formation of large fluid-filled cysts. Here Flowers and colleagues show that loss of Lkb1, downregulated in PKD, renders kidney cells dependent on glutamine for growth, and suggest that inhibiti
Externí odkaz:
https://doaj.org/article/2bb7dc69954d4d07aea6f8ecaf917710
Autor:
Barrett L. Updegraff, Xiaorong Zhou, Yabin Guo, Mahesh S. Padanad, Pei-Hsuan Chen, Chendong Yang, Jessica Sudderth, Carla Rodriguez-Tirado, Luc Girard, John D. Minna, Prashant Mishra, Ralph J. DeBerardinis, Kathryn A. O’Donnell
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2223-2233.e6 (2018)
Summary: Pathways underlying metabolic reprogramming in cancer remain incompletely understood. We identify the transmembrane serine protease TMPRSS11B as a gene that promotes transformation of immortalized human bronchial epithelial cells (HBECs). TM
Externí odkaz:
https://doaj.org/article/8830c3d646e74fa1ad38b656919ff687
Autor:
Nathan J. Lanning, Brendan D. Looyenga, Audra L. Kauffman, Natalie M. Niemi, Jessica Sudderth, Ralph J. DeBerardinis, Jeffrey P. MacKeigan
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 907-917 (2014)
Altered cellular bioenergetics and mitochondrial function are major features of several diseases, including cancer, diabetes, and neurodegenerative disorders. Given this important link to human health, we sought to define proteins within mitochondria
Externí odkaz:
https://doaj.org/article/da142fcd883240b8a28c4b9f3921e3b7
Autor:
Michael A. White, Ralf Kittler, Georgina V. Long, Helen Rizos, Lynda Chin, Noelle S. Williams, Jef K. De Brabander, Yonghao Yu, Jennifer A. Wargo, Michael A. Davies, Claudia Wellbrock, Ralph J. Deberardinis, Kakajan Komurov, Jessica Sudderth, Michael P. Smith, Ugur Eskiocak, Tracy I. Rosales, Aubhishek Zaman, Ming Ding, Jose Garcia-Rodriguez, Changguang Wang, Caroline G. Humphries, Hailei Zhang, Rahul K. Kollipara, Saurabh Mendiratta, Elizabeth A. McMillan, Banu Eskiocak
Extended Experimental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1039b26720af4f97108c00b1b555a8ab
https://doi.org/10.1158/2159-8290.22531921.v1
https://doi.org/10.1158/2159-8290.22531921.v1
Autor:
Michael A. White, Ralf Kittler, Georgina V. Long, Helen Rizos, Lynda Chin, Noelle S. Williams, Jef K. De Brabander, Yonghao Yu, Jennifer A. Wargo, Michael A. Davies, Claudia Wellbrock, Ralph J. Deberardinis, Kakajan Komurov, Jessica Sudderth, Michael P. Smith, Ugur Eskiocak, Tracy I. Rosales, Aubhishek Zaman, Ming Ding, Jose Garcia-Rodriguez, Changguang Wang, Caroline G. Humphries, Hailei Zhang, Rahul K. Kollipara, Saurabh Mendiratta, Elizabeth A. McMillan, Banu Eskiocak
Supplemental Figure S1. Integrative Analysis of Functional Genomics and Copy Number Variation in Melanoma Cells and Tissues, Supplemental Figure S2. Elastic Net Derived Biomarker Results for Melanoma Survival Genes and Detection of These Biomarkers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2582c174f25f18c51c5ccc75c043f0
https://doi.org/10.1158/2159-8290.22531915
https://doi.org/10.1158/2159-8290.22531915
Autor:
Ralph J. DeBerardinis, Jeffrey G. McDonald, Robert G. Bachoo, Tuyen Dang, Jessica Sudderth, Chendong Yang
Supplementary Methods, Figures 1-5, Table 1 from Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d2ccb02d6af762cbb053967653ae43
https://doi.org/10.1158/0008-5472.22382300
https://doi.org/10.1158/0008-5472.22382300