Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jessica Sheu"'
Autor:
Nicole T Schirle, Jessica Sheu-Gruttadauria, Stanley D Chandradoss, Chirlmin Joo, Ian J MacRae
Publikováno v:
eLife, Vol 4 (2015)
MicroRNAs (miRNAs) direct post-transcriptional regulation of human genes by guiding Argonaute proteins to complementary sites in messenger RNAs (mRNAs) targeted for repression. An enigmatic feature of many conserved mammalian miRNA target sites is th
Externí odkaz:
https://doaj.org/article/b488e6ba7de44b14ac4ed2010e91cec2
Publikováno v:
Biophysical Journal. 121:293a-294a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7a97701c8d959a9ee355eea4dda6655
https://doi.org/10.1016/j.bpj.2021.11.1286
https://doi.org/10.1016/j.bpj.2021.11.1286
Publikováno v:
Cold Spring Harb Symp Quant Biol
microRNAs (miRNAs) are crucial for post-transcriptional regulation of messenger RNAs. “Classical” miRNA targets predominantly interact with the miRNA seed sequence located in the miRNA 5′ region. Interestingly, certain transcripts that exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7221d2faf629d9c87c99aef7a7af13c
https://pubmed.ncbi.nlm.nih.gov/32019864
https://pubmed.ncbi.nlm.nih.gov/32019864
Publikováno v:
Biophysical Journal. 121:497a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4279dc452600da2c75941af3d7b7f8f8
https://doi.org/10.1016/j.bpj.2021.11.300
https://doi.org/10.1016/j.bpj.2021.11.300
Autor:
Patrick J. Lau, Ashley Dvorak, Kevin Lai, Ryan Demeter, Shale Dames, Steven Henck, Katia Star, Katelyn Larkin, Bosun Min, Timothy Barnes, Manqing Hong, Jessica Sheu, Hsiao-Yun Huang, Ushati Das Chakravarty, Tzu-Chun Chen
Publikováno v:
Cancer Research. 81:327-327
RNA-seq is a powerful tool to detect tissue-specific gene expression, splicing, and genetic variations associated with disease states. However, current RNA-seq approaches have limitations due to poor signal from low-abundant transcripts. Furthermore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::925526f1a1236da912f8b11b352c5054
https://doi.org/10.1158/1538-7445.am2021-327
https://doi.org/10.1158/1538-7445.am2021-327
Autor:
Therese A. Yario, Joan A. Steitz, Jessica Sheu-Gruttadauria, Sonia Wang, Paulina Pawlica, Nicole T. Schirle Oakdale, Ian J. MacRae, Shannon Klum
Publikováno v:
Mol Cell
MicroRNAs (miRNAs) broadly regulate gene expression through association with Argonaute (Ago), which also protects miRNAs from degradation. However, miRNA stability is known to vary and is regulated by poorly understood mechanisms. A major emerging pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a312edf61eb3e42492ece0636f2e7e
https://doi.org/10.2139/ssrn.3318944
https://doi.org/10.2139/ssrn.3318944
Autor:
Jessica Sheu, Nicole Roseman, Timothy Barnes, Hsiao-Yun Huang, Ushati Das Chakravarty, Tzu-Chun Chen, Shilpa Parakh, Amy Yoder, Alisa Jackson, Anastasia Potts, Lyn Lewis, Kevin Lai
Publikováno v:
Cancer Research. 80:5863-5863
Demonstrate performance of a complete automation and reagent workflow for analysis of cfDNA from bodily fluids. The efficient extraction of cfDNA from bodily fluids is a unique challenge due to the very low concentrations of nucleic acid. The extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1eb246cd3849ef755a8419ea6630df
https://doi.org/10.1158/1538-7445.am2020-5863
https://doi.org/10.1158/1538-7445.am2020-5863
Autor:
Steve Groenewold, Patrick J. Lau, Ekaterina Star, Jessica Sheu, Tzu-Chun Chen, Kevin Lai, Steven Henck, Karissa Scott, Lynette Lewis, Ushati Das Chakravarty, Longhui Ren, Hsiao-Yun Huang, Xiaohui Wang, Manqing Hong, Bosun Min, Ramses Lopez, Tim Barnes, Jinglie Zhou
Publikováno v:
Journal of Clinical Oncology. 38:e15584-e15584
e15584 Background: Comprehensive tumor profiling using NGS is fundamentally transforming oncology research. However, converting archival tissue samples into libraries is often challenging due to the low quantity and quality of DNA. Here we present ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::292d84a8628302a9fcf6a753be94ca95
https://doi.org/10.1200/jco.2020.38.15_suppl.e15584
https://doi.org/10.1200/jco.2020.38.15_suppl.e15584
microRNAs (miRNA) guide Argonaute proteins to mRNAs targeted for repression. Target recognition occurs primarily through the miRNA seed region, composed of guide (g) nucleotides g2–g8. However, nucleotides beyond the seed are also important for som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd266cac5cf97092437db61fa98f72a4
